Zobrazeno 1 - 10
of 9 717
pro vyhledávání: '"A Sleigh"'
Publikováno v:
BJA Open, Vol 12, Iss , Pp 100358- (2024)
Background: Administration of conventional anaesthetic agents is associated with changes in electroencephalogram (EEG) oscillatory dynamics, including a reduction in the peak alpha frequency. Computational models of neurones can reproduce such phenom
Externí odkaz:
https://doaj.org/article/787ae4398cf9416994e3dc445e710779
Publikováno v:
iScience, Vol 27, Iss 11, Pp 111158- (2024)
Summary: Efficient long-range axonal transport is essential for maintaining neuronal function, and perturbations in this process underlie severe neurological diseases. Nodes of Ranvier (NoR) are short, specialized unmyelinated axonal domains with a u
Externí odkaz:
https://doaj.org/article/1528170810e44ac7b7cf79d7b3ada18a
Autor:
Sleigh, James N.1,2 (AUTHOR), Mattedi, Francesca3 (AUTHOR), Richter, Sandy3 (AUTHOR), Annuario, Emily3 (AUTHOR), Ng, Kristal3 (AUTHOR), Steinmark, I. Emilie4 (AUTHOR), Ivanova, Iveta4 (AUTHOR), Darabán, István L.3 (AUTHOR), Joshi, Parth P.3 (AUTHOR), Rhymes, Elena R.1,2 (AUTHOR), Awale, Shirwa4 (AUTHOR), Yahioglu, Gokhan5 (AUTHOR), Mitchell, Jacqueline C.3 (AUTHOR), Suhling, Klaus4 (AUTHOR), Schiavo, Giampietro1,2 (AUTHOR), Vagnoni, Alessio3,6 (AUTHOR) alessio.vagnoni@kcl.ac.uk
Publikováno v:
Aging Cell. Oct2024, Vol. 23 Issue 10, p1-20. 20p.
Autor:
Sleigh, Duncan, Vermeeren, Mats
Publikováno v:
J. Phys. A: Math. Theor. 55 (2022) 475204
We present a variational theory of integrable differential-difference equations (semi-discrete integrable systems). This is a natural extension of the ideas known by the names "Lagrangian multiforms" and "Pluri-Lagrangian systems", which have previou
Externí odkaz:
http://arxiv.org/abs/2204.13063
We describe a variational framework for non-commuting flows, extending the theories of Lagrangian multiforms and pluri-Lagrangian systems, which have gained prominence in recent years as a variational description of integrable systems in the sense of
Externí odkaz:
http://arxiv.org/abs/2204.09663
Publikováno v:
In BJA Open December 2024 12
Autor:
Tosolini, Andrew P., Abatecola, Federico, Negro, Samuele, Sleigh, James N., Schiavo, Giampietro
Publikováno v:
In iScience 15 November 2024 27(11)
Publikováno v:
Humanities & Social Sciences Communications, Vol 11, Iss 1, Pp 1-10 (2024)
Abstract In the age of Machine Learning Algorithms, Artificial Intelligence and Natural Language Processing, digital technologies have become interwoven in various aspects of society, including in our practices for ethical deliberation and decision-m
Externí odkaz:
https://doaj.org/article/a4a1c5d00101482696eaf548f4790a7f
Autor:
Elena R. Rhymes, Rebecca L. Simkin, Ji Qu, David Villarroel-Campos, Sunaina Surana, Yao Tong, Ryan Shapiro, Robert W. Burgess, Xiang-Lei Yang, Giampietro Schiavo, James N. Sleigh
Publikováno v:
Neurobiology of Disease, Vol 195, Iss , Pp 106501- (2024)
Charcot-Marie-Tooth disease (CMT) is a genetic peripheral neuropathy caused by mutations in many functionally diverse genes. The aminoacyl-tRNA synthetase (ARS) enzymes, which transfer amino acids to partner tRNAs for protein synthesis, represent the
Externí odkaz:
https://doaj.org/article/6a2c5beddc18443097b6a65f58d65c80
We define a conformally invariant action S on gauge connections on a closed pseudo-Riemannian manifold M of dimension 6. At leading order this is quadratic in the gauge connection. The Euler-Lagrange equations of S, with respect to variation of the g
Externí odkaz:
http://arxiv.org/abs/2107.08515