Zobrazeno 1 - 10
of 14
pro vyhledávání: '"A Trey Belew"'
Autor:
A Trey Belew, Caroline Junqueira, Gabriela F Rodrigues-Luiz, Bruna M Valente, Antonio Edson R Oliveira, Rafael B Polidoro, Luciana W Zuccherato, Daniella C Bartholomeu, Sergio Schenkman, Ricardo T Gazzinelli, Barbara A Burleigh, Najib M El-Sayed, Santuza M R Teixeira
Publikováno v:
PLoS Pathogens, Vol 13, Iss 12, p e1006767 (2017)
Trypanosoma cruzi, the protozoan that causes Chagas disease, has a complex life cycle involving several morphologically and biochemically distinct stages that establish intricate interactions with various insect and mammalian hosts. It has also a het
Externí odkaz:
https://doaj.org/article/df2f52e5214441558cf3b85fe8452752
Autor:
Yuan Li, Sheena Shah-Simpson, Kwame Okrah, A Trey Belew, Jungmin Choi, Kacey L Caradonna, Prasad Padmanabhan, David M Ndegwa, M Ramzi Temanni, Héctor Corrada Bravo, Najib M El-Sayed, Barbara A Burleigh
Publikováno v:
PLoS Pathogens, Vol 12, Iss 4, p e1005511 (2016)
Intracellular colonization and persistent infection by the kinetoplastid protozoan parasite, Trypanosoma cruzi, underlie the pathogenesis of human Chagas disease. To obtain global insights into the T. cruzi infective process, transcriptome dynamics w
Externí odkaz:
https://doaj.org/article/64b098f26aac404f98716b062479c8bd
Publikováno v:
PLoS ONE, Vol 11, Iss 8, p e0159197 (2016)
Trypanosoma cruzi, the causative agent of Chagas Disease, is phylogeneticaly distributed into nearly identical genetic strains which show divergent clinical presentations including differences in rates of cardiomyopathy in humans, different vector sp
Externí odkaz:
https://doaj.org/article/7848bb71871b4f0995621b2505638717
Autor:
Deninson Alejandro Vargas, David J. Gregory, Roni Nitzan Koren, Dan Zilberstein, Ashton Trey Belew, Najib M. El-Sayed, María Adelaida Gómez
Publikováno v:
Frontiers in Parasitology, Vol 2 (2023)
Host cell functions that participate in the pharmacokinetics and pharmacodynamics (PK/PD) of drugs against intracellular pathogen infections are critical for drug efficacy. In this study, we investigated whether macrophage mechanisms of xenobiotic de
Externí odkaz:
https://doaj.org/article/3a3e86c308f74579b3e15cd09ab1ca59
Autor:
Maria Adelaida Gomez, Ashton Trey Belew, Adriana Navas, Mariana Rosales-Chilama, Julieth Murillo, Laura A. L. Dillon, Theresa A. Alexander, Alvaro Martinez-Valencia, Najib M. El-Sayed
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 11 (2021)
Early host-pathogen interactions drive the host response and shape the outcome of natural infections caused by intracellular microorganisms. These interactions involve a number of immune and non-immune cells and tissues, along with an assortment of h
Externí odkaz:
https://doaj.org/article/ff4683e6cbf740a4babeead0373c1464
Autor:
Renan Garcia de Moura, Luciana Polaco Covre, Carlos Henrique Fantecelle, Vitor Alejandro Torres Gajardo, Carla Baroni Cunha, Lorenzzo Lyrio Stringari, Ashton Trey Belew, Camila Batista Daniel, Sandra Ventorin Von Zeidler, Carlos Eduardo Tadokoro, Herbert Leonel de Matos Guedes, Raphael Lubiana Zanotti, David Mosser, Aloisio Falqueto, Arne N. Akbar, Daniel Claudio Oliveira Gomes
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Patients infected by Leishmania braziliensis develop debilitating skin lesions. The role of inhibitory checkpoint receptors (ICRs) that induce T cell exhaustion during this disease is not known. Transcriptional profiling identified increased expressi
Externí odkaz:
https://doaj.org/article/d7475f9b3d034bcb940bc04b036e221c
Autor:
Solomon A. Mekonnen, Nour El Husseini, Asan Turdiev, Jared A. Carter, Ashton Trey Belew, Najib M. El-Sayed, Vincent T. Lee
Publikováno v:
Proceedings of the National Academy of Sciences. 119
Healthcare-associated infections are major causes of complications that lead to extended hospital stays and significant medical costs. The use of medical devices, including catheters, increases the risk of bacterial colonization and infection through
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Publikováno v:
PLoS ONE, Vol 11, Iss 8, p e0159197 (2016)
PLoS ONE
PLoS ONE
Trypanosoma cruzi, the causative agent of Chagas Disease, is phylogeneticaly distributed into nearly identical genetic strains which show divergent clinical presentations including differences in rates of cardiomyopathy in humans, different vector sp
Autor:
Rahul Suresh, Héctor Corrada Bravo, Najib M. El-Sayed, Laura A. L. Dillon, Kwame Okrah, V. Keith Hughitt, Yuan Li, A. Trey Belew, Maria Cecilia Fernandes, David M. Mosser
Publikováno v:
Nucleic Acids Research
Protozoan parasites of the genus Leishmania are the etiological agents of leishmaniasis, a group of diseases with a worldwide incidence of 0.9-1.6 million cases per year. We used RNA-seq to conduct a high-resolution transcriptomic analysis of the glo