Zobrazeno 1 - 10
of 381
pro vyhledávání: '"A T, Urbanus"'
Autor:
Minka Zivkovic, Elisabeth Pols - van Veen, Vossa van der Vegte, Silvie A.E. Sebastian, Annick S. de Moor, Suzanne J.A. Korporaal, Roger E.G. Schutgens, Rolf T. Urbanus, Erik Beckers, Michiel Coppens, Jeroen Eikenboom, Louise Hooimeijer, Gerard Jansen, Roger Schutgens, Rolf Urbanus, Emile van den Akker, Wala Al Arashi, Ryanne Arisz, Lieke Baas, Ruben Bierings, Maartje van den Biggelaar, Johan Boender, Anske van der Bom, Mettine Bos, Martijn Brands, Annelien Bredenoord, Laura Bukkems, Lex Burdorf, Jessica Del Castillo Alferez, Michael Cloesmeijer, Marjon Cnossen, Mariëtte Driessens, Karin Fijnvandraat, Kathelijn Fischer, Geertje Goedhart, Tine Goedhart, Samantha Gouw, Rieke van der Graaf, Masja de Haas, Lotte Haverman, Jan Hazelzet, Shannon van Hoorn, Elise Huisman, Nathalie Jansen, Alexander Janssen, Sean de Jong, Sjoerd Koopman, Marieke Kruip, Sebastiaan Laan, Frank Leebeek, Nikki van Leeuwen, Hester Lingsma, Moniek de Maat, Ron Mathôt, Felix van der Meer, Karina Meijer, Sander Meijer, Stephan Meijer, Iris van Moort, Caroline Mussert, Hans Kristian Ploos van Amstel, Suzanne Polinder, Diaz Prameyllawati, Simone Reitsma, Eliza Roest, Lorenzo Romano, Saskia Schols, Carin Uyl, Jan Voorberg, Huan Zhang
Publikováno v:
Research and Practice in Thrombosis and Haemostasis, Vol 8, Iss 7, Pp 102582- (2024)
Background: Glycoprotein (GP)VI is a platelet-specific collagen receptor required for platelet activation during hemostasis. Platelet reactivity toward collagen is routinely assessed during diagnostic workup of platelet disorders. GPVI can be activat
Externí odkaz:
https://doaj.org/article/0ff9e6640dac449daeff9b624d1422ef
Autor:
Valérie L. B. I. Jansen, Dagmar J. M. van Mourik, Mark Davids, Kika van Bergen en Henegouwen, Tessa Noordermeer, Johannes H. M. Levels, Maarten Limper, Michiel Coppens, Max Nieuwdorp, Rolf T. Urbanus, Saskia Middeldorp, Thijs E. van Mens
Publikováno v:
TH Open, Vol 08, Iss 03, Pp e308-e316 (2024)
Background The origin of autoantibodies in patients with antiphospholipid syndrome (APS) is unknown. The gut microbiome contributes to autoimmunity and contains peptide homologues to the main APS autoantigen, which affect disease activity in animal m
Externí odkaz:
https://doaj.org/article/6f08506fc2544e6586f13a52920f26bd
Autor:
A R T Brand Kanters, N C Roozendaal, N M J Parr, G Pasterkamp, R T Urbanus, S J A Korporaal, Gert J de Borst
Publikováno v:
PLoS ONE, Vol 19, Iss 6, p e0304800 (2024)
BackgroundDespite Antiplatelet therapy (APT), cardiovascular patients undergoing revascularisation remain at high risk for thrombotic events. Individual response to APT varies substantially, resulting in insufficient protection from thrombotic events
Externí odkaz:
https://doaj.org/article/ab6c025d5d3b48ba959723ad87afa67a
Autor:
Marjon H Cnossen, Karin Fijnvandraat, Ron Mathot, Antoine C G Egberts, Rolf T Urbanus, Anouk Donners, Konrad van der Zwet, Ilmar Kruis, Roger Schutgens, Kathelijn Fischer
Publikováno v:
BMJ Open, Vol 13, Iss 6 (2023)
Introduction Emicizumab effectively prevents bleeding in people with haemophilia A (PwHA), but is a burden for national healthcare budgets and consequently may limit access. According to the drug label, dosing of emicizumab is based on body weight wi
Externí odkaz:
https://doaj.org/article/f47c9a04101c40b8914e5a78633418b0
Autor:
