Zobrazeno 1 - 10
of 71
pro vyhledávání: '"A W, Bannon"'
Autor:
Stephen, Zicha, Randall J, Bateman, Leslie M, Shaw, Henrik, Zetterberg, Anthony W, Bannon, Wesley A, Horton, Mike, Baratta, Hartmuth C, Kolb, Iwona, Dobler, Yulia, Mordashova, Ziad S, Saad, David L, Raunig, Emmanouil Manos, Spanakis, Yan, Li, Suzanne E, Schindler, Kyle, Ferber, Carrie E, Rubel, Robert L, Martone, Christopher J, Weber, Rebecca M, Edelmayer, Emily A, Meyers, James G, Bollinger, Erin G, Rosenbaugh, William Z, Potter
Publikováno v:
Alzheimer'sdementia : the journal of the Alzheimer's AssociationREFERENCES.
This report details the approach taken to providing a dataset allowing for analyses on the performance of recently developed assays of amyloid beta (Aβ) peptides in plasma and the extent to which they improve the prediction of amyloid positivity.Alz
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::4f92a7bdcb46d9e104e3c909a55d9d98
https://pubmed.ncbi.nlm.nih.gov/35820077
https://pubmed.ncbi.nlm.nih.gov/35820077
Autor:
Rosemarie Roeloffs, Anthony W Bannon, Adam R. Brown, Alexandre J.C. Loucif, Aristos J. Alexandrou, Anthony J. Kirkup, Mathew D Fuller, Gillian Stockbridge, Edward B. Stevens, David Printzenhoff, Praveen Anand, Steve England, Claire Elizabeth Payne, Uma Anand, Peter J. Bungay, Aaron C. Gerlach, Mark L. Chapman, Kemp Mark Ian, John H. Mahoney, Rebecca L. Prime, Jonathon W Theile, Brett M Antonio, Richard P. Butt, Sharan K. Bagal
Publikováno v:
British Journal of Pharmacology. 172:2654-2670
Background and Purpose NaV1.8 ion channels have been highlighted as important molecular targets for the design of low MW blockers for the treatment of chronic pain. Here, we describe the effects of PF-01247324, a new generation, selective, orally bio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cc8c0db0b158b8bf6fded6eb148ad000
https://doi.org/10.1111/bph.13092
https://doi.org/10.1111/bph.13092
Autor:
Balu Kamaraj, Yingtao Bi, Simon Xi, Amit Das, Viswanath Devanarayan, Smriti Mishra, Matt Townsend, Philge Philip, Anthony W. Bannon, M.I. Shah, Gyan Srivastava, Sudeshna Das, Amitava Bhattacharyya, Brinda Ravikumar
Publikováno v:
Alzheimer's & Dementia. 15:P1588-P1588
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e8fd593d7702c0a7c97b35205705d6b3
https://doi.org/10.1016/j.jalz.2019.09.036
https://doi.org/10.1016/j.jalz.2019.09.036
Autor:
Douglas S. Krafte, Anthony W Bannon
Publikováno v:
Current Opinion in Pharmacology. 8:50-56
Recent scientific advances have enhanced our understanding of the role voltage-gated sodium channels play in pain sensation. Human data on Nav1.7 show that gain-of-function mutations lead to enhanced pain while loss-of-function mutations lead to Cong
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a901b2905d07331b026f88e10e94a2aa
https://doi.org/10.1016/j.coph.2007.09.007
https://doi.org/10.1016/j.coph.2007.09.007
Autor:
Tie J. Zhang, James W. Davis, Di Bian, Jean-Claude Louis, Dawn Zhu, Anthony W. Bannon, Kenneth D. Wild
Publikováno v:
Journal of Pharmacology and Experimental Therapeutics. 322:282-287
A considerable body of evidence implicates endogenous nerve growth factor (NGF) in conditions in which pain is a prominent feature, including neuropathic pain. However, previous studies of NGF antagonism in animal models of neuropathic pain have exam
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e3a431b86cb3f907016e75353b71c20
https://doi.org/10.1124/jpet.106.116236
https://doi.org/10.1124/jpet.106.116236
Autor:
