Zobrazeno 1 - 10
of 1 113
pro vyhledávání: '"A Singanayagam"'
Autor:
Orestis Katsoulis, Marie Toussaint, Millie M. Jackson, Patrick Mallia, Joseph Footitt, Kyle T. Mincham, Garance F. M. Meyer, Tata Kebadze, Amy Gilmour, Merete Long, Andrew D. Aswani, Robert J. Snelgrove, Sebastian L. Johnston, James D. Chalmers, Aran Singanayagam
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-14 (2024)
Abstract Respiratory viruses are a major trigger of exacerbations in chronic obstructive pulmonary disease (COPD). Airway neutrophilia is a hallmark feature of stable and exacerbated COPD but roles played by neutrophil extracellular traps (NETS) in d
Externí odkaz:
https://doaj.org/article/451ae3fbca9b4699b68a5ae8f85d6f20
Autor:
Mark Almond, Hugo A. Farne, Millie M. Jackson, Akhilesh Jha, Orestis Katsoulis, Oliver Pitts, Tanushree Tunstall, Eteri Regis, Jake Dunning, Adam J. Byrne, Patrick Mallia, Onn Min Kon, Ken A. Saunders, Karen D. Simpson, Robert J. Snelgrove, Peter J. M. Openshaw, Michael R. Edwards, Wendy S. Barclay, Liam M. Heaney, Sebastian L. Johnston, Aran Singanayagam
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-14 (2023)
Abstract Obesity is a well-recognized risk factor for severe influenza infections but the mechanisms underlying susceptibility are poorly understood. Here, we identify that obese individuals have deficient pulmonary antiviral immune responses in bron
Externí odkaz:
https://doaj.org/article/8d985523dc6242578a25e3fd4216932b
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 11 (2024)
Chronic obstructive pulmonary disease (COPD), particularly following acute exacerbations (AE-COPD), significantly heightens the risks and mortality associated with acute myocardial infarction (AMI). The intersection of COPD and AMI is characterised b
Externí odkaz:
https://doaj.org/article/b17f7e3e15954f309b5fcc23106ca20c
Autor:
Anika Singanayagam, Dimitra Klapsa, Shirelle Burton-Fanning, Julian Hand, Thomas Wilton, Laura Stephens, Ryan Mate, Benjamin Shillitoe, Cristina Celma, Mary Slatter, Terry Flood, Robin Gopal, Javier Martin, Maria Zambon
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-9 (2023)
Abstract Increasing detections of vaccine-derived poliovirus (VDPV) globally, including in countries previously declared polio free, is a public health emergency of international concern. Individuals with primary immunodeficiency (PID) can excrete po
Externí odkaz:
https://doaj.org/article/1e38ffc923f544d9a7f88e28fdf9bec8
Publikováno v:
Livers, Vol 3, Iss 2, Pp 240-257 (2023)
The peritoneum represents a confined microenvironment that has an emerging role as a distinct immunological compartment. In health, this niche is mainly populated by a heterogenous group of macrophages and T lymphocytes but also Natural Killer cells
Externí odkaz:
https://doaj.org/article/3184eda247a34fbfb4dcf8a08e7297f7
Autor:
Ritchie, Andrew I., Singanayagam, Aran, Mitchell, Sebastian, Wedzicha, Jadwiga A., Shah, Anand, Bloom, Chloë I.
Publikováno v:
In Chest October 2023 164(4):875-884
Autor:
Zhou, Jie †, Singanayagam, Anika †, Goonawardane, Niluka, Moshe, Maya, Sweeney, Fiachra P, Sukhova, Ksenia, Killingley, Ben, Kalinova, Mariya, Mann, Alex J, Catchpole, Andrew P, Barer, Michael R, Ferguson, Neil M, Chiu, Christopher, Barclay, Wendy S *
Publikováno v:
In The Lancet Microbe August 2023 4(8):e579-e590
Autor:
Oltin-Tiberiu Pop, Anne Geng, Emilio Flint, Arjuna Singanayagam, Caner Ercan, Lucia Possamai, Vishal C. Patel, Patrizia Kuenzler, Marie-Anne Meier, Savas Soysal, Petr Hruz, Otto Kollmar, Kate C. Tatham, Josie K. Ward, Beat Müllhaupt, Achim Weber, Julia Wendon, Jan Hendrik Niess, Markus Heim, David Semela, Christopher Weston, Charalambos G. Antoniades, Luigi Maria Terracciano, Evangelos Triantafyllou, Robert G. Brenig, Christine Bernsmeier
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 16, Iss 1, Pp 17-37 (2023)
Background & Aims: AXL and MERTK expression on circulating monocytes modulated immune responses in patients with cirrhosis (CD14+HLA-DR+AXL+) and acute-on-chronic liver failure (CD14+MERTK+). AXL expression involved enhanced efferocytosis, sustained
Externí odkaz:
https://doaj.org/article/e232e5d8368941d4a69e17e66c9c9998
Autor:
Sofia Roth, Emilio Flint, Lea Ghataore, Vishal C. Patel, Arjuna Singanayagam, Royce P. Vincent, Evangelos Triantafyllou, Yun Ma, William Bernal, Georg Auzinger, Michael Heneghan, Charalambos Antoniades, Mirjam Christ-Crain, Mark J.W. McPhail, David R. Taylor, Julia Wendon, Christine Bernsmeier
Publikováno v:
Gastro Hep Advances, Vol 2, Iss 1, Pp 72-82 (2023)
Background and Aims: The clinical, prognostic, and therapeutic impact of adrenal insufficiency in acute liver failure (ALF) and acute-on-chronic liver failure (ACLF) remains controversial and exact diagnostic criteria are lacking. We sought to determ
Externí odkaz:
https://doaj.org/article/88eb0ec5b8d1477e8d7ccd3b1994e26e
Autor:
Cutajar, Jessica, Quinn, Valerie, Hammett, Sarah, McDermott, Eimèar, Luca, Constanta, Timcang, Kristel, Samuel, Jada, Bremang, Samuel, Evetts, Samuel, Wang, Lulu, Nevin, Sean, Davies, Megan, Tejpal, Chitra, Essoussi, Mohammed, Ketkar, Anjeli V, Miserocchi, Giulia, Catchpole, Harriet, Badhan, Anjna, Dustan, Simon, Day Weber, Isaac J, Marchesin, Federica, Whitfield, Michael G, Poh, John, Kondratiuk, Alexandra, Derqui, Nieves, Koycheva, Aleksandra *, Zhou, Jie *, Pillay, Timesh D *, Crone, Michael A, Hakki, Seran, Fenn, Joe, Kundu, Rhia, Varro, Robert, Conibear, Emily, Madon, Kieran J, Barnett, Jack L, Houston, Hamish, Singanayagam, Anika, Narean, Janakan S, Tolosa-Wright, Mica R, Mosscrop, Lucy, Rosadas, Carolina, Watber, Patricia, Anderson, Charlotte, Parker, Eleanor, Freemont, Paul S, Ferguson, Neil M, Zambon, Maria, McClure, Myra O, Tedder, Richard, Barclay, Wendy S, Dunning, Jake, Taylor, Graham P, Lalvani, Ajit *
Publikováno v:
In The Lancet Microbe June 2023 4(6):e397-e408