Zobrazeno 1 - 10
of 542
pro vyhledávání: '"A Serrano Pozo"'
Autor:
Rosemary J. Jackson, Alexandra Melloni, Dustin P. Fykstra, Alberto Serrano-Pozo, Leslie Shinobu, Bradley T. Hyman
Publikováno v:
Acta Neuropathologica Communications, Vol 12, Iss 1, Pp 1-11 (2024)
Abstract Progressive supranuclear palsy (PSP) is a neurodegenerative disease characterized by 4R tau deposition in neurons as well as in astrocytes and oligodendrocytes. While astrocytic tau deposits are rarely observed in normal aging (so-called agi
Externí odkaz:
https://doaj.org/article/7ddead6245bf458baa493a99e4bcebbf
Autor:
Leonardo D. Garma, Lisbeth Harder, Juan M. Barba-Reyes, Sergio Marco Salas, Mónica Díez-Salguero, Mats Nilsson, Alberto Serrano-Pozo, Bradley T. Hyman, Ana B. Muñoz-Manchado
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-19 (2024)
Abstract Deciphering the striatal interneuron diversity is key to understanding the basal ganglia circuit and to untangling the complex neurological and psychiatric diseases affecting this brain structure. We performed snRNA-seq and spatial transcrip
Externí odkaz:
https://doaj.org/article/728e375820ee48959c617e3c85e173d2
Autor:
Tyagi, Tanish, Magdamo, Colin G., Noori, Ayush, Li, Zhaozhi, Liu, Xiao, Deodhar, Mayuresh, Hong, Zhuoqiao, Ge, Wendong, Ye, Elissa M., Sheu, Yi-han, Alabsi, Haitham, Brenner, Laura, Robbins, Gregory K., Zafar, Sahar, Benson, Nicole, Moura, Lidia, Hsu, John, Serrano-Pozo, Alberto, Prokopenko, Dimitry, Tanzi, Rudolph E., Hyman, Bradley T., Blacker, Deborah, Mukerji, Shibani S., Westover, M. Brandon, Das, Sudeshna
Dementia related cognitive impairment (CI) is a neurodegenerative disorder, affecting over 55 million people worldwide and growing rapidly at the rate of one new case every 3 seconds. 75% cases go undiagnosed globally with up to 90% in low-and-middle
Externí odkaz:
http://arxiv.org/abs/2202.00478
Autor:
Tyagi, Tanish, Magdamo, Colin G., Noori, Ayush, Li, Zhaozhi, Liu, Xiao, Deodhar, Mayuresh, Hong, Zhuoqiao, Ge, Wendong, Ye, Elissa M., Sheu, Yi-han, Alabsi, Haitham, Brenner, Laura, Robbins, Gregory K., Zafar, Sahar, Benson, Nicole, Moura, Lidia, Hsu, John, Serrano-Pozo, Alberto, Prokopenko, Dimitry, Tanzi, Rudolph E., Hyman, Bradley T., Blacker, Deborah, Mukerji, Shibani S., Westover, M. Brandon, Das, Sudeshna
Dementia is a neurodegenerative disorder that causes cognitive decline and affects more than 50 million people worldwide. Dementia is under-diagnosed by healthcare professionals - only one in four people who suffer from dementia are diagnosed. Even w
Externí odkaz:
http://arxiv.org/abs/2111.09115
Autor:
Maria Calvo-Rodriguez, Elizabeth K. Kharitonova, Austin C. Snyder, Steven S. Hou, Maria Virtudes Sanchez-Mico, Sudeshna Das, Zhanyun Fan, Hamid Shirani, K. Peter R. Nilsson, Alberto Serrano-Pozo, Brian J. Bacskai
Publikováno v:
Molecular Neurodegeneration, Vol 19, Iss 1, Pp 1-18 (2024)
Abstract Background Reactive oxidative stress is a critical player in the amyloid beta (Aβ) toxicity that contributes to neurodegeneration in Alzheimer’s disease (AD). Damaged mitochondria are one of the main sources of reactive oxygen species and
Externí odkaz:
https://doaj.org/article/831a14a43be94b0caad5a381475bab71
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Autor:
Ana Muñoz Manchado, Leonardo Garma, Lisbeth Harder, Juan Manuel Barba Reyes, Mónica Díez Salguero, Alberto Serrano Pozo, Bradley Hyman
Publikováno v:
IBRO Neuroscience Reports, Vol 15, Iss , Pp S241-S242 (2023)
Externí odkaz:
https://doaj.org/article/787fb26cd41a4de3a760afeb3c31cf1d
Autor:
Juan Manuel Barba Reyes, Lisbeth Harder, Mónica Díez Salguero, Leonardo Garma, Alberto Serrano Pozo, Bradley Hyman, Ana Muñoz Manchado
Publikováno v:
IBRO Neuroscience Reports, Vol 15, Iss , Pp S367- (2023)
Externí odkaz:
https://doaj.org/article/c523f4a7fb27431aaf44c6c8bd8c5cb9
Autor:
Clara Muñoz-Castro, Ayush Noori, Colin G. Magdamo, Zhaozhi Li, Jordan D. Marks, Matthew P. Frosch, Sudeshna Das, Bradley T. Hyman, Alberto Serrano-Pozo
Publikováno v:
Journal of Neuroinflammation, Vol 19, Iss 1, Pp 1-20 (2022)
Abstract Background Astrocytes and microglia react to Aβ plaques, neurofibrillary tangles, and neurodegeneration in the Alzheimer’s disease (AD) brain. Single-nuclei and single-cell RNA-seq have revealed multiple states or subpopulations of these
Externí odkaz:
https://doaj.org/article/0058df1039144d51a4e84f5e8c7c26e6