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pro vyhledávání: '"A T Transue"'
Autor:
Amy T. Transue, Donna M. Harsh, Ronald J. Hessler, James E. Smolen, Ruth C. Brower, Sima Zacharek, R. Alexander Blackwood
Publikováno v:
Journal of Leukocyte Biology. 59:663-670
Neutrophil stimulation results in the activation of a variety of phospholipases, including phospholipase A2 (PLA2), which releases arachidonic acid from the 2 position of membrane phospholipids, leaving a lysophospholipid. Because arachidonic acid is
Autor:
S. French, A T Transue, Donna M. Harsh, James E. Smolen, R. C. Brower, Ronald J. Hessler, R A Blackwood
Publikováno v:
The American journal of physiology. 272(4 Pt 1)
Phospholipase D (PLD) activation in stimulated neutrophils results in the conversion of membrane phosphatidylcholine (PC) to phosphatidic acid (PA). This change in membrane phospholipid composition has two potentially positive effects on degranulatio
Publikováno v:
Journal of leukocyte biology. 60(1)
During inflammation neutrophils receive multiple signals that are integrated, allowing a single modified response. One mechanism for this discrimination is receptor desensitization, a process whereby ligand-receptor binding is disassociated from cell