Carlo van Staden, Clarence Hale, Faye Hsieh, Vu Van Ma, Anthony W. Bannon, John A. Salon, Christopher Hulme, Kirk Rorrer, Paul Tempest, Jamie Baumgartner
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 16:5066-5072
Melanin-concentrating hormone (MCH) is a cyclic 19 amino acid orexigenic neuropeptide. The action of MCH on feeding is thought to involve the activation of its respective G protein-coupled receptor MCH-R1. Consequently, antagonists that block MCH reg
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1477e27138d18f6f6598966a422cd436
https://doi.org/10.1016/j.bmcl.2006.07.040
https://doi.org/10.1016/j.bmcl.2006.07.040
Autor:
Nuria A. Tamayo, Shimin Xu, Michael G. Kelly, Duncan M. Smith, Ning Chen, Michelle Carmouche, Mark H. Norman, Martin H. Goldberg, James Davis, Christopher H. Fotsch, Clarence Hale, Ning Xi, Markian Stec, James W. Baumgartner, Premilla Arasasingham, Nianhe Han, Feng-Yin Hsieh, Qingyian Liu, Yunxin Bo, Anthony W. Bannon
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 15:1623-1627
The biological activity for a set of melanocortin-4 receptor (MC4R) agonists containing a piperazine core with an ortho-substituted aryl sulfonamide is described. Compounds from this set had binding and functional activities at MC4R less than 30 nM.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d7e26bb6cb3766754fe8c0250af2dfad
https://doi.org/10.1016/j.bmcl.2005.01.060
https://doi.org/10.1016/j.bmcl.2005.01.060
Autor:
Shu Takeda, Xiuyun Liu, Gerard Karsenty, Tony W. Bannon, Karine Clément, Jong Deok Ahn, Christian Vaisse, Hisataka Kondo, William G. Richards, Michael Starbuck, Florent Elefteriou, Xiangli Yang, Masaki Noda
Publikováno v:
Nature. 434:514-520
Bone remodelling, the mechanism by which vertebrates regulate bone mass, comprises two phases, namely resorption by osteoclasts and formation by osteoblasts; osteoblasts are multifunctional cells also controlling osteoclast differentiation. Sympathet
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d1eefcf9aab110fbd8e0267ef83521ff
https://doi.org/10.1038/nature03398
https://doi.org/10.1038/nature03398
Autor:
Narender R. Gavva, James J. S. Treanor, Todd W. Vanderah, Yusheng Qu, Jean Claude Louis, Tie J. Zhang, Frank Porreca, Kenneth D. Wild, Elizabeth M. Doherty, Rami Tamir, David C. Immke, Anthony W. Bannon, Mark H. Norman, Lana Klionsky, Judy Wang, Dawn Zhu
Publikováno v:
Journal of Pharmacology and Experimental Therapeutics. 313:474-484
The vanilloid receptor 1 (VR1 or TRPV1) is a membrane-bound, nonselective cation channel expressed by peripheral sensory neurons. TRPV1 antagonists produce antihyperalgesic effects in animal models of inflammatory and neuropathic pain. Here, we descr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::baa997157a9236df5940afebfb38eb8c
https://doi.org/10.1124/jpet.104.079855
https://doi.org/10.1124/jpet.104.079855
Autor:
James Davis, William J. Boyle, Anthony W. Bannon, Vickie E. Baracos, David L. Lacey, Xiaolan Zhou, H.Q. Han, Vered Solomon, Keith Soo-Nyung Kwak
Publikováno v:
Cancer Research. 64:8193-8198
The progressive depletion of skeletal muscle is a hallmark of many types of advanced cancer and frequently is associated with debility, morbidity, and mortality. Muscle wasting is primarily mediated by the activation of the ubiquitin-proteasome syste
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d0c2b8a2a84b6d582b18894634e4ff5f
https://doi.org/10.1158/0008-5472.can-04-2102
https://doi.org/10.1158/0008-5472.can-04-2102