THERMAL HISTORY OF THE GULI PLUTON (NORTH OF THE SIBERIAN PLATFORM) ACCORDING TO APATITE FISSION-TRACK DATING AND COMPUTER MODELING

Autor: M. S. Myshenkova, V. A. Zaitsev, S. Thomson, A. V. Latyshev, V. S. Zakharov, T. E. Bagdasaryan, R. V. Veselovsky

Publikováno v: Геодинамика и тектонофизика, Vol 11, Iss 1, Pp 75-87 (2020)

We present the first results of fission-track dating of apatite monofractions from two rock samples taken from the Southern carbonatite massif of the world’s largest alkaline ultrabasic Guli pluton (~250 Ma), located within the Maymecha-Kotuy regio

Externí odkaz: https://doaj.org/article/48ebfb59066646eeb357814bb5b3f62f

New Positive TRPC6 Modulator Penetrates Blood–Brain Barrier, Eliminates Synaptic Deficiency and Restores Memory Deficit in 5xFAD Mice

Autor: Nikita Zernov, Alexander V. Veselovsky, Vladimir V. Poroikov, Daria Melentieva, Anastasia Bolshakova, Elena Popugaeva

Publikováno v: International Journal of Molecular Sciences, Vol 23, Iss 21, p 13552 (2022)

Synapse loss in the brain of Alzheimer’s disease patients correlates with cognitive dysfunctions. Drugs that limit synaptic loss are promising pharmacological agents. The transient receptor potential cation channel, subfamily C, member 6 (TRPC6) re

Externí odkaz: https://doaj.org/article/a022302d0f3245c9a3acb986e1246988

Hypersensitivity to Drug Excipients. Literature review

Autor: S. V. Zaikov, A. Ye. Bogomolov, N. A. Hritsova, L. V. Veselovsky

Publikováno v: Asthma and allergy. 2023:51-62

The article is devoted to an actual problem � the diagnosis of hypersensitivity to excipients that are the part of medicines. Hypersensitivity to drugs, the frequency of which is constantly increasing throughout the world, traditionally remains an

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::953b0b2da5d2657a54b3f8cdb24da2c5
https://doi.org/10.31655/2307-3373-2023-1-51-62

Enantiosective synthesis of a substituted cyclopentanone with all-carbon quaternary stereocenter

Autor: Antonina V. Lozanova, Andrei V. Stepanov, Mikhail V. Zlokazov, Vladimir V. Veselovsky

Publikováno v: ARKIVOC, Vol 2017, Iss 3, Pp 217-224 (2017)

Externí odkaz: https://doaj.org/article/2b0e3686bb384b8682b5f6a6e3de8351

A community effort to discover small molecule SARS-CoV-2 inhibitors

Autor: Johannes Schimunek, Philipp Seidl, Katarina Elez, Tim Hempel, Tuan Le, Frank Noé, Simon Olsson, Lluís Raich, Robin Winter, Hatice Gokcan, Filipp Gusev, Evgeny M. Gutkin, Olexandr Isayev, Maria G. Kurnikova, Chamali H. Narangoda, Roman Zubatyuk, Ivan P. Bosko, Konstantin V. Furs, Anna D. Karpenko, Yury V. Kornoushenko, Mikita Shuldau, Artsemi Yushkevich, Mohammed B. Benabderrahmane, Patrick Bousquet-Melou, Ronan Bureau, Beatrice Charton, Bertrand C. Cirou, Gérard Gil, William J. Allen, Suman Sirimulla, Stanley Watowich, Nick A. Antonopoulos, Nikolaos E. Epitropakis, Agamemnon K. Krasoulis, Vassilis P. Pitsikalis, Stavros T. Theodorakis, Igor Kozlovskii, Anton Maliutin, Alexander Medvedev, Petr Popov, Mark Zaretckii, Hamid Eghbal-zadeh, Christina Halmich, Sepp Hochreiter, Andreas Mayr, Peter Ruch, Michael Widrich, Francois Berenger, Ashutosh Kumar, Yoshihiro Yamanishi, Kam Y.J. Zhang, Emmanuel Bengio, Yoshua Bengio, Moksh J. Jain, Maksym Korablyov, Cheng-Hao Liu, Gilles Marcou, Enrico Glaab, Kelly Barnsley, Suhasini M. Iyengar, Mary Jo Ondrechen, V. Joachim Haupt, Florian Kaiser, Michael Schroeder, Luisa Pugliese, Simone Albani, Christina Athanasiou, Andrea Beccari, Paolo Carloni, Giulia D'Arrigo, Eleonora Gianquinto, Jonas Goßen, Anton Hanke, Benjamin P. Joseph, Daria B. Kokh, Sandra Kovachka, Candida Manelfi, Goutam Mukherjee, Abraham Muñiz-Chicharro, Francesco Musiani, Ariane Nunes-Alves, Giulia Paiardi, Giulia Rossetti, S. Kashif Sadiq, Francesca Spyrakis, Carmine Talarico, Alexandros Tsengenes, Rebecca C. Wade, Conner Copeland, Jeremiah Gaiser, Daniel R. Olson, Amitava Roy, Vishwesh Venkatraman, Travis J. Wheeler, Haribabu Arthanari, Klara Blaschitz, Marco Cespugli, Vedat Durmaz, Konstantin Fackeldey, Patrick D. Fischer, Christoph Gorgulla, Christian Gruber, Karl Gruber, Michael Hetmann, Jamie E. Kinney, Krishna M. Padmanabha Das, Shreya Pandita, Amit Singh, Georg Steinkellner, Guilhem Tesseyre, Gerhard Wagner, Zi-Fu Wang, Ryan J. Yust, Dmitry S. Druzhilovskiy, Dmitry A. Filimonov, Pavel V. Pogodin, Vladimir Poroikov, Anastassia V. Rudik, Leonid A. Stolbov, Alexander V. Veselovsky, Maria De Rosa, Giada De Simone, Maria R. Gulotta, Jessica Lombino, Nedra Mekni, Ugo Perricone, Arturo Casini, Amanda Embree, D. Benjamin Gordon, David Lei, Katelin Pratt, Christopher A. Voigt, Kuang-Yu Chen, Yves Jacob, Tim Krischuns, Pierre Lafaye, Agnès Zettor, M. Luis Rodríguez, Kris M. White, Daren Fearon, Frank Von Delft, Martin A. Walsh, Dragos Horvath, Charles L. Brooks III, Babak Falsafi, Bryan Ford, Adolfo García-Sastre, Sang Yup Lee, Nadia Naffakh, Alexandre Varnek, Günter Klambauer, Thomas M. Hermans

The COVID-19 pandemic continues to pose a substantial threat to human lives and is likely to do so for years to come. Despite the availability of vaccines, searching for efficient small-molecule drugs that are widely available, including in low- and

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::28010b1a0350f378ef0dcc633e87f6e1
https://doi.org/10.26434/chemrxiv-2023-1d5w8