Zobrazeno 1 - 10
of 81
pro vyhledávání: '"A T Fabro"'
Autor:
Rafael R. Ferreira, Ronaldo B. Martins, Isabela Pires, Bruno L. Marques, Karla C.M. Costa, Pedro H.C. Lirio, Davi S. Scomparin, Franciele F. Scarante, Sabrina S. Batah, Jaime E.C. Hallak, Jose A. Crippa, Livia C.M. Rodrigues, Rita C. Tostes, Alexandre T. Fabro, Eurico Arruda, Alline C. Campos
Publikováno v:
Brain, Behavior, & Immunity - Health, Vol 41, Iss , Pp 100855- (2024)
Even though respiratory dysfunctions are the primary symptom associated with SARS-CoV-2 infection, cerebrovascular events, and neurological symptoms are described in many patients. However, the connection between the neuroimmune profile and the lung'
Externí odkaz:
https://doaj.org/article/cf285cdcd235496ba2909cf86e220320
Autor:
Keyla S G de Sá, Luana A Amaral, Tamara S Rodrigues, Camila C S Caetano, Amanda Becerra, Sabrina S Batah, Felipe T Lopes, Isadora M de Oliveira, Letícia S Lopes, Leticia Almeida, Caroline M Mota, Samuel Oliveira, Danilo T Wada, Marcel Koenigkam-Santos, Ronaldo B Martins, Roberta R C Rosales, Eurico Arruda, Alexandre T Fabro, Dario S Zamboni
Publikováno v:
PLoS Pathogens, Vol 20, Iss 6, p e1012222 (2024)
COVID-19 has affected more than half a billion people worldwide, with more than 6.3 million deaths, but the pathophysiological mechanisms involved in lethal cases and the host determinants that determine the different clinical outcomes are still uncl
Externí odkaz:
https://doaj.org/article/eaf6eb7e94f3467683d58b1f62c481e8
Autor:
Flavio P. Veras, Giovanni F. Gomes, Bruna M. S. Silva, Diego B. Caetité, Cicero J. L. R. Almeida, Camila Meirelles S. Silva, Ayda H. Schneider, Emily S. Corneo, Caio S. Bonilha, Sabrina S. Batah, Ronaldo Martins, Eurico Arruda, Alexandre T. Fabro, José C. Alves-Filho, Thiago M. Cunha, Fernando Q. Cunha
Publikováno v:
Respiratory Research, Vol 24, Iss 1, Pp 1-11 (2023)
Abstract Background COVID-19 is characterized by severe acute lung injury, which is associated with neutrophil infiltration and the release of neutrophil extracellular traps (NETs). COVID-19 treatment options are scarce. Previous work has shown an in
Externí odkaz:
https://doaj.org/article/4e2c272fc010424eb6725b2efe746055
Autor:
Keyla S. G. de Sá, Luana A. Amaral, Tamara S. Rodrigues, Adriene Y. Ishimoto, Warrison A. C. de Andrade, Leticia de Almeida, Felipe Freitas-Castro, Sabrina S. Batah, Sergio C. Oliveira, Mônica T. Pastorello, Alexandre T. Fabro, Dario S. Zamboni
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-19 (2023)
Here, de Sá et al. show that Gasdermin-D is transiently activated in Leishmania-infected macrophages and promotes NLRP3 inflammasome activation, but not cell death. Gasdermin-D is cleaved into a noncanonical fragment, indicating that Leishmania subv
Externí odkaz:
https://doaj.org/article/1a83c20a305e4205a732e3e7fc4d594d
Autor:
Bruna M. Silva, Giovanni F. Gomes, Flavio P. Veras, Seppe Cambier, Gabriel V.L. Silva, Andreza U. Quadros, Diego B. Caetité, Daniele C. Nascimento, Camilla M. Silva, Juliana C. Silva, Samara Damasceno, Ayda H. Schneider, Fabio Beretta, Sabrina S. Batah, Icaro M.S. Castro, Isadora M. Paiva, Tamara Rodrigues, Ana Salina, Ronaldo Martins, Guilherme C.M. Cebinelli, Naira L. Bibo, Daniel M. Jorge, Helder I. Nakaya, Dario S. Zamboni, Luiz O. Leiria, Alexandre T. Fabro, José C. Alves-Filho, Eurico Arruda, Paulo Louzada-Junior, Renê D. Oliveira, Larissa D. Cunha, Pierre Van Mol, Lore Vanderbeke, Simon Feys, Els Wauters, Laura Brandolini, Andrea Aramini, Fernando Q. Cunha, Jörg Köhl, Marcello Allegretti, Diether Lambrechts, Joost Wauters, Paul Proost, Thiago M. Cunha
Publikováno v:
The Journal of Clinical Investigation, Vol 133, Iss 12 (2023)
Patients with severe COVID-19 develop acute respiratory distress syndrome (ARDS) that may progress to cytokine storm syndrome, organ dysfunction, and death. Considering that complement component 5a (C5a), through its cellular receptor C5aR1, has pote
Externí odkaz:
https://doaj.org/article/a119f5892a0d43a4859a59ccd6f0ea4d
Autor:
Alecsander F. Bressan, Victoria Oliveira Maia, Beatriz de Souza Rodrigues, Giuliana Bertozi, Sabrina S. Batah, Alexandre T. Fabro, Glória Pelizzo, Ugo Maria Pierucci, Rita C. Tostes, Lourenço Sbragia, Fernando S. Carneiro
Publikováno v:
Pharmacological Research, Vol 191, Iss , Pp 106749- (2023)
