Zobrazeno 1 - 10
of 118
pro vyhledávání: '"A T, Kicman"'
Autor:
Joanna Czerwinska, Mark C. Parkin, Agostino Cilibrizzi, Claire George, Andrew T. Kicman, Paul I. Dargan, Vincenzo Abbate
Publikováno v:
Pharmaceuticals, Vol 14, Iss 1, p 5 (2020)
Mephedrone, which is one of the most popular synthetic cathinones, has one chiral centre and thus exists as two enantiomers: R-(+)-mephedrone and S-(−)-mephedrone. There are some preliminary data suggesting that the enantiomers of mephedrone may di
Externí odkaz:
https://doaj.org/article/a8ab4a54f4b747d6b6ba2232d7b2e83a
Autor:
Vincenzo Abbate, Catia Costa, Min Jang, Andrew T. Kicman, Mark C. Parkin, Joanna Czerwinska, Melanie J. Bailey, Claire George, Paul I. Dargan
Publikováno v:
The Analyst. 145:3038-3048
The use of synthetic stimulants, including designer cathinones, remains a significant concern worldwide. Thus, the detection and identification of synthetic cathinones in biological matrices is of paramount importance for clinical and forensic labora
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19672408d952f81d6e7e1d244e765b7e
https://doi.org/10.1039/c9an02477h
https://doi.org/10.1039/c9an02477h
Autor:
Joanna Czerwinska, Mark C. Parkin, Claire George, Andrew T. Kicman, Paul I. Dargan, Vincenzo Abbate
Publikováno v:
Drug testing and analysis. 14(4)
Mephedrone is a stimulant drug structurally related to cathinone. At present, there are no data available on the excretion profile of mephedrone and its metabolites in urine after controlled intranasal administration to human volunteers. In this stud
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::76ade85895b19f4505fc759e22bd73bf
https://pubmed.ncbi.nlm.nih.gov/34984836
https://pubmed.ncbi.nlm.nih.gov/34984836
Autor:
Claire George, Paul I. Dargan, Agostino Cilibrizzi, Andrew T. Kicman, Vincenzo Abbate, Joanna Czerwinska, Mark C. Parkin
Publikováno v:
Pharmaceuticals, Vol 14, Iss 5, p 5 (2021)
Czerwinska, J, Parkin, M C, Cilibrizzi, A, George, C, Kicman, A T, Dargan, P I & Abbate, V 2020, ' Pharmacokinetics of Mephedrone Enantiomers in Whole Blood after a Controlled Intranasal Administration to Healthy Human Volunteers ', Pharmaceuticals, vol. 14, no. 1, 5 . https://doi.org/10.3390/ph14010005
Pharmaceuticals
Volume 14
Issue 1
Czerwinska, J, Parkin, M C, Cilibrizzi, A, George, C, Kicman, A T, Dargan, P I & Abbate, V 2020, ' Pharmacokinetics of Mephedrone Enantiomers in Whole Blood after a Controlled Intranasal Administration to Healthy Human Volunteers ', Pharmaceuticals, vol. 14, no. 1, 5 . https://doi.org/10.3390/ph14010005
Pharmaceuticals
Volume 14
Issue 1
Mephedrone, which is one of the most popular synthetic cathinones, has one chiral centre and thus exists as two enantiomers: R-(+)-mephedrone and S-(&minus
)-mephedrone. There are some preliminary data suggesting that the enantiomers of mephedro
)-mephedrone. There are some preliminary data suggesting that the enantiomers of mephedro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a61577c3ecadf1a23075b40347c81c80
https://www.mdpi.com/1424-8247/14/1/5
https://www.mdpi.com/1424-8247/14/1/5
Autor:
Vincenzo Abbate, Andrew T. Kicman, Joanna Czerwinska, Paul I. Dargan, Claire George, Mark C. Parkin
Publikováno v:
Journal of analytical toxicology. 45(7)
Mephedrone is a popular synthetic cathinone, known for its psychostimulant effects. At present, there is no data available on the pharmacokinetics of mephedrone and its metabolites in concurrently collected whole blood and plasma samples after a cont
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d0a8f41ad4bd708887e47897ad4481b
