Zobrazeno 1 - 10
of 36
pro vyhledávání: '"A V, Sass"'
Autor:
Olga A. Rakitina, Alexey I. Kuzmich, Olga A. Bezborodova, Sofia A. Kondratieva, Victor V. Pleshkan, Marina V. Zinovyeva, Dmitry A. Didych, Aleksandr V. Sass, Eugene V. Snezhkov, Maria B. Kostina, Maksim O. Koksharov, Irina V. Alekseenko
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
BackgroundImmune checkpoint blockade (ICB) is rapidly becoming a standard of care in the treatment of many cancer types. However, the subset of patients who respond to this type of therapy is limited. Another way to promote antitumoral immunity is th
Externí odkaz:
https://doaj.org/article/d98d77adc9a749b981dd0cad1ef4f88c
Autor:
A. V. Sass, Irina V. Alekseenko, M. V. Zinovyeva, Dina V. Antonova, Victor V. Pleshkan, L. G. Kondratyeva
Publikováno v:
International Journal of Molecular Sciences
Volume 22
Issue 7
International Journal of Molecular Sciences, Vol 22, Iss 3298, p 3298 (2021)
Volume 22
Issue 7
International Journal of Molecular Sciences, Vol 22, Iss 3298, p 3298 (2021)
Cancer-associated fibroblasts (CAF) are attractive therapeutic targets in the tumor microenvironment. The possibility of using CAFs as a source of therapeutic molecules is a challenging approach in gene therapy. This requires transcriptional targetin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6aefb636ddfda2d7ae8ee06d7a4dd5f7
Autor:
Ilya V Demidyuk, Andrey V Shubin, Eugene V Gasanov, Alexander M Kurinov, Vladimir V Demkin, Tatyana V Vinogradova, Marina V Zinovyeva, Alexander V Sass, Irina B Zborovskaya, Sergey V Kostrov
Publikováno v:
PLoS ONE, Vol 8, Iss 2, p e55752 (2013)
Proprotein convertases (PCs) is a protein family which includes nine highly specific subtilisin-like serine endopeptidases in mammals. The system of PCs is involved in carcinogenesis and levels of PC mRNAs alter in cancer, which suggests expression s
Externí odkaz:
https://doaj.org/article/3a114ab15b0e433188c1c32db7f726d4
Autor:
A. V. Sass, A. V. Vvedensky, Lev G. Nikolaev, Eugene D. Sverdlov, M. V. Zinovyeva, V. K. Potapov
Publikováno v:
Molecular Genetics, Microbiology and Virology. 33:187-194
Naturally occurring positively charged proteins can be promising carriers for nucleic acid transport in gene therapy. The most attractive alternative among them is histones. In this work, we describe expression and purification of recombinant human h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e4874e154cf907d2d7208f5534ce48a0
https://doi.org/10.3103/s0891416818030072
https://doi.org/10.3103/s0891416818030072
Autor:
O. B. Filyukova, V. V. Pleshkan, E. V. Snezhkov, Eugene D. Sverdlov, A. V. Sass, I. V. Alekseenko
Publikováno v:
Doklady Biochemistry and Biophysics. 480:158-161
An artificial double tandem tumor-specific promoter based on survivin and human telomerase reverse transcriptase gene promoters was constructed. Studies in in vitro and ex vivo therapeutic systems showed that the designed promoter exhibits a high act
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9aeae8213bc08ea43e85ffbca26fdf67
https://doi.org/10.1134/s1607672918030092
https://doi.org/10.1134/s1607672918030092
Publikováno v:
Urology & Nephrology Open Access Journal. 8:114-115
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f9f910cee8fd422ebb8610ec8474f1c5
https://doi.org/10.15406/unoaj.2020.08.00287
https://doi.org/10.15406/unoaj.2020.08.00287
Publikováno v:
Human gene therapy methods. 28(5)
A set of vectors for Cre recombinase-dependent expression of the hybrid suicidal FCU1 transgene was constructed, including a two-plasmid system wherein the FCU1 and Cre transgenes reside in separate vectors, and single-plasmid variants in which a sin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e1ec9da2e90d64606bba2cfb5eea8ad4
https://pubmed.ncbi.nlm.nih.gov/28446024
https://pubmed.ncbi.nlm.nih.gov/28446024
Autor:
L. V. Dergunova, I. B. Zborovskaya, Svetlana A. Limborska, M. V. Zinovyeva, A. V. Sass, Alexandra V. Rozhkova
Publikováno v:
Molecular Biology. 48:340-346
The investigation of molecular mechanisms contributing to cancer progression is the burning problem of current research. Considerable attention has been focused on the study of gene expression in cancer cells. Sphingomyelin synthase 1 gene (SGMS1) is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fb0a69dd296cfc0a1b6e84c3334ef6af
https://doi.org/10.1134/s0026893314030170
https://doi.org/10.1134/s0026893314030170
Autor:
M. V. Zinovyeva, Ilya V. Demidyuk, Sergey V. Kostrov, Andrey V. Shubin, Demkin Vv, A. V. Sass, I. B. Zborovskaya, A. M. Kurinov, Tatyana V. Vinogradova
Publikováno v:
Biomarkers. 15:608-613
Objectives: Lysosomal proteases cathepsins B and D (CB and CD) play a significant part in cancer progression. For many oncological diseases protein expression levels of CB and CD have been investigated and correlations with tumour characteristics rev
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::60b1c047dfa75c46b530d27f6d0e1931
https://doi.org/10.3109/1354750x.2010.504310
https://doi.org/10.3109/1354750x.2010.504310
Autor:
A. V. Sass, E. P. Kopantzev, R. N. Mingaleeva, Eugene D. Sverdlov, Igor P. Chernov, L. L. Zavalova
Publikováno v:
Molecular Biology. 44:448-453
Tumor-specific promoters are predominantly active and ensure expression of the gene under control exclusively in cancer cells. However, low activity of the promoters is an essential disadvantage for their therapy usage. To achieve a higher expression
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0fc6fc7ad9a9ad9c6a91fba0e63436f3
https://doi.org/10.1134/s0026893310030131
https://doi.org/10.1134/s0026893310030131