Zobrazeno 1 - 10
of 49
pro vyhledávání: '"A V, Cope"'
Autor:
Avinash Aujayeb, Rachel Prichard, S Park, Mark A Baxter, J Hamilton, H Ali, L Hannington, Conor O'Neill, J Platt, G Clements, Deborah Scott, R Heywood, Helen Dearden, Sally Martin, Michael Rowe, Kieran Zucker, Clair Brunner, Adam L Peters, Maria Rohan, Alexandra Marsh, Abigail L Gee, Gemma Quesne, Jonny Heseltine, Joni Howells, Veronica Conteh, Xiangfei Yan, Lisa J Rodgers, J Grech, S McInerney, S Kingdon, L Eastlake, R Bryce, D Parslow, V Cope, N Aziz
Publikováno v:
BMJ Oncology, Vol 3, Iss 1 (2024)
Objective The Cancer and Aging Research Group (CARG) score was developed to predict severe chemotherapy-induced toxicity risk in older adults; validation study results have varied. The Tolerance of Anti-cancer Systemic Therapy in the Elderly study so
Externí odkaz:
https://doaj.org/article/30744de9a2794c768c87e2ba9b482a00
Autor:
G. Haidari, Suzanne Day, M. Wood, H. Ridgers, Alethea V. Cope, Sue Fleck, Celine Yan, Kalevi Reijonen, Drew Hannaman, Aggeliki Spentzou, Peter Hayes, A. Vogt, Behazine Combadiere, Adrian Cook, Sheena McCormack, Robin J. Shattock
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Previous studies have shown targeting different tissues via the transcutaneous (TC) and intramuscular injection (IM) with or without electroporation (EP) has the potential to trigger immune responses to DNA vaccination. The CUTHIVTHER 001 Phase I/II
Externí odkaz:
https://doaj.org/article/639425c1542e4f4f8947fea60d34f713
Autor:
Yuka Nadai, Kathrin Held, Sarah Joseph, Mohamed I. M. Ahmed, Verena S. Hoffmann, David Peterhoff, Marco Missanga, Asli Bauer, Agricola Joachim, Ulf Reimer, Johannes Zerweck, Sheena McCormack, Alethea V. Cope, Roger Tatoud, Robin J. Shattock, Merlin Lee Robb, Eric G. Sandstroem, Michael Hoelscher, Leonard Maboko, Muhammad Bakari, Arne Kroidl, Ralf Wagner, Jonathan Weber, Georgios Pollakis, Christof Geldmacher
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Background: A better understanding of the parameters influencing vaccine-induced IgG recognition of individual antigenic regions and their variants within the HIV Envelope protein (Env) can help to improve design of preventive HIV vaccines.Methods: E
Externí odkaz:
https://doaj.org/article/018bd7b14ff04ec3a2e5a1319f5b7658
Autor:
Victoria M. W. Gould, James N. Francis, Katie J. Anderson, Bertrand Georges, Alethea V. Cope, John S. Tregoning
Publikováno v:
Frontiers in Microbiology, Vol 8 (2017)
In spite of there being a number of vaccines, influenza remains a significant global cause of morbidity and mortality. Understanding more about natural and vaccine induced immune protection against influenza infection would help to develop better vac
Externí odkaz:
https://doaj.org/article/fa67bd1e386a4a838b408175937f17bf
Autor:
Catherine A Cosgrove, Charles J Lacey, Alethea V Cope, Angela Bartolf, Georgina Morris, Celine Yan, Susan Baden, Tom Cole, Darrick Carter, Elizabeth Brodnicki, Xiaoying Shen, Sarah Joseph, Stephen C DeRosa, Lili Peng, Xuesong Yu, Guido Ferrari, Mike Seaman, David C Montefiori, Nicole Frahm, Georgia D Tomaras, Wolfgang Stöhr, Sheena McCormack, Robin J Shattock
Publikováno v:
PLoS ONE, Vol 11, Iss 5, p e0152038 (2016)
BackgroundDefining optimal routes for induction of mucosal immunity represents an important research priority for the HIV-1 vaccine field. In particular, it remains unclear whether mucosal routes of immunization can improve mucosal immune responses.M
Externí odkaz:
https://doaj.org/article/08ec5605bc8444f7b1cb6ed38f6f0216
Autor:
Paul F McKay, Alethea V Cope, Jamie F S Mann, Sarah Joseph, Mariano Esteban, Roger Tatoud, Darrick Carter, Steven G Reed, Jonathan Weber, Robin J Shattock
Publikováno v:
PLoS ONE, Vol 9, Iss 1, p e84707 (2014)
Using a unique vaccine antigen matched and single HIV Clade C approach we have assessed the immunogenicity of a DNA-poxvirus-protein strategy in mice and rabbits, administering MVA and protein immunizations either sequentially or simultaneously and i
Externí odkaz:
https://doaj.org/article/ca98186953624a2f81e4dea373d08f15
Autor:
J. Gambrill, S. Moore, J. Newbury, Geoffrey A. Donnan, Marilyn McMurchie, F. Boyle, David A Gleave, A. Bruce, Christopher A Silagy, B. McDermott, P. Fletcher, Mark Brown, Stephen MacMahon, Colin I. Johnston, Stephen B. Harrap, Leon Piterman, Jonathan R. Thompson, Paul Glasziou, Michael P. Feneley, P. Webb, Kristyn Willson, J. A. Whitworth, C. Bear, P. Beckinsale, J. Primrose, C. Dibben, John R. Moss, Enayet K. Chowdhury, Lindon M H Wing, F. De Looze, Garry L. Jennings, Fred DeLooze, Je Marley, Philip Joseph, Trefor Morgan, Jan E. Dickinson, V. Cope, Mark Nelson, Elizabeth M Dewar, Philip Ryan, Lawrence J. Beilin, G. Fraser, Christopher M. Reid
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Background Information is scarce regarding effects of antihypertensive medication on blood pressure variability ( BPV ) and associated clinical outcomes. We examined whether antihypertensive treatment changes BPV over time and whether such change (de
Autor:
Carol V. Cope, Janice Derr, Karyn D. Howard, Joseph C. Kawalek, Michael J. Myers, Dorothy E. Farrell, Jean D. Jackson
Publikováno v:
American Journal of Veterinary Research. 64:1167-1175
Objective—To determine the effect of oral administration of low doses of pentobarbital on cytochrome P450 (CYP) isoforms and CYP-mediated reactions in immature Beagles. Animals—42 immature (12-week-old) Beagles. Procedure—Dogs were grouped and
Publikováno v:
Journal of Pharmacology and Experimental Therapeutics. 304:889-895
The impact of Escherichia coli-derived lipopolysaccharide (LPS) on the pharmacokinetic parameters of enrofloxacin in swine was assessed to determine whether this model would substitute for a pleuropneumonia infection model for pharmacokinetic evaluat
Autor:
M. P. Landini, Ak Burroughs, Keith Rolles, J. Wise, Gregory T. Maine, Tiziana Lazzarotto, Vincent C. Emery, Caroline A. Sabin, Susan Brojanac, A. V. Cope
Publikováno v:
The Journal of Infectious Diseases. 182:1610-1615
A retrospective study was performed on a selected cohort of 40 liver transplant recipients derived from the previous prospective follow-up of 162 liver transplant patients. The criterion for selection of this cohort was the presence of human cytomega