Zobrazeno 1 - 10
of 2 563
pro vyhledávání: '"A S, Reis"'
Autor:
Kamila R. Abreu, Jailton R. Viana, João G. Oliveira Neto, Tatielle G. Dias, Aramys S. Reis, Mateus R. Lage, Luzeli M. da Silva, Francisco F. de Sousa, Adenilson O. dos Santos
Publikováno v:
ACS Omega, Vol 9, Iss 43, Pp 43488-43502 (2024)
Externí odkaz:
https://doaj.org/article/d0aba1760e1b4db48dcef3c2f0fac0d8
Autor:
Chiara Maria Lavinia Loeffler, Omar S. M. El Nahhas, Hannah Sophie Muti, Zunamys I. Carrero, Tobias Seibel, Marko van Treeck, Didem Cifci, Marco Gustav, Kevin Bretz, Nadine T. Gaisa, Kjong-Van Lehmann, Alexandra Leary, Pier Selenica, Jorge S. Reis-Filho, Nadina Ortiz-Bruechle, Jakob Nikolas Kather
Publikováno v:
BMC Biology, Vol 22, Iss 1, Pp 1-14 (2024)
Abstract Background Homologous recombination deficiency (HRD) is recognized as a pan-cancer predictive biomarker that potentially indicates who could benefit from treatment with PARP inhibitors (PARPi). Despite its clinical significance, HRD testing
Externí odkaz:
https://doaj.org/article/003303862b20434e84941368c6c014a7
Autor:
Manisha Jalan, Aman Sharma, Xin Pei, Nils Weinhold, Erika S. Buechelmaier, Yingjie Zhu, Sana Ahmed-Seghir, Abhirami Ratnakumar, Melody Di Bona, Niamh McDermott, Joan Gomez-Aguilar, Kyrie S. Anderson, Charlotte K. Y. Ng, Pier Selenica, Samuel F. Bakhoum, Jorge S. Reis-Filho, Nadeem Riaz, Simon N. Powell
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-17 (2024)
Abstract Collisions of the transcription and replication machineries on the same DNA strand can pose a significant threat to genomic stability. These collisions occur in part due to the formation of RNA-DNA hybrids termed R-loops, in which a newly tr
Externí odkaz:
https://doaj.org/article/7cd61270c6534754a1bbd7203bce046c
Autor:
Yingjie Zhu, Xin Pei, Ardijana Novaj, Jeremy Setton, Daniel Bronder, Fatemeh Derakhshan, Pier Selenica, Niamh McDermott, Mehmet Orman, Sarina Plum, Shyamal Subramanyan, Sara H. Braverman, Biko McMillan, Sonali Sinha, Jennifer Ma, Andrea Gazzo, Atif Khan, Samuel Bakhoum, Simon N. Powell, Jorge S. Reis-Filho, Nadeem Riaz
Publikováno v:
Genome Medicine, Vol 16, Iss 1, Pp 1-17 (2024)
Abstract Background Pathogenic BRCA1 or BRCA2 germline mutations contribute to hereditary breast, ovarian, prostate, and pancreatic cancer. Paradoxically, bi-allelic inactivation of BRCA1 or BRCA2 (bBRCA1/2) is embryonically lethal and decreases cell
Externí odkaz:
https://doaj.org/article/a99e307f304a411b854e096a6e780f20
Autor:
Cassiano Gustavo Messias, Cláudio A. de Almeida, Daniel E. Silva, Luciana S. Soler, Luis E. Maurano, Vagner L. Camilotti, Fábio C. Alves, Libério J. da Silva, Mariane S. Reis, Thiago C. de Lima, Vivian Renó, Deborah L. C. Lima, Amanda P. Belluzzo, Camila B. Quadros, Delmina C. M. Barradas, Douglas R. V. de Moraes, Eduardo F. M. Bastos, Igor P. Cunha, Jefferson J. de Souza, Lucélia S. de Barros, Luiz Henrique A. Gusmão, Rodrigo de Almeida, Dayane R. V. de Moraes, Diego M. Silva, Eduardo H. S. Chrispim, João Felipe S. K. C. Pinto, Manoel R. Ribeiro Neto, Marlon Henrique H. Matos, Noeli Aline P. Moreira, Raíssa C. dos S. Teixeira, Gabriel M. R. Alves, Ana Carolina S. de Andrade, Letícia P. Perez, Bruna Maria P. Bento, Hugo C. de Castro Filho, Igor S. dos Santos, Liliane Cristina L. de Araújo, Maira Matias, Murilo B. da Silva, Fábio da C. Pinheiro, André Carvalho, Haron Xaud, Maristela Xaud, Ana Paula Matos, Luis Baumann, Elaine B. da Silva, Laerte Guimarães Ferreira, Marcos Adami
Publikováno v:
Communications Earth & Environment, Vol 5, Iss 1, Pp 1-9 (2024)
