Zobrazeno 1 - 10
of 312
pro vyhledávání: '"A V, Spirin"'
Autor:
Sergey A. Dyshlovoy, Wael Y. Mansour, Natalia A. Ramm, Jessica Hauschild, Maxim E. Zhidkov, Malte Kriegs, Alexandra Zielinski, Konstantin Hoffer, Tobias Busenbender, Ksenia A. Glumakova, Pavel V. Spirin, Vladimir S. Prassolov, Derya Tilki, Markus Graefen, Carsten Bokemeyer, Gunhild von Amsberg
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-17 (2024)
Abstract Fascaplysin is a red cytotoxic pigment with anticancer properties isolated from the marine sponge Fascaplysinopsis sp. Recently, structure–activity relationship analysis reported by our group suggested that selective cytotoxicity of fascap
Externí odkaz:
https://doaj.org/article/df82a4dc141245f18a09fe909aa98ef5
Autor:
Alesya M. Mikheeva, Mikhail A. Bogomolov, Valentina A. Gasca, Mikhail V. Sementsov, Pavel V. Spirin, Vladimir S. Prassolov, Timofey D. Lebedev
Publikováno v:
Cell Death Discovery, Vol 10, Iss 1, Pp 1-11 (2024)
Abstract Imaging-based anticancer drug screens are becoming more prevalent due to development of automated fluorescent microscopes and imaging stations, as well as rapid advancements in image processing software. Automated cell imaging provides many
Externí odkaz:
https://doaj.org/article/b4b2da9c323f4178a43c92252caca866
Autor:
Oleg A. Tryapkin, Alexey V. Kantemirov, Sergey A. Dyshlovoy, Vladimir S. Prassolov, Pavel V. Spirin, Gunhild von Amsberg, Maria A. Sidorova, Maxim E. Zhidkov
Publikováno v:
Marine Drugs, Vol 21, Iss 8, p 424 (2023)
Fascaplysin is a marine alkaloid which is considered to be a lead drug candidate due to its diverse and potent biological activity. As an anticancer agent, fascaplysin holds a great potential due to the multiple targets affected by this alkaloid in c
Externí odkaz:
https://doaj.org/article/5a6439f52f024b4ba298586491177fd2
Publikováno v:
Кардиоваскулярная терапия и профилактика, Vol 18, Iss 5, Pp 90-97 (2019)
Aim. To evaluate the structure and predictors of vascular complications in Takayasu’s arteritis (TA) patients.Material and methods. Overall 183 TA patients have been treated at the Sverdlovsk Regional Clinical Hospital № 1 during the period from
Externí odkaz:
https://doaj.org/article/3854f0f2988849d5be7581182903afc5
Autor:
Yulia M. Grishaeva, Olga Yu. Matantseva, Iosif V. Spirin, Maria I. Savosina, Zinaida N. Tkacheva, Denis V. Vasin
Publikováno v:
Юг России: экология, развитие, Vol 13, Iss 4, Pp 24-46 (2019)
Aim. The aim is to reveal the need and relevant directions for the implementation of the concept of sustainable development in relation to the efficiency of transport and logistics activities. Methods. The methodology of research and development incl
Externí odkaz:
https://doaj.org/article/ce0a9312a7344f4fa4a793252d0a37e2
Autor:
Maxim E. Zhidkov, Moritz Kaune, Alexey V. Kantemirov, Polina A. Smirnova, Pavel V. Spirin, Maria A. Sidorova, Sergey A. Stadnik, Elena Y. Shyrokova, Dmitry N. Kaluzhny, Oleg A. Tryapkin, Tobias Busenbender, Jessica Hauschild, Tina Rohlfing, Vladimir S. Prassolov, Carsten Bokemeyer, Markus Graefen, Gunhild von Amsberg, Sergey A. Dyshlovoy
Publikováno v:
Marine Drugs, Vol 20, Iss 3, p 185 (2022)
Marine alkaloid fascaplysin and its derivatives are known to exhibit promising anticancer properties in vitro and in vivo. However, toxicity of these molecules to non-cancer cells was identified as a main limitation for their clinical use. Here, for
Externí odkaz:
https://doaj.org/article/67330185068f469f9bfc7ec7852d3d0f
Akademický článek
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Autor:
Irina Yu. Petrushanko, Vladimir A. Mitkevich, Valentina A. Lakunina, Anastasia A. Anashkina, Pavel V. Spirin, Peter M. Rubtsov, Vladimir S. Prassolov, Nikolay B. Bogdanov, Pascal Hänggi, William Fuller, Alexander A. Makarov, Anna Bogdanova
Publikováno v:
Redox Biology, Vol 13, Iss C, Pp 310-319 (2017)
Our previous findings suggested that reversible thiol modifications of cysteine residues within the actuator (AD) and nucleotide binding domain (NBD) of the Na,K-ATPase may represent a powerful regulatory mechanism conveying redox- and oxygen-sensiti
Externí odkaz:
https://doaj.org/article/070acd829be541699919a8f4371ce0b8
Publikováno v:
IEEE Transactions on Magnetics. 58:1-7
Autor:
Timofey D. Lebedev, Elmira R. Vagapova, Vladimir I. Popenko, Olga G. Leonova, Pavel V. Spirin, Vladimir S. Prassolov
Publikováno v:
Frontiers in Oncology, Vol 9 (2019)
Pediatric cancers represent a wide variety of different tumors, though they have unique features that distinguish them from adult cancers. Receptor tyrosine kinases KIT and TrkA functions in AML and NB, respectively, are well-characterized. Though ex
Externí odkaz:
https://doaj.org/article/0957f75265314e659be1679666207c8c