Zobrazeno 1 - 10
of 36
pro vyhledávání: '"A V, Azaryan"'
Publikováno v:
Canadian Journal of Physiology and Pharmacology. 76:278-283
Chronic continuous cocaine administration for 3 days has been shown to upregulate the level of µ opioid receptor (MOR) mRNA in the nucleus accumbens (n. acc.) of rat brain. Dopamine (DA) antagonists, SCH 23390, eticlopride, and nafadotride, blocked,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5ba097ae1a2ae070dd5df6bde786cba2
https://doi.org/10.1139/y98-023
https://doi.org/10.1139/y98-023
Publikováno v:
Pharmaceutical Chemistry Journal. 32:55-58
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7ea5ed2b55ae12c363b68d895b32bee8
https://doi.org/10.1007/bf02464161
https://doi.org/10.1007/bf02464161
Autor:
Andrea B. Kohn, Anahit V. Azaryan, Kurt W. Miller, Vivian Hook, Kim Moran, Martin R. Schiller, Mark O. Lively, Rama Kannan
Publikováno v:
Protein Expression and Purification. 10:80-88
Prohormone substrates are required for investigation of the proteolytic processing of prohormones and proproteins into active peptide hormones and neurotransmitters. However, the lack of prohormone proteins has been a limiting factor in elucidating p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f27cc76db1f8d880f9981c995f0d2e4
https://doi.org/10.1006/prep.1996.0715
https://doi.org/10.1006/prep.1996.0715
Publikováno v:
Neurochemical Research. 21:1411-1415
We have previously demonstrated that continuous cocaine treatment for three days induces a marked but transient increase in mu opioid receptor (MOR) mRNA in nucleus accumbens (n. acc.); SCH 23390 and eticlopride, selective antagonists of D1- and D2-l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b7e9e44d950b5347ff3300e553a1b2d
https://doi.org/10.1007/bf02532382
https://doi.org/10.1007/bf02532382
Publikováno v:
Annals of the New York Academy of Sciences. 780:121-133
Our discovery of precursor preference of processing enzymes indicates possible development of future drugs that target specific proteases uniquely associated associated with processing of a particular prohormone. For example, selective processing of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c941ad15d62c59264ebf5f1762c6efd0
https://doi.org/10.1111/j.1749-6632.1996.tb15116.x
https://doi.org/10.1111/j.1749-6632.1996.tb15116.x
Publikováno v:
Biochemical and Biophysical Research Communications. 215:937-944
Our search for proteases responsible for proenkephalin (PE) processing in adrenal medulla led to the isolation of a 70 kDa aspartic proteinase that cleaves PE between the basic residues of the Lys-Arg processing site (1). Studies in pituitary have al
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d67078ac1352d341b8f22c8535afb806
https://doi.org/10.1006/bbrc.1995.2554
https://doi.org/10.1006/bbrc.1995.2554
Publikováno v:
Journal of Biological Chemistry. 270:8201-8208
The prohormone-processing proteases PC1/3 and PC2 belong to the family of mammalian subtilisin-related proprotein convertases (PC) possessing homology to the yeast Kex2 protease. The presence of PC1/3 and PC2 in secretory vesicles of bovine adrenal m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::113de3bfa7bdc2fde6e76302a53498f6
https://doi.org/10.1074/jbc.270.14.8201
https://doi.org/10.1074/jbc.270.14.8201
Publikováno v:
Chemistry of Heterocyclic Compounds. 31:28-32
A simple method is proposed for synthesizing 1-carbamoyl-2-pyrrolidones by cyclization of 4-ureidobutanoic acids in acetic anhydride.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c531f99ef922da1d92ee7f743d5f7722
https://doi.org/10.1007/bf01171285
https://doi.org/10.1007/bf01171285
Publikováno v:
Journal of Biological Chemistry. 268:20570-20577
Evidence is presented showing that alpha 1-antichymotrypsin (ACT) inhibits a novel prohormone thiol protease (PTP) involved in processing the enkephalin precursor. Colocalization of ACT immunoreactivity with PTP within isolated secretory vesicles of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c45f2adc2e77cb4c1738bc82eae7745d
https://doi.org/10.1016/s0021-9258(20)80763-7
https://doi.org/10.1016/s0021-9258(20)80763-7
Autor:
Niamh X. Cawley, Y P Loh, F E Estivariz, Theodore C. Friedman, M Wong, Huaxian Chen, A. V. Azaryan
Publikováno v:
Journal of Biological Chemistry. 268:11968-11975
Yeast cells express an alternate enzyme encoded by the YAP3 gene which can process pro-alpha-mating factor when this pheromone is overexpressed in KEX2-deficient mutants. The YAP3 gene product is an aspartic protease (YAP3) that cleaves at paired bas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9f6d8785e0c47d3fcf690ee8396f0b54
https://doi.org/10.1016/s0021-9258(19)50295-2
https://doi.org/10.1016/s0021-9258(19)50295-2