https://pubmed.ncbi.nlm.nih.gov/32986113
https://pubmed.ncbi.nlm.nih.gov/32986113
Autor:
Wei-Ru Chen, Po-Hsin Kong, Christoph Sauer, Huei-Wen Chen, Hsiang-Yu Chan, Da-Peng Yang, Yung-Cheng Jair, Hsin-Tung Liu, Tsang-Yaw Lin, Muh-Yong Yen, Yung-Feng Yen, Sheng-Huang Chang, Lan-Hui Li, Claire George, Ya-Chi Chang, Yi-Hsin Wu, Hsiao-Lin Hwa, Chia-Yang Chen, Jung-Hsuan Chen, Andrew T. Kicman, Hans H. Maurer, Pai-Shan Chen
Publikováno v:
Regulatory Toxicology and Pharmacology. 128:105097
In forensic toxicology, a marker of street heroin use is urgent especially in the absence of urinary 6-monoacetylmorphine. ATM4G, the Glucuronide of Acetylated product of Thebaine compound 4 Metabolite (ATM4), arising from byproducts of street heroin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::93a167e7b3176d957454630aef31c0ba
https://doi.org/10.1016/j.yrtph.2021.105097
https://doi.org/10.1016/j.yrtph.2021.105097
Autor:
Eleanor Menzies, David M. Wood, Andrew T. Kicman, John R. H. Archer, Lars Ambach, Mark C. Parkin, Christophe P. Stove, Paul I. Dargan
Publikováno v:
Drug Testing and Analysis. 11:709-720
Cocaine is a common illicit stimulant and is mainly metabolized by hydrolysis to benzoylecgonine (BE) and ecgonine methyl ester (EME), but also to minor metabolites like norcocaine, or hydroxy-BE. When ethanol is present, cocaethylene is formed. Drie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd419cac50090001bcdafc86d54407bb
https://doi.org/10.1002/dta.2537
https://doi.org/10.1002/dta.2537
Autor:
Marjaana Viljanto, Mark C. Parkin, Andrew T. Kicman, Christopher J. Walker, Catarina Horro Pita, James Scarth
Publikováno v:
Drug Testing and Analysis. 10:1469-1473
The effective analysis of anabolic-androgenic steroids in urine usually requires a suitable deconjugation method for the analysis of phase II metabolites such as sulphates and glucuronides. Acid hydrolysis using methanolysis is one adopted method of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::481b8ee667d3cffb09b1dc12c7b5c177
https://doi.org/10.1002/dta.2402
https://doi.org/10.1002/dta.2402
Autor:
Pamela Hincks, Kim Wolff, Simon Biddle, Marjaana Viljanto, Christopher J. Walker, James Scarth, Tessa Muir, Andrew T. Kicman
Publikováno v:
Viljanto, M, Kicman, A T, Walker, C J, Wolff, K, Muir, T, Hincks, P, Biddle, S & Scarth, J 2019, ' Bioformation of boldenone and related precursors/metabolites in equine feces and urine, with relevance to doping control ', Drug Testing And Analysis . https://doi.org/10.1002/dta.2706
Boldenone (1‐dehydrotestosterone) is an exogenous anabolic‐androgenic steroid(AAS) but is also known to be endogenous in the entire male horse and potentiallyformed by microbes in voided urine, the gastrointestinal tract, or feed resulting inits
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d9494bb33f21a0cc8acd40397805bc4
https://kclpure.kcl.ac.uk/en/publications/3ae41773-ca33-4f92-b63b-90eedc8d4ac0
https://kclpure.kcl.ac.uk/en/publications/3ae41773-ca33-4f92-b63b-90eedc8d4ac0
Autor:
Adam Cawley, Craig J. Suann, Pamela Hincks, Mark C. Parkin, Marjaana Viljanto, Lynn Hillyer, James Scarth, Christopher J. Walker, Glenys Noble, Andrew T. Kicman
Publikováno v:
Drug Testing and Analysis. 9:1328-1336
Detection of testosterone and/or its pro-drugs in the gelding is currently regulated by the application of an international threshold for urinary testosterone of 20 ng/mL. The use of steroid ratios may provide a useful supplementary approach to aid i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1a380e618d933f82ca893c5ded4be73a
https://doi.org/10.1002/dta.2109
https://doi.org/10.1002/dta.2109