Tessa Noordermeer, Roger E. G. Schutgens, Chantal Visser, Emma Rademaker, Moniek P. M. deMaat, A. J. Gerard Jansen, Maarten Limper, Olaf L. Cremer, Marieke J. H. A. Kruip, Henrik Endeman, Coen Maas, Bas deLaat, Rolf T. Urbanus, the Dutch COVID & Thrombosis Coalition (DCTC)
Publikováno v:
Research and Practice in Thrombosis and Haemostasis, Vol 6, Iss 6, Pp n/a-n/a (2022)
Abstract Background Thrombosis is a frequent and severe complication in patients with coronavirus disease 2019 (COVID‐19) admitted to the intensive care unit (ICU). Lupus anticoagulant (LA) is a strong acquired risk factor for thrombosis in various
Externí odkaz:
https://doaj.org/article/d2ccba33e5dc4756adb1c0418654d235
Autor:
Wouter A. van der Heijden, Lisa van de Wijer, Martin Jaeger, Karin Grintjes, Mihai G. Netea, Rolf T. Urbanus, Reinout van Crevel, Lambertus P. van den Heuvel, Maaike Brink, Richard J. Rodenburg, Philip G. de Groot, Andre J. van der Ven, Quirijn de Mast
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
Abstract HIV infection and antiretroviral therapy have been linked to mitochondrial dysfunction. The role of platelet mitochondrial dysfunction in thrombosis, immunoregulation and age-related diseases is increasingly appreciated. Here, we studied pla
Externí odkaz:
https://doaj.org/article/b0bbf380d5ca4357833187a10f35d9b8
Autor:
Anouk A. M. T. Donners, László Gerencsér, Kim C. M. van derElst, Toine C. G. Egberts, Moniek P. M. deMaat, Albert Huisman, Rolf T. Urbanus, Mohsin El Amrani
Publikováno v:
Research and Practice in Thrombosis and Haemostasis, Vol 6, Iss 4, Pp n/a-n/a (2022)
Abstract Background Emicizumab is a new treatment option for people with hemophilia A. Emicizumab was approved with a body‐weight‐based dosage regimen, without laboratory monitoring requirements. Guidelines, however, recommend measuring emicizuma
Externí odkaz:
https://doaj.org/article/2430ded2cc43412e95a67340e7f21f87
Autor:
Farahnaz Waissi, Mirthe Dekker, Ingrid E.M. Bank, Suzanne J.A. Korporaal, Rolf T. Urbanus, Gert J. deBorst, Gerard Pasterkamp, Asbjorn M. Scholtens, Diederick E. Grobbee, Arend Mosterd, Dominique P.V. deKleijn, Leo Timmers
Publikováno v:
Research and Practice in Thrombosis and Haemostasis, Vol 4, Iss 5, Pp 879-885 (2020)
Abstract Background Antiplatelet therapy is the mainstay of secondary prevention of cardiovascular events. Studies suggest that women do not obtain equal therapeutic benefit from antiplatelet therapy compared with men. The link between sex difference
Externí odkaz:
https://doaj.org/article/1264cd3caa6f4c37828931d9b1d5e8d5
Autor:
Maaike W. Blaauwgeers, Marieke J. H. A. Kruip, Erik A. M. Beckers, Michiel Coppens, Jeroen Eikenboom, Karin P. M. vanGalen, Rienk Y. J. Tamminga, Rolf T. Urbanus, Roger E. G. Schutgens, the TiN study group
Publikováno v:
Research and Practice in Thrombosis and Haemostasis, Vol 4, Iss 1, Pp 100-105 (2020)
Abstract Background Patients with congenital blood platelet disorders (CPDs) demonstrate a predominantly mucocutaneous bleeding tendency. Repeated bleeds throughout life can have a significant impact on health status–related quality of life (HR‐Q
Externí odkaz:
https://doaj.org/article/0c9d076f8a854bd88108a3b21255e944
Autor:
Roger E. G. Schutgens, Rolf T. Urbanus
Publikováno v:
Clinical Case Reports, Vol 9, Iss 9, Pp n/a-n/a (2021)
Abstract A patient with Glanzmann Thrombasthenia developed recurrent venous thrombosis with a JAK2 positive myeloproliferative neoplasm. This indicates that the platelet aIIbβIII integrin has no role in venous thrombosis. We discuss the other potent
Externí odkaz:
https://doaj.org/article/6a044820e21d420d89e47991a07dcffd