Zobrazeno 1 - 10
of 141
pro vyhledávání: '"A V, Ulasov"'
Autor:
Rena T. Alieva, Alexey V. Ulasov, Yuri V. Khramtsov, Tatiana A. Slastnikova, Tatiana N. Lupanova, Maria A. Gribova, Georgii P. Georgiev, Andrey A. Rosenkranz
Publikováno v:
Pharmaceutics, Vol 16, Iss 8, p 1083 (2024)
Modular nanotransporters (MNTs) are drug delivery systems for targeted cancer treatment. As MNTs are composed of several modules, they offer the advantage of high specificity and biocompatibility in delivering drugs to the target compartment of cance
Externí odkaz:
https://doaj.org/article/2c82103088d248e5a39bdb051198dfe4
Autor:
Ilya V. Ulasov, Anton Borovjagin, Anastasia Laevskaya, Margarita Kamynina, Peter Timashev, Laura Cerchia, Elena A. Rozhkova
Publikováno v:
Genes and Diseases, Vol 10, Iss 1, Pp 89-100 (2023)
Glioblastoma (GBM) is one of the most aggressive (grade IV) gliomas characterized by a high rate of recurrence, resistance to therapy and a grim survival prognosis. The long-awaited improvement in GBM patients’ survival rates essentially depends on
Externí odkaz:
https://doaj.org/article/ca8cb4db658b469184f013dd6089abf9
Autor:
Yuri V. Khramtsov, Alexey V. Ulasov, Tatiana N. Lupanova, Tatiana A. Slastnikova, Andrey A. Rosenkranz, Egor S. Bunin, Georgii P. Georgiev, Alexander S. Sobolev
Publikováno v:
Pharmaceutics, Vol 16, Iss 1, p 4 (2023)
The proper viral assembly relies on both nucleic acids and structural viral proteins. Thus a biologically active agent that provides the degradation of one of these key proteins and/or destroys the viral factory could suppress viral replication effic
Externí odkaz:
https://doaj.org/article/9078efae66324ac392ec979fc1f31f15
Autor:
Yuri V. Khramtsov, Alexey V. Ulasov, Tatiana A. Slastnikova, Andrey A. Rosenkranz, Tatiana N. Lupanova, Georgii P. Georgiev, Alexander S. Sobolev
Publikováno v:
Pharmaceutics, Vol 15, Iss 12, p 2687 (2023)
Treatment of various diseases, in particular cancer, usually requires the targeting of biologically active molecules at a selected subcellular compartment. We modified our previously developed modular nanotransporters (MNTs) for targeting mitochondri
Externí odkaz:
https://doaj.org/article/2c59696d4c3e454db90c1b4a28b7bef3
Autor:
Andrey L. Istranov, Ivan G. Makarov, Natalya V. Makarova, Inna Tulina, Ilya V. Ulasov, Yuliya I. Isakova
Publikováno v:
Frontiers in Surgery, Vol 10 (2023)
ObjectiveGenital lymphedema is a severe, disabling condition associated with a malfunction of the lymphatic system. Primary lymphedema of the scrotum is a variant of congenital dysplasia of lymphatic vessels. Secondary genital lymphedema is much more
Externí odkaz:
https://doaj.org/article/8fe706b8700245839e39ccaac0c46894
Autor:
Simona Camorani, Margherita Passariello, Lisa Agnello, Silvia Esposito, Francesca Collina, Monica Cantile, Maurizio Di Bonito, Ilya V. Ulasov, Monica Fedele, Antonella Zannetti, Claudia De Lorenzo, Laura Cerchia
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 39, Iss 1, Pp 1-16 (2020)
Abstract Background Triple-negative breast cancer (TNBC) is a uniquely aggressive cancer with high rates of relapse due to resistance to chemotherapy. TNBC expresses higher levels of programmed cell death-ligand 1 (PD-L1) compared to other breast can
Externí odkaz:
https://doaj.org/article/911c06d557cc40be9d9119392620f362
Autor:
Yuri V. Khramtsov, Alexey V. Ulasov, Andrey A. Rosenkranz, Tatiana A. Slastnikova, Tatiana N. Lupanova, Georgii P. Georgiev, Alexander S. Sobolev
Publikováno v:
Pharmaceutics, Vol 15, Iss 2, p 324 (2023)
To compare the effectiveness of various bioactive agents reversibly acting within a cell on a target intracellular macromolecule, it is necessary to assess effective cytoplasmic concentrations of the delivered bioactive agents. In this work, based on
Externí odkaz:
https://doaj.org/article/1a5e4e2e128947acb79fceee227705e5
Autor:
Tatiana A. Slastnikova, Andrey A. Rosenkranz, Alexey V. Ulasov, Yuri V. Khramtsov, Tatiana N. Lupanova, Georgii P. Georgiev, Alexander S. Sobolev
Publikováno v:
Pharmaceutics, Vol 14, Iss 11, p 2448 (2022)
The development of epidermal growth factor receptor (EGFR)-targeting agents for the treatment of malignant melanoma requires cheap and easy animal tumor models for high-throughput in vivo screening. Thus, the aim of this study was to develop mouse sy
Externí odkaz:
https://doaj.org/article/f28fa7288514456fa6aced769df16676
Publikováno v:
Biomedicines, Vol 10, Iss 5, p 986 (2022)
Multiple efforts are currently underway to develop targeted therapeutic deliveries to the site of glioblastoma progression. The use of carriers represents advancement in the delivery of various therapeutic agents as a new approach in neuro-oncology.
Externí odkaz:
https://doaj.org/article/254c18d482ff4b7f917fb07f2ada0bfd
Autor:
Tatiana S. Karyagina, Alexey V. Ulasov, Tatiana A. Slastnikova, Andrey A. Rosenkranz, Tatiana N. Lupanova, Yuri V. Khramtsov, Georgii P. Georgiev, Alexander S. Sobolev
Publikováno v:
Frontiers in Pharmacology, Vol 11 (2020)
Since cell nucleus is one of the most vulnerable compartments, the maximum therapeutic effect from a variety of locally acting agents, such as photosensitizers, alfa-emitters, Auger electron emitters, will be expected when they get there. Therefore,
Externí odkaz:
https://doaj.org/article/3b46cb31443e4fd78a2e28d25090bf70