Zobrazeno 1 - 10
of 101
pro vyhledávání: '"A S, McCallion"'
Autor:
Marah H. Wahbeh, Rachel J. Boyd, Christian Yovo, Bailey Rike, Andrew S. McCallion, Dimitrios Avramopoulos
Publikováno v:
HGG Advances, Vol 5, Iss 3, Pp 100303- (2024)
Summary: Recent collaborative genome-wide association studies (GWAS) have identified >200 independent loci contributing to risk for schizophrenia (SCZ). The genes closest to these loci have diverse functions, supporting the potential involvement of m
Externí odkaz:
https://doaj.org/article/e490de029ed9412cbb9e4e5f845774f3
Autor:
Rachel J. Boyd, Sarah A. McClymont, Nelson B. Barrientos, Paul W. Hook, William D. Law, Rebecca J. Rose, Eric L. Waite, Jay Rathinavelu, Dimitrios Avramopoulos, Andrew S. McCallion
Publikováno v:
BMC Genomics, Vol 24, Iss 1, Pp 1-18 (2023)
Abstract To overcome the ethical and technical limitations of in vivo human disease models, the broader scientific community frequently employs model organism-derived cell lines to investigate disease mechanisms, pathways, and therapeutic strategies.
Externí odkaz:
https://doaj.org/article/026f85d2ff5a46fca1232db9779e406c
Publikováno v:
Journal of Neuroinflammation, Vol 19, Iss 1, Pp 1-20 (2022)
Abstract Multifactorial diseases are characterized by inter-individual variation in etiology, age of onset, and penetrance. These diseases tend to be relatively common and arise from the combined action of genetic and environmental factors; however,
Externí odkaz:
https://doaj.org/article/3898560943bc4ba1a5fd657cbd35d2ad
Autor:
J. Gumbel, L. Megner, O. M. Christensen, N. Ivchenko, D. P. Murtagh, S. Chang, J. Dillner, T. Ekebrand, G. Giono, A. Hammar, J. Hedin, B. Karlsson, M. Krus, A. Li, S. McCallion, G. Olentšenko, S. Pak, W. Park, J. Rouse, J. Stegman, G. Witt
Publikováno v:
Atmospheric Chemistry and Physics, Vol 20, Pp 431-455 (2020)
Global three-dimensional data are a key to understanding gravity waves in the mesosphere and lower thermosphere. MATS (Mesospheric Airglow/Aerosol Tomography and Spectroscopy) is a new Swedish satellite mission that addresses this need. It applies sp
Externí odkaz:
https://doaj.org/article/910d7eae64c74ebd9ace69ebf0c118bb
Autor:
ThuyVy Duong, Rebecca Rose, Adriana Blazeski, Noah Fine, Courtney E. Woods, Joseph F. Thole, Nona Sotoodehnia, Elsayed Z. Soliman, Leslie Tung, Andrew S. McCallion, Dan E. Arking
Publikováno v:
Disease Models & Mechanisms, Vol 14, Iss 8 (2021)
Clinically pertinent electrocardiogram (ECG) data from model systems, such as zebrafish, are crucial for illuminating factors contributing to human cardiac electrophysiological abnormalities and disease. Current zebrafish ECG collection strategies ha
Externí odkaz:
https://doaj.org/article/91bf522f3be94c878d1d046719b0bb10
Autor:
Sarah Edie, Norann A. Zaghloul, Carmen C. Leitch, Donna K. Klinedinst, Janette Lebron, Joey F. Thole, Andrew S. McCallion, Nicholas Katsanis, Roger H. Reeves
Publikováno v:
G3: Genes, Genomes, Genetics, Vol 8, Iss 7, Pp 2215-2223 (2018)
Trisomy for human chromosome 21 (Hsa21) results in Down syndrome (DS), one of the most genetically complex conditions compatible with human survival. Assessment of the physiological consequences of dosage-driven overexpression of individual Hsa21 gen
Externí odkaz:
https://doaj.org/article/6168517f327c468db0ddd5203f20a442
Autor:
Elisabeth Gillis, Ajay A. Kumar, Ilse Luyckx, Christoph Preuss, Elyssa Cannaerts, Gerarda van de Beek, Björn Wieschendorf, Maaike Alaerts, Nikhita Bolar, Geert Vandeweyer, Josephina Meester, Florian Wünnemann, Russell A. Gould, Rustam Zhurayev, Dmytro Zerbino, Salah A. Mohamed, Seema Mital, Luc Mertens, Hanna M. Björck, Anders Franco-Cereceda, Andrew S. McCallion, Lut Van Laer, Judith M. A. Verhagen, Ingrid M. B. H. van de Laar, