Zobrazeno 1 - 10
of 563
pro vyhledávání: '"A S Tawfik"'
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-17 (2024)
Abstract Two new series of oxadiazole and pyrazoline derivatives were designed and synthesized as promising EGFR-TK inhibitors. The in vitro antiproliferative activity was studied against three human cancer cell lines; HCT116, HepG-2 and MCF7 using M
Externí odkaz:
https://doaj.org/article/6284f0a0aa3541e7984ea263ae2507cf
Publikováno v:
IEEE Access, Vol 12, Pp 101484-101496 (2024)
Caching plays an important role in reducing latency and increasing the overall performance of fog computing systems. With the rise of the Internet of Things (IoT) and edge computing, fog computing has become an essential paradigm for addressing the c
Externí odkaz:
https://doaj.org/article/c9cf4173ff284211a3f8a8332d6806bb
Autor:
Rebecca L. McCarthy, Soha S. Tawfik, Ioannis Theocharopoulos, Ravinder Atkar, Bryan McDonald, Sasha Dhoat, Aaron Hughes, Bjorn R. Thomas, Edel A. O’Toole
Publikováno v:
Skin Health and Disease, Vol 4, Iss 3, Pp n/a-n/a (2024)
Abstract Background Atopic eczema is a common, chronic, inflammatory skin condition with considerable heterogeneity. South Asian people living in the UK frequently have low serum vitamin D3 (25(OH)D3), and those with atopic disease can present with s
Externí odkaz:
https://doaj.org/article/bbd84909b8044484bff134894e043519
Autor:
Esraa A. A. Sultan, Mohamed S. Tawfik
Publikováno v:
GM Crops & Food, Vol 14, Iss 1, Pp 1-11 (2023)
ABSTRACTSesame (Sesamum indicum L.) is an important oil crop and one of the oldest-known oil crops to humankind. Sesame has excellent nutritional and therapeutic properties; it is rich in important fatty acids, protein, fiber, and vital minerals. Oil
Externí odkaz:
https://doaj.org/article/ba2d3bdc557743eaa6e0d1eeffc3e66c
Publikováno v:
Future Internet, Vol 16, Iss 7, p 242 (2024)
Crying is a newborn’s main way of communicating. Despite their apparent similarity, newborn cries are physically generated and have distinct characteristics. Experienced medical professionals, nurses, and parents are able to recognize these variati
Externí odkaz:
https://doaj.org/article/f3f600fd6b19421b9ed1854948ba8572
Autor:
Wafaa A. Ewes, Samar S. Tawfik, Aya M. Almatary, Mashooq Ahmad Bhat, Hamed W. El-Shafey, Ahmed A. B. Mohamed, Abdullah Haikal, Mohammed A. El-Magd, Abdullah A. Elgazar, Marwa Balaha, Abdelrahman Hamdi
Publikováno v:
Molecules, Vol 29, Iss 13, p 3186 (2024)
Cancer remains a leading cause of death worldwide, often resulting from uncontrolled growth in various organs. Protein kinase inhibitors represent an important class of targeted cancer therapies. Recently, the kinases BRAF and VEGFR-2 have shown syne
Externí odkaz:
https://doaj.org/article/a4915b3b03014f48954ca3fc6a3d2663
Autor:
Mohammad M. Al-Sanea, Abdelrahman Hamdi, Ahmed A. B. Mohamed, Hamed W. El-Shafey, Mahmoud Moustafa, Abdullah A. Elgazar, Wagdy M. Eldehna, Hidayat Ur Rahman, Della G. T. Parambi, Rehab M. Elbargisy, Samy Selim, Syed Nasir Abbas Bukhari, Omnia Magdy Hendawy, Samar S. Tawfik
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 38, Iss 1 (2023)
A new series of 2-aminobenzothiazole hybrids linked to thiazolidine-2,4-dione 4a–e, 1,3,4-thiadiazole aryl urea 6a–d, and cyanothiouracil moieties 8a–d was synthesised. The in vitro antitumor effect of the new hybrids was assessed against three
Externí odkaz:
https://doaj.org/article/33b1c246c9694ebf90ed1bf2f5e360ba
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 38, Iss 1 (2023)
Multi-target inhibitors represent useful anticancer agents with superior therapeutic attributes. Here in, two novel series of benzimidazole-triazole hybrids were designed, synthesised as multi-target EGFR, VEGFR-2 and Topo II inhibitors, and evaluate
Externí odkaz:
https://doaj.org/article/19091a4a39dc48c488a42b98d4cbbb79
Autor:
Mohammad M. Al-Sanea, Abdelrahman Hamdi, Simone Brogi, Samar S. Tawfik, Dina I. A. Othman, Mahmoud Elshal, Hidayat Ur Rahman, Della G. T. Parambi, Rehab M. Elbargisy, Samy Selim, Ehab M. Mostafa, Ahmed A. B. Mohamed
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 38, Iss 1 (2023)
A novel series of 12 antipyrine derivatives containing 1,3,4-oxadiazoles (4a-d), 1,3,4-thiadiazoles (6a-d), and pyrimidines (8a-d), was preparedand assessed for its potential in vitro COX-2 inhibitors. Compared to Celecoxib, compounds 4b-d and 8d wer
Externí odkaz:
https://doaj.org/article/81d6be4508e84755a23af8c5f039439b
Publikováno v:
Journal of Radiation Research and Applied Sciences, Vol 15, Iss 3, Pp 91-95 (2022)
Background: Rheumatoid arthritis (RA) remains a long-standing inflammatory syndrome where the joint synovial membrane is inflamed, with subsequent joint deformation. Osteoarthritis (OA) is considered to be a progressive destruction of articular carti
Externí odkaz:
https://doaj.org/article/d54727ecc5544bc3809aa3765b72f57f