Zobrazeno 1 - 10 of 11 pro vyhledávání: '"A W, Boddy"'
1
The Effect of Zanoterone, a Steroidal Androgen Receptor Antagonist, in Men with Benign Prostatic Hyperplasia
Autor: Alexander W. Boddy, Bruce M. Berger, Rajfer J, John D. McConnell, Fisher Ha, David F. Mobley, Naadimuthu A, Milam D
Publikováno v: The Journal of Urology. :1060-1064
PURPOSE Zanoterone (100 to 800 mg.) versus placebo was studied in 463 patients with benign prostatic hyperplasia. MATERIALS AND METHODS Study end points were maximum urinary flow rate, American Urological Association symptom index, prostate volume, p
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::9121ba58ee477a5a9a59c875615d0d4f
https://doi.org/10.1097/00005392-199509000-00043
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2
[Untitled]
Autor: K. K. Midha, Robert O. Kringle, Fred C. Snikeris, Alexander W. Boddy, James A. Oppermann, Greg C. G. Wei
Publikováno v: Pharmaceutical Research. 12:1865-1868
Purpose. Highly variable drugs pose a problem in bioequivalence assessment because they often fail to meet current regulatory acceptance criteria for average bioequivalence (80–125%). This paper examines alternative approaches to establishing bioeq
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::643ae02f1d341459f06beaf21ea4bd69
https://doi.org/10.1023/a:1016219317744
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3
Absorption of Danazol After Administration to Different Sites of the Gastrointestinal Tract and the Relationship to Single- and Double-Peak Phenomena in the Plasma Profiles
Autor: William H. Barr, Alexander W. Boddy, William N. Charman, Bruce M. Berger, Mark Rogge
Publikováno v: The Journal of Clinical Pharmacology. 33:1207-1213
The absorption of danazol (100 mg) after oral or intraintestinal administration to the proximal jejunum or proximal ileum has been studied in healthy female subjects. The extent of danazol absorption after administration as a solubilized glycerol mon
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59ef57d52a8a63504b78dd84c2450d49
https://doi.org/10.1002/j.1552-4604.1993.tb03921.x
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4
Effect of Food and a Monoglyceride Emulsion Formulation on Danazol Bioavailability
Autor: Bruce M. Berger, Mark Rogge, Alexander W. Boddy, William N. Charman
Publikováno v: The Journal of Clinical Pharmacology. 33:381-386
The bioavailability of a single 100-mg dose of danazol delivered from the commercial formulation (hard gelatin capsule) and from an experimental lipid emulsion formulation of danazol was studied in 11 healthy female volunteers in both fed and fasted
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e895bf7f25fa806f6d0c546c01f60eca
https://doi.org/10.1002/j.1552-4604.1993.tb04673.x
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6
Preliminary study of the pharmacokinetics of oral amifloxacin in elderly subjects
Autor: J A Cook, Richard R. Brown, M H Silverman, A W Boddy, R M Stroshane, R Sauerschell
Publikováno v: Antimicrobial Agents and Chemotherapy. 34:751-754
Amifloxacin pharmacokinetics after a single oral dose in healthy elderly subjects were determined. Five males and five females aged 65 to 79 years and having creatinine clearances of 39.3 to 87.2 ml/h per kg of body weight were given a 200-mg amiflox
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71243e022ddc0eea307b6bbf8e22e88e
https://doi.org/10.1128/aac.34.5.751
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8
An approach for widening the bioequivalence acceptance limits in the case of highly variable drugs
Autor: A W, Boddy, F C, Snikeris, R O, Kringle, G C, Wei, J A, Oppermann, K K, Midha
Publikováno v: Pharmaceutical research. 12(12)
Highly variable drugs pose a problem in bioequivalence assessment because they often fail to meet current regulatory acceptance criteria for average bioequivalence (80-125%). This paper examines alternative approaches to establishing bioequivalence.S
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::13232d7dcfb75dedbc3b9ef214a02a43
https://pubmed.ncbi.nlm.nih.gov/8786957
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9
A computer simulation study of stochastic models to investigate the population dynamics of the screech owl (otus asio) under increased mortality
Autor: Philip M. North, Duncan R. Forrester, Alex W. Boddy
Publikováno v: Ecological Modelling. 40:233-263
The work reported in this paper complements an earlier study in which deterministic models were used examine the effects of additional mortality imposed on a Screech Owl, Otus asio , population. Interest lay in the compensatory mechanisms that the ow
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::c4ebccbe7b223e3a49fa1568dbb9ed85
https://doi.org/10.1016/0304-3800(88)90020-8
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