Zobrazeno 1 - 10
of 256
pro vyhledávání: '"A V, Feofanov"'
Autor:
Daria K. Malinina, Grigoriy A. Armeev, Olga V. Geraskina, Anna N. Korovina, Vasily M. Studitsky, Alexey V. Feofanov
Publikováno v:
Biomolecules, Vol 14, Iss 9, p 1184 (2024)
Saccharomyces cerevisiae HMO1 is an architectural nuclear DNA-binding protein that stimulates the activity of some remodelers and regulates the transcription of ribosomal protein genes, often binding to a DNA motif called IFHL. However, the molecular
Externí odkaz:
https://doaj.org/article/cf162ce9ed68484f9505afe6a5f42cee
Autor:
Pavel D. Oleinikov, Anastasiia S. Fedulova, Grigoriy A. Armeev, Nikita A. Motorin, Lovepreet Singh-Palchevskaia, Anastasiia L. Sivkina, Pavel G. Feskin, Grigory S. Glukhov, Dmitry A. Afonin, Galina A. Komarova, Mikhail P. Kirpichnikov, Vasily M. Studitsky, Alexey V. Feofanov, Alexey K. Shaytan
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 20, p 15194 (2023)
In eukaryotic organisms, genomic DNA associates with histone proteins to form nucleosomes. Nucleosomes provide a basis for genome compaction, epigenetic markup, and mediate interactions of nuclear proteins with their target DNA loci. A negatively cha
Externí odkaz:
https://doaj.org/article/9b965cc0c6d34e5693fede8ba273795d
Autor:
Tatiana V. Andreeva, Natalya V. Maluchenko, Anastasiya V. Efremenko, Alexander V. Lyubitelev, Anna N. Korovina, Dmitry A. Afonin, Mikhail P. Kirpichnikov, Vasily M. Studitsky, Alexey V. Feofanov
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 18, p 14187 (2023)
The natural flavonoid epigallocatechin gallate has a wide range of biological activities, including being capable of binding to nucleic acids; however, the mechanisms of the interactions of epigallocatechin gallate with DNA organized in chromatin hav
Externí odkaz:
https://doaj.org/article/37749248e6874c0996f3ea4b70cdcf3d
Autor:
Anastasiia L. Sivkina, Maria G. Karlova, Maria E. Valieva, Laura L. McCullough, Timothy Formosa, Alexey K. Shaytan, Alexey V. Feofanov, Mikhail P. Kirpichnikov, Olga S. Sokolova, Vasily M. Studitsky
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-9 (2022)
Sivkina et al. present a biochemical and biophysical characterization of the interaction of S. cerevisiae histone chaperone FACT with the nucleosome core particle. They show that FACT adopts a more open geometry in the presence of Nhp6, and together
Externí odkaz:
https://doaj.org/article/a6b17f84681e4269915f8db9da80afb0
Autor:
Maria E. Stefanova, Olesya I. Volokh, Oleg V. Chertkov, Grigory A. Armeev, Alexey K. Shaytan, Alexey V. Feofanov, Mikhail P. Kirpichnikov, Olga S. Sokolova, Vasily M. Studitsky
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 15, p 12127 (2023)
Formation of compact dinucleosomes (CODIs) occurs after collision between adjacent nucleosomes at active regulatory DNA regions. Although CODIs are likely dynamic structures, their structural heterogeneity and dynamics were not systematically address
Externí odkaz:
https://doaj.org/article/55f47314e3ad4dcdb8917a8b2f3565ad
Autor:
Nikita A. Orlov, Elena V. Kryukova, Anastasia V. Efremenko, Sergey A. Yakimov, Victoria A. Toporova, Mikhail P. Kirpichnikov, Oksana V. Nekrasova, Alexey V. Feofanov
Publikováno v:
Membranes, Vol 13, Iss 7, p 645 (2023)
The voltage-gated potassium channel Kv1.1, which is abundant in the CNS and peripheral nervous system, controls neuronal excitability and neuromuscular transmission and mediates a number of physiological functions in non-excitable cells. The developm
Externí odkaz:
https://doaj.org/article/cfb44605bfc640008fec3610b2320174
Autor:
Alexandra L. Primak, Nikita A. Orlov, Steve Peigneur, Jan Tytgat, Anastasia A. Ignatova, Kristina R. Denisova, Sergey A. Yakimov, Mikhail P. Kirpichnikov, Oksana V. Nekrasova, Alexey V. Feofanov
Publikováno v:
Toxins, Vol 15, Iss 3, p 229 (2023)
The growing interest in potassium channels as pharmacological targets has stimulated the development of their fluorescent ligands (including genetically encoded peptide toxins fused with fluorescent proteins) for analytical and imaging applications.
Externí odkaz:
https://doaj.org/article/98a6a2fd89be41559e83da7da2cff6be
Autor:
Maria A. Ovcharova, Mikhail I. Schelkunov, Olga V. Geras’kina, Nadezhda E. Makarova, Marina V. Sukhacheva, Sergey V. Martyanov, Ekaterina D. Nevolina, Marina V. Zhurina, Alexey V. Feofanov, Ekaterina A. Botchkova, Vladimir K. Plakunov, Andrei V. Gannesen
Publikováno v:
Biology, Vol 12, Iss 3, p 436 (2023)
The effect of C-type natriuretic peptide in a concentration closer to the normal level in human blood plasma was studied on the mono-species and dual-species biofilms of the skin commensal bacteria Cutibacterium acnes HL043PA2 and Staphylococcus epid
Externí odkaz:
https://doaj.org/article/1fb84691d2794b4aa4774087c85cb56a
Autor:
Marina A. Pavlova, Pavel A. Panchenko, Ekaterina A. Alekhina, Anastasia A. Ignatova, Anna D. Plyutinskaya, Andrey A. Pankratov, Dmitriy A. Pritmov, Mikhail A. Grin, Alexey V. Feofanov, Olga A. Fedorova
Publikováno v:
Biosensors, Vol 12, Iss 12, p 1149 (2022)
Herein, we report a new conjugate BChl–S–S–NI based on the second-generation photosensitizer bacteriochlorin e6 (BChl) and a 4-styrylnaphthalimide fluorophore (NI), which is cleaved into individual functional fragments in the intracellular medi
Externí odkaz:
https://doaj.org/article/83f34101fc72466981e2c6289f60356a
Autor:
Nikita A. Orlov, Anastasia A. Ignatova, Elena V. Kryukova, Sergey A. Yakimov, Mikhail P. Kirpichnikov, Oksana V. Nekrasova, Alexey V. Feofanov
Publikováno v:
Toxins, Vol 14, Iss 12, p 858 (2022)
The voltage-gated potassium Kv1.3 channel is an essential component of vital cellular processes which is also involved in the pathogenesis of some autoimmune, neuroinflammatory and oncological diseases. Pore blockers of the Kv1.3 channel are consider
Externí odkaz:
https://doaj.org/article/2905dd7e5aa7467a9870eac99fe0995e