Zobrazeno 1 - 10
of 715
pro vyhledávání: '"A W, ADAMSON"'
Autor:
A. W. Adamson, Y. C. Ding, L. Steele, L. A. Leong, R. Morgan, M. T. Wakabayashi, E. S. Han, T. H. Dellinger, P. S. Lin, A. A. Hakim, S. Wilczynski, C. D. Warden, S. Tao, V. Bedell, M. C. Cristea, S. L. Neuhausen
Publikováno v:
Journal of Ovarian Research, Vol 16, Iss 1, Pp 1-14 (2023)
Abstract Background High-grade serous ovarian cancers (HGSCs) display a high degree of complex genetic alterations. In this study, we identified germline and somatic genetic alterations in HGSC and their association with relapse-free and overall surv
Externí odkaz:
https://doaj.org/article/a554d21176a142ac99996e2e44216fb8
Autor:
Alissa D. Clear, Glenn M. Manthey, Olivia Lewis, Isabelle Y. Lopez, Rossana Rico, Shannon Owens, M. Cristina Negritto, Elise W. Wolf, Jason Xu, Nikola Kenjić, J. Jefferson P. Perry, Aaron W. Adamson, Susan L. Neuhausen, Adam M. Bailis
Publikováno v:
Microbial Cell, Vol 7, Iss 10, Pp 270-285 (2020)
RAD52 is a structurally and functionally conserved component of the DNA double-strand break (DSB) repair apparatus from budding yeast to humans. We recently showed that expressing the human gene, HsRAD52 in rad52 mutant budding yeast cells can suppre
Externí odkaz:
https://doaj.org/article/84973d6299814b58baf88553703b7a68
Autor:
Aaron W. Adamson, Yuan Chun Ding, Carlos Mendez‐Dorantes, Adam M. Bailis, Jeremy M. Stark, Susan L. Neuhausen
Publikováno v:
Molecular Oncology, Vol 14, Iss 6, Pp 1124-1133 (2020)
Women who carry pathogenic mutations in BRCA1 and BRCA2 have a lifetime risk of developing breast cancer of up to 80%. However, risk estimates vary in part due to genetic modifiers. We investigated the association of the RAD52 S346X variant as a modi
Externí odkaz:
https://doaj.org/article/cb800f55b01b465182b712f608832d8f
Autor:
Yuan Chun Ding, Hanbing Song, Aaron W. Adamson, Daniel Schmolze, Donglei Hu, Scott Huntsman, Linda Steele, Carmina S. Patrick, Shu Tao, Natalie Hernandez, Charleen D. Adams, Laura Fejerman, Kevin Gardner, Anna María. Nápoles, Eliseo J. Perez-Stable, Jeffrey N. Weitzel, Henrik Bengtsson, Franklin W. Huang, Susan L. Neuhausen, Elad Ziv
Publikováno v:
Cancer Research.
Somatic mutational profiling is increasingly being used to identify potential targets for breast cancer. However, limited tumor-sequencing data from Hispanic/Latinas (H/L) are available to guide treatment. To address this gap, we performed whole exom
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::efed46387ef51b84c1bbb53afd835fe0
https://doi.org/10.1158/0008-5472.can-22-2510
https://doi.org/10.1158/0008-5472.can-22-2510
Autor:
Jovia L. Nierenberg, Aaron W. Adamson, Donglei Hu, Scott Huntsman, Carmina Patrick, Min Li, Linda Steele, Barry Tong, Yiwey Shieh, Laura Fejerman, Stephen B. Gruber, Christopher A. Haiman, Esther M. John, Lawrence H. Kushi, Gabriela Torres-Mejía, Charité Ricker, Jeffrey N. Weitzel, Elad Ziv, Susan L. Neuhausen
Publikováno v:
medRxiv
IntroductionBreast cancer (BC) is one of the most common cancers globally. Genetic testing can facilitate screening and risk-reducing recommendations, and inform use of targeted treatments. However, genes included in testing panels are from studies o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b541e13f99ef298c546e451f6b4bceff
https://europepmc.org/articles/PMC9901069/
https://europepmc.org/articles/PMC9901069/
Autor:
Emily M. Schmittel, Rachel F. Butterfras, Tracy Oliver, Cassandra G. Lettenberger-Klein, Darren W. Adamson
Publikováno v:
Contemporary Family Therapy
In response to the COVID-19 pandemic and a widespread shift to telehealth, there is an increased need to understand how we can best provide Telesupervision (TS). To help address the limited research on TS in the Marriage and family therapy (MFT) fiel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4fc41bc264b363bec9fee17ee0b001a4
http://europepmc.org/articles/PMC8346778
http://europepmc.org/articles/PMC8346778
Autor:
Yuan Chun Ding, Aaron W. Adamson, Mehrdad Bakhtiari, Carmina Patrick, Jonghun Park, Yael Laitman, Jeffrey N. Weitzel, Vineet Bafna, Eitan Friedman, Susan L. Neuhausen
Publikováno v:
European journal of human genetics : EJHG.
Despite substantial efforts in identifying both rare and common variants affecting disease risk, in the majority of diseases, a large proportion of unexplained genetic risk remains. We propose that variable number tandem repeats (VNTRs) may explain a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b09e949be61809bbdfe1bb26dda4dd41
https://pubmed.ncbi.nlm.nih.gov/36434258
https://pubmed.ncbi.nlm.nih.gov/36434258
Autor:
Frank M. Hilker, M. W. Adamson
Publikováno v:
Theoretical Ecology. 13:425-434
The monitoring of ecosystems and the spread of information concerning their state among human stakeholders is often a lengthy process. The importance of mutual feedbacks between socioeconomic and ecological dynamics is being increasingly recognised i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ab302b93285c1822168dce8e9d527508
https://doi.org/10.1007/s12080-020-00462-x
https://doi.org/10.1007/s12080-020-00462-x
Autor:
Maxwell Chirehwa, Katya Govender, Kogieleum Naidoo, Sinaye Ncgapu, Paolo Denti, Ravesh Singh, John W. Adamson, Nonhlanhla Yende-Zuma, Helen McIlleron, Nesri Padayatchi, Anushka Naidoo, Veron Ramsuran
Publikováno v:
Pharmacogenomics. 20:225-240
Aim: We report the prevalence and effect of genetic variability on pharmacokinetic parameters of isoniazid and rifampicin. Materials & methods: Genotypes for SLCO1B1, NAT2, PXR, ABCB1 and UGT1A genes were determined using a TaqMan® Genotyping OpenAr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cfef653446ab981495bcfe7cd449f518
https://doi.org/10.2217/pgs-2018-0166
https://doi.org/10.2217/pgs-2018-0166
Publikováno v:
PeerJ, Vol 2, p e600 (2014)
The Genome Analysis Toolkit (GATK) is commonly used for variant calling of single nucleotide polymorphisms (SNPs) and small insertions and deletions (indels) from short-read sequencing data aligned against a reference genome. There have been a number
Externí odkaz:
https://doaj.org/article/cdd20daad38f4345bf9a6dc528975f57