Zobrazeno 1 - 10
of 223
pro vyhledávání: '"A S Edison"'
Autor:
Amanda O. Shaver, Brianna M. Garcia, Goncalo J. Gouveia, Alison M. Morse, Zihao Liu, Carter K. Asef, Ricardo M. Borges, Franklin E. Leach, Erik C. Andersen, I. Jonathan Amster, Facundo M. Fernández, Arthur S. Edison, Lauren M. McIntyre
Publikováno v:
Frontiers in Molecular Biosciences, Vol 9 (2022)
Untargeted metabolomics studies are unbiased but identifying the same feature across studies is complicated by environmental variation, batch effects, and instrument variability. Ideally, several studies that assay the same set of metabolic features
Externí odkaz:
https://doaj.org/article/9d83b8419e124151806b3aaea729b8cd
Autor:
Valerie Y. Odeh‐Couvertier, Nathan J. Dwarshuis, Maxwell B. Colonna, Bruce L. Levine, Arthur S. Edison, Theresa Kotanchek, Krishnendu Roy, Wandaliz Torres‐Garcia
Publikováno v:
Bioengineering & Translational Medicine, Vol 7, Iss 2, Pp n/a-n/a (2022)
Abstract Large‐scale, reproducible manufacturing of therapeutic cells with consistently high quality is vital for translation to clinically effective and widely accessible cell therapies. However, the biological and logistical complexity of manufac
Externí odkaz:
https://doaj.org/article/5bc5f7736edf445dad237c85b52c5a43
Publikováno v:
PLoS ONE, Vol 17, Iss 5, p e0268394 (2022)
System biology relies on holistic biomolecule measurements, and untangling biochemical networks requires time-series metabolomics profiling. With current metabolomic approaches, time-series measurements can be taken for hundreds of metabolic features
Externí odkaz:
https://doaj.org/article/d8a8472653ec4c1ebd8e0ac70576a0ed
Autor:
Stéphane L. Benoit, Alan A. Schmalstig, John Glushka, Susan E. Maier, Arthur S. Edison, Robert J. Maier
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-10 (2019)
Abstract The nickel (Ni)-specific chelator dimethylglyoxime (DMG) has been used for many years to detect, quantitate or decrease Ni levels in various environments. Addition of DMG at millimolar levels has a bacteriostatic effect on some enteric patho
Externí odkaz:
https://doaj.org/article/ba948ee605c447938767fdd68a6d105c
Autor:
Meghan Logun, Maxwell B. Colonna, Katherine P. Mueller, Divya Ventarapragada, Riley Rodier, Chaitanya Tondepu, Nicole J. Piscopo, Amritava Das, Stacie Chvatal, Heather B. Hayes, Christian M. Capitini, Daniel J. Brat, Theresa Kotanchek, Arthur S. Edison, Krishanu Saha, Lohitash Karumbaiah
Publikováno v:
Cytotherapy. 25:670-682
Autor:
David S. Wishart, Leo L. Cheng, Valérie Copié, Arthur S. Edison, Hamid R. Eghbalnia, Jeffrey C. Hoch, Goncalo J. Gouveia, Wimal Pathmasiri, Robert Powers, Tracey B. Schock, Lloyd W. Sumner, Mario Uchimiya
Publikováno v:
Metabolites, Vol 12, Iss 8, p 678 (2022)
Metabolomics investigates global metabolic alterations associated with chemical, biological, physiological, or pathological processes. These metabolic changes are measured with various analytical platforms including liquid chromatography-mass spectro
Externí odkaz:
https://doaj.org/article/9204305b347948d09a1d0650b76917f1
Publikováno v:
mSystems, Vol 5, Iss 2 (2020)
ABSTRACT The reactive intermediate deaminase RidA (EC 3.5.99.10) is conserved across all domains of life and deaminates reactive enamine species. When Salmonella enterica ridA mutants are grown in minimal medium, 2-aminoacrylate (2AA) accumulates, da
Externí odkaz:
https://doaj.org/article/40280bad67c446c1aa128e306c7065e7
Autor:
Rahil Taujale, Aarya Venkat, Liang-Chin Huang, Zhongliang Zhou, Wayland Yeung, Khaled M Rasheed, Sheng Li, Arthur S Edison, Kelley W Moremen, Natarajan Kannan
Publikováno v:
eLife, Vol 9 (2020)
Glycosyltransferases (GTs) are prevalent across the tree of life and regulate nearly all aspects of cellular functions. The evolutionary basis for their complex and diverse modes of catalytic functions remain enigmatic. Here, based on deep mining of
Externí odkaz:
https://doaj.org/article/3af3aed9f09e483db012d4bc7e1b0006
Publikováno v:
Annals of the New York Academy of Sciences. 1521:155-162
Autor:
Maxwell B Colonna, Tonya Moss, Sneha Mokashi, Sujata Srikanth, Julie R Jones, Jackson R Foley, Cindy Skinner, Angie Lichty, Anthony Kocur, Tim Wood, Tracy Murray Stewart, Robert A Casero Jr., Heather Flanagan-Steet, Arthur S Edison, Michael J Lyons, Richard Steet
Publikováno v:
Human Molecular Genetics. 32:732-744
Mono- and bi-allelic variants in ALDH18A1 cause a spectrum of human disorders associated with cutaneous and neurological findings that overlap with both cutis laxa and spastic paraplegia. ALDH18A1 encodes the bifunctional enzyme pyrroline-5-carboxyla