Zobrazeno 1 - 10
of 249
pro vyhledávání: '"A S, McColl"'
Publikováno v:
Physiological Reports, Vol 12, Iss 18, Pp n/a-n/a (2024)
Abstract Extracellular vesicle (EV) cargo is known to change in response to stimuli such as muscle damage. This study aimed to assess particle size, concentration and microRNA (miR) content within small EV‐enriched separations prepared from human b
Externí odkaz:
https://doaj.org/article/4994c995e7e54a68a2f7ee0946ae19be
Autor:
Gary Wildey, Ashley M. Shay, Karen S. McColl, Suzy Yoon, Mohammad A. Shatat, Ahmad Perwez, Kyle B. Spainhower, Adam M. Kresak, MaryBeth Lipka, Michael Yang, Mohadese Behtaj, Pingfu Fu, Asrar Alahmadi, Wadad Mneimneh, Ata Abbas, Afshin Dowlati
Publikováno v:
Molecular Cancer Therapeutics. 22:264-273
The canonical model of “small cell lung cancer” (SCLC) depicts tumors arising from dual inactivation of TP53 and RB1. However, many genomic studies have persistently identified tumors with no RB1 mutations. Here, we examined RB1 protein expressio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f4c86a83b730dfa552956cd55e68734
https://doi.org/10.1158/1535-7163.mct-22-0365
https://doi.org/10.1158/1535-7163.mct-22-0365
Autor:
Afshin Dowlati, Ata Abbas, Wadad Mneimneh, Asrar Alahmadi, Pingfu Fu, Mohadese Behtaj, Michael Yang, MaryBeth Lipka, Adam M. Kresak, Kyle B. Spainhower, Ahmad Perwez, Mohammad A. Shatat, Suzy Yoon, Karen S. McColl, Ashley M. Shay, Gary Wildey
Supplementary Tables
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c1f7d4df3b05d341bd589cf3a47e758
https://doi.org/10.1158/1535-7163.22523419.v1
https://doi.org/10.1158/1535-7163.22523419.v1
Autor:
Afshin Dowlati, Ata Abbas, Wadad Mneimneh, Asrar Alahmadi, Pingfu Fu, Mohadese Behtaj, Michael Yang, MaryBeth Lipka, Adam M. Kresak, Kyle B. Spainhower, Ahmad Perwez, Mohammad A. Shatat, Suzy Yoon, Karen S. McColl, Ashley M. Shay, Gary Wildey
Supplementary Figures
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::525650c2b519933fc2330b6b23a033e0
https://doi.org/10.1158/1535-7163.22523413.v1
https://doi.org/10.1158/1535-7163.22523413.v1
Autor:
Tian He, Kyle Spainhower, Aik Choon Tan, Michael Yang, Adam Kresak, Gary Wildey, Afshin Dowlati, Karen S. McColl, Alyssa Savadelis, Cassidy McColl, Ata Abbas
Publikováno v:
Molecular Oncology, Vol 15, Iss 1, Pp 195-209 (2021)
Molecular Oncology
Molecular Oncology
RUNX1T1 is highly expressed in ‘combined’ and ‘pure’ SCLC via genetic amplification or greater transcription, respectively. RUNX1T1 interacts with the CDKN1A (p21) promoter and is associated with reduced histone H3 acetylation, resulting in d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::416e9251fa83d5b5e85f0621348979c8
https://doi.org/10.1002/1878-0261.12829
https://doi.org/10.1002/1878-0261.12829
Autor:
Andrew R, Lavik, Karen S, McColl, Fernanda O, Lemos, Martijn, Kerkhofs, Fei, Zhong, Michael, Harr, Daniela, Schlatzer, Kozo, Hamada, Katsuhiko, Mikoshiba, Francesco, Crea, Geert, Bultynck, Martin D, Bootman, Jan B, Parys, Clark W, Distelhorst
Publikováno v:
Biochimica et biophysica acta. Molecular cell research. 1869(4)
Pyruvate kinase isoform M2 (PKM2) is a rate-limiting glycolytic enzyme that is widely expressed in embryonic tissues. The expression of PKM2 declines in some tissues following embryogenesis, while other pyruvate kinase isozymes are upregulated. Howev
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::81140f3336f24c93f24fb225396e384c
https://pubmed.ncbi.nlm.nih.gov/35026348
https://pubmed.ncbi.nlm.nih.gov/35026348
Publikováno v:
Molecular Oncology, Vol 12, Iss 12, Pp 2124-2135 (2018)
Molecular Oncology
Molecular Oncology
Protein inhibitor of activated STAT3 (PIAS3) is an endogenous suppressor of signal transducer and activator of transcription 3 (STAT3) signaling. By directly interacting with phosphorylated STAT3, PIAS3 can block the downstream transcriptional activi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae5c6923499c7b4222851a8b125aa54c
https://doaj.org/article/a3988cfdc09d478c9d6d31c835834c30
https://doaj.org/article/a3988cfdc09d478c9d6d31c835834c30
Autor:
Andrew R. Lavik, Karen S. McColl, Fernanda O. Lemos, Martijn Kerkhofs, Fei Zhong, Michael Harr, Daniela Schlatzer, Kozo Hamada, Katsuhiko Mikoshiba, Francesco Crea, Geert Bultynck, Martin D. Bootman, Jan B. Parys, Clark W. Distelhorst
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Molecular Cell Research. 1869:119206
Pyruvate kinase isoform M2 (PKM2) is a rate-limiting glycolytic enzyme that is widely expressed in embryonic tissues. The expression of PKM2 declines in some tissues following embryogenesis, while other pyruvate kinase isozymes are upregulated. Howev
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::79297f172d870149cd2aa4c6e6492530
https://doi.org/10.1016/j.bbamcr.2021.119206
https://doi.org/10.1016/j.bbamcr.2021.119206
Autor:
Vamsidhar Velcheti, Adam Kresak, Pingfu Fu, Karen S. McColl, Yanwen Chen, Gary Wildey, Afshin Dowlati, Mary Beth Lipka, Mohadese Behtaj, Michael Yang, Nneha Sakre
Publikováno v:
Oncotarget
// Karen McColl 1 , Gary Wildey 1 , Nneha Sakre 1 , Mary Beth Lipka 1 , Mohadese Behtaj 2 , Adam Kresak 3 , Yanwen Chen 4 , Michael Yang 2 , Vamsidhar Velcheti 5 , Pingfu Fu 4 and Afshin Dowlati 6 1 Division of Hematology and Oncology, Case Western R
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c1a0bb5f8ab514eb63d7dc371b24621b
http://europepmc.org/articles/PMC5650296
http://europepmc.org/articles/PMC5650296
Autor:
Gary Wildey, Pingfu Fu, Neelesh Sharma, Karen S. McColl, A. Miron, Mary Beth Lipka, Afshin Dowlati, Adam Kresak, Michael Yang, Snehal Dabir, Mohadese Behtaj
Publikováno v:
Annals of Oncology. 27:642-647
Background Genomic studies in small-cell lung cancer (SCLC) lag far behind those carried out in nonsmall-cell lung cancer (NSCLC). To date, most SCLC studies have evaluated patients with surgically resectable disease. Here we sought to evaluate the g
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06a9d819b4dc7e7b72704f72cbb6efa5
https://doi.org/10.1093/annonc/mdw005
https://doi.org/10.1093/annonc/mdw005