Left congenital diaphragmatic hernia (CDH) can lead to pulmonary arteries abnormalities in the contralateral and ipsilateral sides of the diaphragm. Nitric oxide (NO) is the main therapy used to attenuate the vascular effects of CDH, but it is not al
Externí odkaz:
https://doaj.org/article/2a91b1a363a3445a8b8deb63b6042dfe
Autor:
Ana CG Salina, Douglas dos-Santos, Tamara S Rodrigues, Marlon Fortes-Rocha, Edismauro G Freitas-Filho, Daniel L Alzamora-Terrel, Icaro MS Castro, Thais FC Fraga da Silva, Mikhael HF de Lima, Daniele C Nascimento, Camila M Silva, Juliana E Toller-Kawahisa, Amanda Becerra, Samuel Oliveira, Diego B Caetité, Leticia Almeida, Adriene Y Ishimoto, Thais M Lima, Ronaldo B Martins, Flavio Veras, Natália B do Amaral, Marcela C Giannini, Letícia P Bonjorno, Maria IF Lopes, Maira N Benatti, Sabrina S Batah, Rodrigo C Santana, Fernando C Vilar, Maria A Martins, Rodrigo L Assad, Sergio CL de Almeida, Fabiola R de Oliveira, Eurico Arruda Neto, Thiago M Cunha, José C Alves-Filho, Vania LD Bonato, Fernando Q Cunha, Alexandre T Fabro, Helder I Nakaya, Dario S Zamboni, Paulo Louzada-Junior, Rene DR Oliveira, Larissa D Cunha
Publikováno v:
eLife, Vol 11 (2022)
COVID-19 is a disease of dysfunctional immune responses, but the mechanisms triggering immunopathogenesis are not established. The functional plasticity of macrophages allows this cell type to promote pathogen elimination and inflammation or suppress
Externí odkaz:
https://doaj.org/article/90b9106f59824489a18e93537ba61d8e
Autor:
Sabrina S. Batah, Maíra N. Benatti, Li Siyuan, Wagner M. Telini, Jamile O. Barboza, Marcelo B. Menezes, Tales R. Nadai, Keyla S. G. Sá, Chirag M. Vaswani, Sahil Gupta, Dario S. Zamboni, Danilo T. Wada, Rodrigo T. Calado, Renê D. R. Oliveira, Paulo Louzada‐Junior, Maria Auxiliadora‐Martins, Flávio P. Veras, Larissa D. Cunha, Thiago M. Cunha, Rodrigo Luppino‐Assad, Marcelo L. Balancin, Sirlei S. Morais, Ronaldo B. Martins, Eurico Arruda, Fernando Chahud, Marcel Koenigkam Santos, Andrea A. Cetlin, Fernando Q. Cunha, Claudia dos Santos, Vera L. Capelozzi, Junya Fukuoka, Rosane Duarte Achcar, Alexandre T. Fabro
Publikováno v:
Clinical and Translational Medicine, Vol 12, Iss 1, Pp n/a-n/a (2022)
Externí odkaz:
https://doaj.org/article/74cfa39831ad4d07aeb0b2b6fbc99819
Autor:
Bruna M.S. Silva, Giovanni F. Gomes, Flavio P. Veras, Seppe Cambier, Gabriel V.L. Silva, Andreza U. Quadros, Diego B. Caetité, Daniele C. Nascimento, Camila M.S. Silva, Juliana C. Costa Silva, Samara Damasceno, Ayda H. Schneider, Fabio Beretta, Sabrina S. Batah, Icaro M.S. Castro, Isadora M. Paiva, Tamara Rodrigues, Ana Salina, Ronaldo Martins, Guilherme C. Martelossi Cebinelli, Naira L. Bibo, Daniel Macedo de Melo Jorge, Helder I. Nakaya, Dario S. Zamboni, Luiz O. Leiria, Alexandre T. Fabro, José C. Alves-Filho, Eurico Arruda, Paulo Louzada-Junior, Renê D.R. Oliveira, Larissa D. Cunha, Pierre Van Mol, Lore Vanderbeke, Simon Feys, Els Wauters, Laura Brandolini, Andrea Aramini, Fernando Q. Cunha, Jörg Köhl, Marcello Allegretti, Diether Lambrechts, Joost Wauters, Paul Proost, Thiago M. Cunha
Patients with severe COVID-19 develop acute respiratory distress syndrome (ARDS) that may progress to cytokine storm syndrome, organ dysfunction, and death. Considering that complement component 5a (C5a), through its cellular receptor C5aR1, has pote
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::55b1fb8f63bdada259121518f1293a49
https://lirias.kuleuven.be/handle/20.500.12942/719126
https://lirias.kuleuven.be/handle/20.500.12942/719126
Autor:
Sahil Gupta, Hajera Amatullah, James N. Tsoporis, Kuiru Wei, Ana Paula Teixeira Monteiro, Amin M. Ektesabi, Amir K. Varkouhi, Chirag M. Vaswani, Amanda Formosa, Alexandre T. Fabro, Sri Nagarjun Batchu, Chris Fjell, James A. Russell, Keith R. Walley, Andrew Advani, Thomas G. Parker, John C. Marshall, Patricia R. M. Rocco, Gregory D. Fairn, Tak Wah Mak, Claudia C. dos Santos
Publikováno v:
Cell Death & Differentiation. 29:2024-2033
The ability to effectively clear infection is fundamental to host survival. Sepsis, defined as dysregulated host response to infection, is a heterogenous clinical syndrome that does not uniformly clear intact bacterial or sterile infection (i.e., lip
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d0ffe6c7edb91e1827bdc2f23575e12
https://doi.org/10.1038/s41418-022-00993-2
https://doi.org/10.1038/s41418-022-00993-2