Joint interaction of ethidium bromide and methylene blue with DNA. The effect of ionic strength on binding thermodynamic parameters

Autor: Armen T. Karapetian, Margarita A. Torosyan, Marine A. Parsadanyan, Ara P. Antonyan, Poghos O. Vardevanyan

Publikováno v: Journal of Biomolecular Structure and Dynamics. 34:1377-1382

Large amount of data of experimental and theoretical studies have shown that ethidium bromide (EtBr) and methylene blue (MB) may bind to nucleic acids via three modes: intercalation between two adjacent base pairs, insertion into the plane between ne

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d607cc58548be1b332132ca845aac5ad
https://doi.org/10.1080/07391102.2015.1079557

The Globular State of the Single-Stranded RNA: Effect of the Secondary Structure Rearrangements

Autor: Armen T. Karapetian, Zareh A. Grigoryan

Publikováno v: Journal of Nucleic Acids, Vol 2015 (2015)
Journal of Nucleic Acids

The mutual influence of the slow rearrangements of secondary structure and fast collapse of the long single-stranded RNA (ssRNA) in approximation of coarse-grained model is studied with analytic calculations. It is assumed that the characteristic tim

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0edd354b3bb9f5c8243de9f1bad2b886
https://doi.org/10.1155/2015/295264

The influence of GC/AT composition on intercalating and semi-intercalating binding of ethidium bromide to DNA

Autor: Ara P. Antonyan, Armen T. Karapetian, Marine A. Parsadanyan, Mariam A. Shahinyan, Poghos O. Vardevanyan, Margarita A. Torosyan, Lilit A. Hambardzumyan

Publikováno v: Journal of the Brazilian Chemical Society v.23 n.11 2012
Journal of the Brazilian Chemical Society
Sociedade Brasileira de Química (SBQ)
instacron:SBQ
Journal of the Brazilian Chemical Society, Volume: 23, Issue: 11, Pages: 2016-2020, Published: 11 DEC 2012

The binding parameters of ethidium bromide (EtBr) with DNA of various GC/AT ratios were determined using absorption and fluorescence spectroscopy. Our experimental data clearly demonstrate the co-existence of fluorescing and non-fluorescing types of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::346bfb9b5de4cb374f3870b73c105c95
https://doi.org/10.1590/s0103-50532012005000076

Theoretical treatment of helix-coil transition of complexes DNA with two different ligands having different binding parameters

Autor: Poghos O. Vardevanyan, Armen T. Karapetian, Mikayel V. Minasyants, Yevgeni Sh. Mamasakhlisov, Zareh A. Grigoryan

Publikováno v: Journal of biomolecular structuredynamics. 34(1)

The melting transition of DNA-ligand complexes, allowing for two binding mechanisms to different DNA conformations is treated theoretically. The obtained results express the behavior of the experimentally measurable quantities, degree of denaturation

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d1aeed3b70002d9d20b4372daf8fc19
https://pubmed.ncbi.nlm.nih.gov/25723721

[Hemodynamic changes in myopia of different degrees]

Autor: V R, Mamikonian, O A, Shmeleva-Demir, S I, Kharlap, D V, Andzhelova, E E, Kazarian, N V, Makashova, N S, Galoian, Iu V, Mazurova, A A, Tatevosian, A T, Karapetian

Publikováno v: Vestnik oftalmologii. 129(6)

A total of 78 patients (143 eyes) with low, medium and high degree myopia were assessed. Apart from standard ophthalmological tests, flowmetry and duplex ultrasound of ocular vessels were performed in all cases to evaluate volumetric and velocity par

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::16828f5b48488d7633e226e8ae1f861d
https://pubmed.ncbi.nlm.nih.gov/24624798