Zobrazeno 1 - 10
of 195
pro vyhledávání: '"A T, Kopylov"'
Autor:
Denis V. Petrovskiy, Kirill S. Nikolsky, Liudmila I. Kulikova, Vladimir R. Rudnev, Tatiana V. Butkova, Kristina A. Malsagova, Arthur T. Kopylov, Anna L. Kaysheva
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-15 (2024)
Abstract The primary objective of analyzing the data obtained in a mass spectrometry-based proteomic experiment is peptide and protein identification, or correct assignment of the tandem mass spectrum to one amino acid sequence. Comparison of empiric
Externí odkaz:
https://doaj.org/article/67db65e99f694b26a143ce635b8ee83d
Autor:
Arthur T. Kopylov, Alexander A. Stepanov, Tatiana V. Butkova, Kristina A. Malsagova, Natalia V. Zakharova, Georgy P. Kostyuk, Artem U. Elmuratov, Anna L. Kaysheva
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-20 (2023)
Abstract Despite of multiple systematic studies of schizophrenia based on proteomics, metabolomics, and genome-wide significant loci, reconstruction of underlying mechanism is still a challenging task. Combination of the advanced data for quantitativ
Externí odkaz:
https://doaj.org/article/def4c43b120946c79c3a26b7d8e7386e
Autor:
Kristina A. Malsagova, Arthur T. Kopylov, Alexander A. Stepanov, Liudmila I. Kulikova, Alexander A. Izotov, Ksenia A. Yurku, Evgenii I. Balakin, Vasiliy I. Pustovoyt, Anna L. Kaysheva
Publikováno v:
Sports, Vol 12, Iss 3, p 72 (2024)
Proteomic and metabolomic research enables quantitation of the molecular profile of athletes. Multiomic profiling was conducted using plasma samples collected from 18 male athletes performing aerobic activity (running) at high altitude. Metabolomic p
Externí odkaz:
https://doaj.org/article/8eadb7a7609446028e4fa80480f7029e
Autor:
Kristina A. Malsagova, Arthur T. Kopylov, Vasiliy I. Pustovoyt, Evgenii I. Balakin, Ksenia A. Yurku, Alexander A. Stepanov, Liudmila I. Kulikova, Vladimir R. Rudnev, Anna L. Kaysheva
Publikováno v:
Data, Vol 9, Iss 1, p 15 (2024)
High exercise loading causes intricate and ambiguous proteomic and metabolic changes. This study aims to describe the dataset on protein and metabolite contents in plasma samples collected from highly trained athletes across different sports discipli
Externí odkaz:
https://doaj.org/article/dd83ba4991db4508b66c8ee9115fe1be
Autor:
Denis V. Petrovskiy, Kirill S. Nikolsky, Vladimir R. Rudnev, Liudmila I. Kulikova, Tatiana V. Butkova, Kristina A. Malsagova, Arthur T. Kopylov, Anna L. Kaysheva
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 19, p 14439 (2023)
The development and improvement of methods for comparing and searching for three-dimensional protein structures remain urgent tasks in modern structural biology. To solve this problem, we developed a new tool, SAFoldNet, which allows for searching, a
Externí odkaz:
https://doaj.org/article/bd3ed7fa776440339a7385274daae58f
Autor:
Denis V. Petrovskiy, Kirill S. Nikolsky, Vladimir R. Rudnev, Liudmila I. Kulikova, Tatiana V. Butkova, Kristina A. Malsagova, Arthur T. Kopylov, Anna L. Kaysheva
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 17, p 13431 (2023)
Amino acid substitutions and post-translational modifications (PTMs) play a crucial role in many cellular processes by directly affecting the structural and dynamic features of protein interaction. Despite their importance, the understanding of prote
Externí odkaz:
https://doaj.org/article/1d3770b5f32f480a914d792881cb41ae
Autor:
Dmitry Tikhonov, Liudmila Kulikova, Arthur T. Kopylov, Vladimir Rudnev, Alexander Stepanov, Kristina Malsagova, Alexander Izotov, Dmitry Kulikov, Alexey Zulkarnaev, Dmitry Enikeev, Natalia Potoldykova, Anna L. Kaysheva
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-18 (2021)
Abstract Post-translational processing leads to conformational changes in protein structure that modulate molecular functions and change the signature of metabolic transformations and immune responses. Some post-translational modifications (PTMs), su
Externí odkaz:
https://doaj.org/article/69d55964673c4c3ba2e81ab07faa771f
Autor:
Alexander A. Stepanov, Kristina A. Malsagova, Arthur T. Kopylov, Vladimir R. Rudnev, Dmitry E. Karateev, Evgenia I. Markelova, Elena L. Luchikhina, Elena E. Borisova, Anna L. Kaysheva
Publikováno v:
Life, Vol 13, Iss 2, p 596 (2023)
Reduction in tumor necrosis factor (αTNF) and interleukin-6 (IL-6) activities is a widely utilized strategy for the treatment of rheumatoid arthritis (RA) with a high success rate. Despite both schemes targeting the deprivation of inflammatory react
Externí odkaz:
https://doaj.org/article/fff75522eaf44f27ba73c8c5e7c455cf
Autor:
Kristina A. Malsagova, Arthur T. Kopylov, Alexander A. Stepanov, Dmitry V. Enikeev, Natalia V. Potoldykova, Evgenii I. Balakin, Vasiliy I. Pustovoyt, Anna L. Kaysheva
Publikováno v:
Sports, Vol 11, Iss 2, p 36 (2023)
The aim of this study was to determine the influence of high-intensity training under extreme conditions (T = 40 °C) on the metabolism and immunological reactions of athletes. Male triathletes (n = 11) with a high level of sports training performed
Externí odkaz:
https://doaj.org/article/753ea8fa4191402799d0f09fc9ea6d47
Autor:
Maxim S. Kondratyev, Vladimir R. Rudnev, Kirill S. Nikolsky, Denis V. Petrovsky, Liudmila I. Kulikova, Kristina A. Malsagova, Alexander A. Stepanov, Arthur T. Kopylov, Anna L. Kaysheva
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 24, p 16096 (2022)
Herein, we aimed to highlight current “gaps” in the understanding of the potential interactions between the Anle138b isomer ligand, a promising agent for clinical research, and the intrinsically disordered alpha-synuclein protein. The presence of
Externí odkaz:
https://doaj.org/article/20e71666864a4f6687b2b8d0c253a583