Zobrazeno 1 - 10
of 13
pro vyhledávání: '"A S Md Mukarram, Hossain"'
Autor:
Robert E. Hynds, Ariana Huebner, David R. Pearce, Mark S. Hill, Ayse U. Akarca, David A. Moore, Sophia Ward, Kate H. C. Gowers, Takahiro Karasaki, Maise Al Bakir, Gareth A. Wilson, Oriol Pich, Carlos Martínez-Ruiz, A. S. Md Mukarram Hossain, Simon P. Pearce, Monica Sivakumar, Assma Ben Aissa, Eva Grönroos, Deepak Chandrasekharan, Krishna K. Kolluri, Rebecca Towns, Kaiwen Wang, Daniel E. Cook, Leticia Bosshard-Carter, Cristina Naceur-Lombardelli, Andrew J. Rowan, Selvaraju Veeriah, Kevin Litchfield, Philip A. J. Crosbie, Caroline Dive, Sergio A. Quezada, Sam M. Janes, Mariam Jamal-Hanjani, Teresa Marafioti, TRACERx consortium, Nicholas McGranahan, Charles Swanton
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-21 (2024)
Abstract Patient-derived xenograft (PDX) models are widely used in cancer research. To investigate the genomic fidelity of non-small cell lung cancer PDX models, we established 48 PDX models from 22 patients enrolled in the TRACERx study. Multi-regio
Externí odkaz:
https://doaj.org/article/15a9cb6171ca46d4a07fbfbe6bf74b76
Autor:
Alicia-Marie Conway, Simon P. Pearce, Alexandra Clipson, Steven M. Hill, Francesca Chemi, Dan Slane-Tan, Saba Ferdous, A. S. Md Mukarram Hossain, Katarzyna Kamieniecka, Daniel J. White, Claire Mitchell, Alastair Kerr, Matthew G. Krebs, Gerard Brady, Caroline Dive, Natalie Cook, Dominic G. Rothwell
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-12 (2024)
Abstract Cancers of Unknown Primary (CUP) remains a diagnostic and therapeutic challenge due to biological heterogeneity and poor responses to standard chemotherapy. Predicting tissue-of-origin (TOO) molecularly could help refine this diagnosis, with
Externí odkaz:
https://doaj.org/article/d4bcd616a1c54d2c97e8ef0bccad3ec9
Autor:
Maximilian W. Schenk, Sam Humphrey, A. S. Md Mukarram Hossain, Mitchell Revill, Sarah Pearsall, Alice Lallo, Stewart Brown, Samuel Bratt, Melanie Galvin, Tine Descamps, Cong Zhou, Simon P. Pearce, Lynsey Priest, Michelle Greenhalgh, Anshuman Chaturvedi, Alastair Kerr, Fiona Blackhall, Caroline Dive, Kristopher K. Frese
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
The emergence of acquired resistance to standard platinum-etoposide chemotherapy in small cell lung cancer (SCLC) is a common event. Here, the authors using paired pre-treatment and post-chemotherapy circulating tumour cell patient-derived explant (C
Externí odkaz:
https://doaj.org/article/a99beedee95f4504bd782063edbc7711
Autor:
Gemma G. R. Murray, Andrew J. Balmer, Josephine Herbert, Nazreen F. Hadjirin, Caroline L. Kemp, Marta Matuszewska, Sebastian Bruchmann, A. S. Md. Mukarram Hossain, Marcelo Gottschalk, Alexander W. Tucker, Eric Miller, Lucy A. Weinert
Publikováno v:
PLoS Genetics, Vol 17, Iss 11 (2021)
Mutation rates vary both within and between bacterial species, and understanding what drives this variation is essential for understanding the evolutionary dynamics of bacterial populations. In this study, we investigate two factors that are predicte
Externí odkaz:
https://doaj.org/article/c33dbcb5f57e4a9bb55867d0f062883d
Autor:
Gemma G. R. Murray, A. S. Md. Mukarram Hossain, Eric Miller, Sebastian Bruchman, Andrew J. Balmer, Marta Matuszewska, Josephine Herbert, Nazreen F. Hadjirin, Robert Mugabi, Ganwu Li, Maria Laura Ferrando, Isabela Maria Fernandes de Oliveira, Thanh Nguyen, Phung L. K. Yen, Aung Zaw Moe, Thiri Su Wai, Marcelo Gottschalk, Virginia Aragon, Peter Valentin-Weigand, Peter M. H. Heegaard, Manouk Vrieling, Min Thein Maw, Hnin Thidar Myint, Ye Tun Win, Ngo Thi Hoa, Steven D. Bentley, Maria J. Clavijo, Jerry M. Wells, Alexander W. Tucker, Lucy A. Weinert
The expansion and intensification of livestock production is predicted to promote the emergence of pathogens. As pathogens sometimes jump between species this can affect the health of humans as well as livestock. Here we investigate how livestock mic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b41872a7c28eb91627966b3cad8db81b