Abstract The Brazilian Amazon Satellite Monitoring Program (PRODES Amazonia) tracks forest loss in the Brazilian Amazon but excludes about 6.6% ( ~ 280,000 km²) of non-forest vegetation (NF). Here we developed the PRODES NF system to address this ga
Externí odkaz:
https://doaj.org/article/a655e299e61548afabef5b4430ea81cc
Autor:
Steffi Oesterreich, Leigh Pate, Adrian V. Lee, Fangyuan Chen, Rachel C. Jankowitz, Rita Mukhtar, Otto Metzger, Matthew J. Sikora, Christopher I. Li, Christos Sotiriou, Osama S. Shah, Thijs Koorman, Gary Ulaner, Jorge S. Reis-Filho, Nancy M. Davidson, Karen Van Baelen, Laurie Hutcheson, Siobhan Freeney, Flora Migyanka, Claire Turner, Patrick Derksen, Todd Bear, Christine Desmedt
Publikováno v:
npj Breast Cancer, Vol 10, Iss 1, Pp 1-7 (2024)
Abstract There is growing awareness of the unique etiology, biology, and clinical presentation of invasive lobular breast cancer (ILC), but additional research is needed to ensure translation of findings into management and treatment guidelines. We c
Externí odkaz:
https://doaj.org/article/674206de519c4c9a91765a34839d5098
Autor:
Adriane S. Reis, Laurita dos Santos, Américo Cunha Jr, Thaís C.R.O. Konstantyner, Elbert E.N. Macau
Publikováno v:
Infectious Disease Modelling, Vol 9, Iss 2, Pp 314-328 (2024)
Since the COVID-19 pandemic was first reported in 2019, it has rapidly spread around the world. Many countries implemented several measures to try to control the virus spreading. The healthcare system and consequently the general quality of life popu
Externí odkaz:
https://doaj.org/article/95e2f7d5a1794dc7973eb50419f04f82
Autor:
Marinaldo V. Souza Junior, João G. Oliveira Neto, Walajhone O. Pereira, Jéssica A.O. Rodrigues, Jailton R. Viana, Aramys S. Reis, Mateus R. Lage, Guilherme G.C. Carvalho, Cláudia O. Pessoa, Adenilson O. dos Santos, Francisco F. de Sousa
Publikováno v:
Heliyon, Vol 10, Iss 20, Pp e37505- (2024)
This study reports additional information's of geometric, electronic, thermodynamic, and vibrational properties of a Cu(II) complex with 1,10-phenanthroline and L-glutamine ligands. The experimental spectroscopic analyses were corroborated by density
Externí odkaz:
https://doaj.org/article/d751564545c24adc800d5023c1e6815a
Autor:
Ingrid Marins de Almeida, Bruna Ramos Tosta, Laiane da Cruz Pena, Hatilla dos Santos Silva, Fabiane S. Reis-Goes, Nívia N. Silva, João Victor Andrade Cruz, Mailane dos Anjos Silva, Jéssica Francisco de Araújo, Juliana Lopes Rodrigues, Gabriella Oliveira, Ricardo Gassmann Figueiredo, Sara Nunes Vaz, Iris Montaño-Castellón, Daniele Santana, Alex Torres, Fabyan Esberard de Lima Beltrão, Valdirene Leão Carneiro, Gubio Soares Campos, Carlos Brites, Vitor Fortuna, Camila Alexandrina Figueiredo, Soraya Castro Trindade, Helton Estrela Ramos, Ryan dos Santos Costa
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
IntroductionThe COVID-19, triggered by the SARS-CoV-2 virus, has varied clinical manifestations, ranging from mild cases to severe forms such as fatal pneumonia and acute respiratory distress syndrome (ARDS). Disease severity is influenced by an exac
Externí odkaz:
https://doaj.org/article/29ffd175700b45c0926e6f60fc5747ac
Autor:
Meredith S. Pelster, Ian M. Silverman, Joseph D. Schonhoft, Adrienne Johnson, Pier Selenica, Danielle Ulanet, Victoria Rimkunas, Jorge S. Reis-Filho
Publikováno v:
npj Precision Oncology, Vol 8, Iss 1, Pp 1-7 (2024)
Abstract Pancreatic acinar cell carcinoma (PACC) is a rare form of pancreatic cancer that commonly harbors targetable alterations, including activating fusions in the MAPK pathway and loss-of-function (LOF) alterations in DNA damage response/homologo
Externí odkaz:
https://doaj.org/article/28525c8399254240bf4adf2e72e958ea