Diagnostic and prognostic value of the left atrial myopathy evaluation in cardiac amyloidosis using echocardiography

Autor: Aaisha Ferkh, Paul Geenty, Luke Stefani, Peter Emerson, Jennifer Pham, Karen Byth, Anita C. Boyd, David Richards, Mark S. Taylor, Fiona Kwok, Eddy Kizana, Liza Thomas

Publikováno v: ESC Heart Failure, Vol 11, Iss 6, Pp 4139-4147 (2024)

Abstract Background Cardiac amyloidosis (CA) is an under‐recognized cause of heart failure. Left atrial (LA) myopathy contributes to a worse prognosis in heart failure and is a feature of transthyretin (ATTR) and light‐chain (AL) CA. LA mechanica

Externí odkaz: https://doaj.org/article/a1691475951a478f9498ebe0d1b7e6b7

Integrating the multiple perspectives of people and nature in place-based marine spatial planning

Autor: L. M. Wedding, S. J. Pittman, C. A. Lepczyk, C. Parrain, N. Puniwai, J. S. Boyle, E. G. Goldberg, M. Young, P. Marty, K. Wilhelm, S. Taylor, L. B. Crowder

Publikováno v: npj Ocean Sustainability, Vol 3, Iss 1, Pp 1-15 (2024)

Abstract Marine spatial planning (MSP) has emerged as a tool to enable marine ecosystem-based management that seeks to balance human demands for ocean space with environmental protection. However, there is a history of thinking about our ocean system

Externí odkaz: https://doaj.org/article/03254c95a83a4ce49a846314d94d25f4

Role of the αC-β4 loop in protein kinase structure and dynamics

Autor: Jian Wu, Nisha A Jonniya, Sophia P Hirakis, Cristina Olivieri, Gianluigi Veglia, Alexandr P Kornev, Susan S Taylor

Publikováno v: eLife, Vol 12 (2024)

Although the αC-β4 loop is a stable feature of all protein kinases, the importance of this motif as a conserved element of secondary structure, as well as its links to the hydrophobic architecture of the kinase core, has been underappreciated. We f

Externí odkaz: https://doaj.org/article/d95e3a9288ba4ee1888840bfdd411ffc

Validation of a holistic composite outcome measure for the evaluation of chronic pain interventions

Autor: Rod S. Taylor, Quinton Neville, Christopher M. Mullin, Nagy A. Mekhail, Jan W. Kallewaard, Salim Hayek, Jason E. Pope, Corey W. Hunter, Shrif J. Costandi, Leonardo Kapural, Christopher A. Gilmore, Erika A. Petersen, Kiran V. Patel, Sam Eldabe, Robert M. Levy, Christopher Gilligan, Shravani Durbhakula, Alaa Abd-Elsayed, Marshall Bedder, Patrick Buchanan, Erin Hanson, Angela Leitner, Nicole Soliday, Rui V. Duarte, Daniel J. Clauw, Turo J. Nurmikko

Publikováno v: PAIN Reports, Vol 9, Iss 6, p e1202 (2024)

Abstract. Introduction:. Chronic pain is a personal experience influenced by multiple biopsychosocial factors. Using a pain intensity measure alone to assess the effectiveness of a chronic pain intervention fails to fully evaluate its impact on the m

Externí odkaz: https://doaj.org/article/6e98a81050a341cc86e9ff89e0f5b0e1

Challenge of cardiovascular prevention in primary care: achievement of lifestyle, blood pressure, lipids and diabetes targets for primary prevention in England – results from ASPIRE-3-PREVENT cross-sectional survey

Autor: A Brown, Richard Hobbs, S Jones, J Davies, S Taylor, D Wood, J Cook, T Mason, J Clarke, C Brown, N Ghuman, R Fox, C Jones, S Uddin, J Wilson, C Bell, H Wilson, David Wood, Kornelia Kotseva, Agnieszka Adamska, A Adamska, S Adamska, C Jennings, K Kotseva, P Atkin, C Thomas, A Oliver, C Cox, A Dunne, D Kelly, M Stone, K Beck, J Taylor, S Hunt, J Ryan, P Griffiths, D Shukla, S Richardson, P Steadman, V Glover, N Coote, D Corbett, C Gibbon, F Doyle, L Owen, C Thornley, S Dean, S McKee, N Chauhan, J Howell, R Coles, R Hobbs, K Duff, M Arthur, Catriona Jennings, D Lonsdale, L Steel, T Holt, L Rosenberg, S Cartwright, J Rooney, N Qamar, S Shillito, M Zerominska, U Khan O Hussein, A Ballintine, A Isaew, S Spannuth, J Timmins, F Spannuth, A Agasou, L Andrew, R Hibbell, S Hollishead, S Mazilu-Wood, M Oakley, J Simm, T Nyguyen, C Talbot, R Crowe, K Hollier, T Hembrough, R Symonds, D Diprose, J Beecham, S Bosel-Doyle, L S Taylor, K Priddis, C Winch, S Wytrykowski, Dr L Jones, E Ogburn, N Wooding, S Maslen, C Naylo, R Horsley, H Nobeebaccus, E Tomlinson, L Chaytor, S Garnham, Z Martin, S Mononga, S Steed, S Galbraith-Gibbons, T Sevenoaks

Publikováno v: Open Heart, Vol 11, Iss 2 (2024)

Background Implementation of the cardiovascular disease (CVD) prevention guidelines in the UK has been repeatedly evaluated under the auspices of the British Cardiovascular Society in three Action on Secondary and Primary Prevention by Intervention t

Externí odkaz: https://doaj.org/article/6b748f79da934306af127a3405272dde