https://doi.org/10.1101/2023.05.17.540811
https://doi.org/10.1101/2023.05.17.540811
Autor:
Matthew Roberts, Julia Ogden, A S Md Mukarram Hossain, Alastair Kerr, Caroline Dive, Jennifer E Beane, Carlos Lopez-Garcia
Lung squamous cell carcinoma (LUSC) is a type of lung cancer with a dismal prognosis that lacks adequate therapies and actionable targets. This disease is characterized by a sequence of low and high-grade preinvasive stages with increasing probabilit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e0c7cd9710f80990357015d390c4bb82
https://doi.org/10.1101/2022.05.06.490640
https://doi.org/10.1101/2022.05.06.490640
Autor:
Josephine Herbert, A. S. Md. Mukarram Hossain, Gemma G. R. Murray, Marta Matuszewska, Lucy A. Weinert, Alexander W. Tucker, Andrew J. Balmer, Marcelo Gottschalk, Sebastian Bruchmann, Nazreen F. Hadjirin, Caroline L. Kemp, Eric L. Miller
Publikováno v:
PLoS Genetics, Vol 17, Iss 11 (2021)
PLoS Genetics, Vol 17, Iss 11, p e1009864 (2021)
PLoS Genetics
PLoS Genetics, Vol 17, Iss 11, p e1009864 (2021)
PLoS Genetics
Funder: Isaac Newton Trust; funder-id: http://dx.doi.org/10.13039/501100004815
Funder: Newnham College, University of Cambridge; funder-id: http://dx.doi.org/10.13039/501100000663
Funder: Biotechnology and Biological Sciences Research Counc
Funder: Newnham College, University of Cambridge; funder-id: http://dx.doi.org/10.13039/501100000663
Funder: Biotechnology and Biological Sciences Research Counc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d228608e857a95997fee11899638f74
https://www.repository.cam.ac.uk/handle/1810/330904
https://www.repository.cam.ac.uk/handle/1810/330904
Autor:
Andrew J. Balmer, Nazreen F. Hadijirin, Marta Matuszewska, Josephine Herbert, A. S. Md. Mukarram Hossain, Gemma G. R. Murray, Alexander W. Tucker, Caroline L. Kemp, Marcelo Gottschalk, Eric L. Miller, Sebastian Bruchmann, Lucy A. Weinert
While mutation is often deleterious, it can also be adaptive. Mutation rates vary both within and between bacterial species, and understanding what drives this variation is essential for understanding the evolutionary dynamics of bacterial population
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1a01fafc2c47ca9fb1ec8e653881117d
https://doi.org/10.1101/2021.04.12.439332
https://doi.org/10.1101/2021.04.12.439332
Autor:
Timothy R. Sterling, Sten H. Vermund, Erik M. Volz, A. S. Md. Mukarram Hossain, Peter F Rebeiro, Art F. Y. Poon, Ann M Dennis, A S Md Simon D W Frost, Marcia L. Kalish
Publikováno v:
AIDS Research and Human Retroviruses
More persons living with HIV reside in the Southern United States than in any other region, yet little is known about HIV molecular epidemiology in the South. We used cluster and phylodynamic analyses to evaluate HIV transmission patterns in middle T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a01a874b37c08f2a19e4e6f01eb45e07
https://www.repository.cam.ac.uk/handle/1810/293409
https://www.repository.cam.ac.uk/handle/1810/293409
Autor:
Oliver, Ratmann, Emma B, Hodcroft, Michael, Pickles, Anne, Cori, Matthew, Hall, Samantha, Lycett, Caroline, Colijn, Bethany, Dearlove, Xavier, Didelot, Simon, Frost, A S Md Mukarram, Hossain, Jeffrey B, Joy, Michelle, Kendall, Denise, Kühnert, Gabriel E, Leventhal, Richard, Liang, Giacomo, Plazzotta, Art F Y, Poon, David A, Rasmussen, Tanja, Stadler, Erik, Volz, Caroline, Weis, Andrew J, Leigh Brown, Christophe, Fraser
Publikováno v:
Molecular Biology and Evolution, 34 (1)
Molecular Biology and Evolution
Molecular Biology and Evolution
Viral phylogenetic methods contribute to understanding how HIV spreads in populations, and thereby help guide the design of prevention interventions. So far, most analyses have been applied to well-sampled concentrated HIV-1 epidemics in wealthy coun
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::174e7b598100adc52ba9e99fd990c70d
http://hdl.handle.net/10044/1/42696
http://hdl.handle.net/10044/1/42696