Zobrazeno 1 - 10
of 31
pro vyhledávání: '"A T, Beggah"'
Publikováno v:
Molecular Pain, vol. 5, no. 52, pp. 1-17
Molecular Pain
Molecular Pain, Vol 5, Iss 1, p 52 (2009)
Molecular Pain
Molecular Pain, Vol 5, Iss 1, p 52 (2009)
Background Gene transfer to nociceptive neurons of the dorsal root ganglia (DRG) is a promising approach to dissect mechanisms of pain in rodents and is a potential therapeutic strategy for the treatment of persistent pain disorders such as neuropath
Conditional Mineralocorticoid Receptor Expression in the Heart Leads to Life-Threatening Arrhythmias
Autor:
Marie-Edith Oblin, Anne Royer, Yannis Sainte-Marie, Sophie Demolombe, Claude Delcayre, Antoine Ouvrard-Pascaud, Ahmed T. Beggah, Christelle Soukaseum, Brigitte Escoubet, Glenn I. Fishman, Jean-Pierre Benitah, Pierre Maison-Blanche, Aurelie Nguyen Dinh Cat, Nicolette Farman, Flavien Charpentier, Romain Perrier, Khai Le Quang, Fatima Mechta-Grigoriou, Frederic Jaisser
Publikováno v:
Circulation. 111:3025-3033
Background— Life-threatening cardiac arrhythmia is a major source of mortality worldwide. Besides rare inherited monogenic diseases such as long-QT or Brugada syndromes, which reflect abnormalities in ion fluxes across cardiac ion channels as a fin
Publikováno v:
Revue medicale suisse. 10(432)
Myocardial infarction is one of the most important causes of mortality and its incidence exhibits a significant circadian pattern with a peak of maximum frequency between 10 am and 11 am. Furthermore, myocardial infarction size and related mortality
Autor:
Nathalie Courtois-Coutry, Marcel Blot-Chabaud, Say Viengchareun, Nicolette Farman, Michel Fay, Ahmed T. Beggah, Sabri Djelidi, Françoise Cluzeaud, Jean-Pierre Bonvalet
Publikováno v:
Scopus-Elsevier
The regulation of plasma membrane Na + -K + -ATPases (NKA) expression by aldosterone and arginin vasopressin (AVP) in the cortical collecting duct (CCD) has been examined in a new rat CCD cell line, designated as RCCD 2 . This cell line has maintaine
Publikováno v:
Journal of Biological Chemistry. 274:8217-8223
The alpha-subunits of H,K-ATPase (HKAalpha) and Na,K-ATPase require a beta-subunit for maturation. We investigated the role of the beta-subunit in the membrane insertion and stability of the HKAalpha expressed in Xenopus oocytes. Individual membrane
Autor:
Ahmed T. Beggah, Frederic Jaisser
Publikováno v:
Nephron Experimental Nephrology. 6:438-446
Animal transgenesis has proven to be useful for physiological as well as physiopathological studies. Besides the classical approach based on the random integration of a DNA construct in the mouse genome, gene targeting can be achieved using totipoten
Publikováno v:
The Journal of Cell Biology
Subunit assembly plays an essential role in the maturation of oligomeric proteins. In this study, we have characterized the main structural and functional consequences of the assembly of alpha and beta subunits of Na,K-ATPase. Xenopus oocytes injecte
Autor:
P. Burgener-Kairuz, Pascal Béguin, Frederic Jaisser, A. V. Chibalin, Käthi Geering, Ahmed T. Beggah, Bernard C. Rossier, Susanna Cotecchia, P. M. Mathews
Publikováno v:
Journal of Biological Chemistry. 269:24437-24445
Na,K-ATPase is a potential target for regulatory phosphorylation by protein kinase A and C (PKA and PKC). To identify the phosphorylation sites, we have mutated the alpha 1-subunit of Bufo marinus in a highly conservative PKA and in 20 different PKC
Publikováno v:
Biochemistry. 32:14117-14124
To define the structural basis of oligomerization for the alpha- and beta-subunits of Na,K-ATPase, we have attempted to identify the amino acids in the C-terminus of the beta-subunit that are involved in subunit assembly. We predicted that the last 1
Publikováno v:
European Journal of Pain. 13