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Akademický článek

Pilot study for the development of an automatically generated and wearable-based early warning system for the detection of deterioration of hospitalized patients of an acute care hospital

Autor: J.J. Reichl, M. Leifke, S. Wehrli, D. Kunz, L. Geissmann, S. Broisch, M. Illien, D. Wellauer, N. von Dach, S. Diener, V. Manser, V. Herren, A. Angerer, S. Hirsch, B. Hölz, J. Eckstein

Publikováno v: Archives of Public Health, Vol 82, Iss 1, Pp 1-12 (2024)

Abstract Background Acute deteriorations of health status are common in hospitalized patients and are often preceded by changes in their vital signs. Events such as heart attacks, death or admission to the intensive care unit can be averted by early

Externí odkaz: https://doaj.org/article/4bcb58c0ee1d4b66864e5e5eeb1b667d

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Akademický článek

Aberrant zonal recycling of germinal center B cells impairs appropriate selection in lupus

Autor: Gina M. Sanchez, Eden S. Hirsch, Arthur VanValkenburg, Daniel P. Mayer, Komi Gbedande, Rebecca L. Francis, Wenzhi Song, Olivia Q. Antao, Kyleigh E. Brimmer, Alexander Lemenze, Robin Stephens, W. Evan Johnson, Jason S. Weinstein

Publikováno v: Cell Reports, Vol 43, Iss 11, Pp 114978- (2024)

Summary: Autoimmune diseases such as lupus are characterized by polyclonal B cell activation, leading to the production of autoantibodies. The mechanism leading to B cell dysregulation is unclear; however, the defect may lie in selection within germi

Externí odkaz: https://doaj.org/article/30bb3b5827a947bab76bf3fee59c4406

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