Zobrazeno 1 - 10
of 66
pro vyhledávání: '"A T, Podany"'
Autor:
Sean N. Avedissian, Johid R. Malik, Anthony T. Podany, Michael Neely, Nathaniel J. Rhodes, Kimberly K. Scarsi, Marc H. Scheetz, Michael J. Duryee, Ukamaka O. Modebelu, Timothy M. Mykris, Lee C. Winchester, Siddappa N. Byrareddy, Courtney V. Fletcher
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-13 (2024)
Abstract Three years after SARS-CoV-2 emerged as a global infectious threat, the virus has become endemic. The neurological complications such as depression, anxiety, and other CNS complications after COVID-19 disease are increasing. The brain, and C
Externí odkaz:
https://doaj.org/article/e66bfd29f1264575848d7e5f72f4345f
Autor:
Johid Reza Malik, Anthony T. Podany, Parvez Khan, Christopher L. Shaffer, Jawed A. Siddiqui, Janina Baranowska‐Kortylewicz, Jennifer Le, Courtney V. Fletcher, Sadia Afruz Ether, Sean N. Avedissian
Publikováno v:
Cancer Medicine, Vol 12, Iss 23, Pp 21075-21096 (2023)
Abstract Background Pediatric brain tumors (PBT) stand as the leading cause of cancer‐related deaths in children. Chemoradiation protocols have improved survival rates, even for non‐resectable tumors. Nonetheless, radiation therapy carries the ri
Externí odkaz:
https://doaj.org/article/f2207ce95fd54c1b9b1d541780c66a2c
Autor:
Suyash Deodhar, Brady Sillman, Aditya N. Bade, Sean N. Avedissian, Anthony T. Podany, JoEllyn M. McMillan, Nagsen Gautam, Brandon Hanson, Bhagya L. Dyavar Shetty, Adam Szlachetka, Morgan Johnston, Michellie Thurman, Daniel J. Munt, Alekha K. Dash, Milica Markovic, Arik Dahan, Yazen Alnouti, Alborz Yazdi, Bhavesh D. Kevadiya, Siddappa N. Byrareddy, Samuel M. Cohen, Benson Edagwa, Howard E. Gendelman
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-15 (2022)
Here, using animal models, Deodhar et al. single parenteral dose of dolutegravir (DTG) prodrug nanocrystals sustains drug protein-adjusted 90% inhibitory concentration for up to a year, without injection site reactions or systemic toxicities.
Externí odkaz:
https://doaj.org/article/0e6c6ddce7834d67b915c46f752da67f
Autor:
Omalla A. Olwenyi, Bannet Asingura, Prossy Naluyima, Godwin Upoki Anywar, Justine Nalunga, Mariam Nakabuye, Michael Semwogerere, Bernard Bagaya, Fatim Cham, Allan Tindikahwa, Francis Kiweewa, Eliezer Z. Lichter, Anthony T. Podany, Courtney V. Fletcher, Siddappa N. Byrareddy, Hannah Kibuuka
Publikováno v:
BMC Complementary Medicine and Therapies, Vol 21, Iss 1, Pp 1-14 (2021)
Abstract Background In Sub-Saharan Africa, herbal therapy continues to be utilized for HIV-1 disease management. However, the therapeutic benefits of these substances remain ambiguous. To date, little is known about the effects of these plant extract
Externí odkaz:
https://doaj.org/article/8ea379121053431ba264e0b48b27eac3
Publikováno v:
Women's Health, Vol 18 (2022)
Introduction: Women account for 23% of new human immunodeficiency virus diagnoses in the United States, yet remain understudied. Adherence to antiretroviral therapy and consequent viral suppression are keys to preventing human immunodeficiency virus
Externí odkaz:
https://doaj.org/article/19e407794d0641ffa7e75e8c09c3ae22
Autor:
Amber K. Virdi, Sang Ho, Melanie S. Seaton, Arnold Z. Olali, Srinivas D. Narasipura, Hannah J. Barbian, Leannie J. Olivares, Hemil Gonzalez, Lee C. Winchester, Anthony T. Podany, Ryan D. Ross, Lena Al-Harthi, Jennillee Wallace
Publikováno v:
Cells, Vol 12, Iss 7, p 1034 (2023)
HIV anti-retrovirals (ARVs) have vastly improved the life expectancy of people living with HIV (PLWH). However, toxic effects attributed to long-term ARV use also contribute to HIV-related co-morbidities such as heart disease, bone loss and HIV-assoc
Externí odkaz:
https://doaj.org/article/a3c846cc78b743889acf18674eee8261
Autor:
Omalla A. Olwenyi, Samuel D. Johnson, Kabita Pandey, Michellie Thurman, Arpan Acharya, Shilpa J. Buch, Howard S. Fox, Anthony T. Podany, Courtney V. Fletcher, Siddappa N. Byrareddy
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Cytotoxic CD4+ T cells (CD4+ CTLs) limit HIV pathogenesis, as evidenced in elite controllers (a subset of individuals who suppress the virus without the need for therapy). CD4+ CTLs have also been shown to kill HIV-infected macrophages. However, litt
Externí odkaz:
https://doaj.org/article/7b1a650c52fb4f668c03c38b40167db0
Autor:
Faithful Makita-Chingombe, Anthony T. Podany, Timothy Mykris, Farai Muzambi, Richard W. Browne, Andrew J. Ocque, Robin DiFrancesco, Lee C. Winchester, Courtney V. Fletcher, Tinashe Mudzviti, Charles C. Maponga, Gene D. Morse
Publikováno v:
African Journal of Laboratory Medicine, Vol 10, Iss 1, Pp e1-e5 (2021)
An international HIV pharmacology specialty laboratory (PSL) was established at the University of Zimbabwe to increase bioanalytical and investigator capacities. Quantitation of plasma nevirapine in samples from the AIDS Clinical Trials Group protoco
Externí odkaz:
https://doaj.org/article/d0b883e9cab249519dfbc264895d90a3
Autor:
Zhen Ye, Mai Mohamed Abdelmoaty, Stephen M. Curran, Shetty Ravi Dyavar, Devendra Kumar, Yazen Alnouti, Don W. Coulter, Anthony T. Podany, Rakesh K. Singh, Joseph A. Vetro
Publikováno v:
Non-Coding RNA, Vol 8, Iss 1, p 8 (2022)
RNA interference (RNAi) molecules have tremendous potential for cancer therapy but are limited by insufficient potency after intravenous (IV) administration. We previously found that polymer complexes (polyplexes) formed between 3′-cholesterol-modi
Externí odkaz:
https://doaj.org/article/3951c0e7bdf9432e8a40f17a3a5abd94
Autor:
Sarah S. Lee, Joshua P. Havens, Harlan R. Sayles, Jennifer L. O’Neill, Anthony T. Podany, Susan Swindells, Kimberly K. Scarsi, Sara H. Bares
Publikováno v:
BMC Infectious Diseases, Vol 18, Iss 1, Pp 1-5 (2018)
Abstract Background Tenofovir alafenamide (TAF) is associated with less renal and bone toxicity compared with tenofovir disoproxil (TDF). TAF's recent FDA approval has spurred HIV providers to consider switching antiretroviral therapy (ART) regimens
Externí odkaz:
https://doaj.org/article/328f974158c9455089f4319437afea2b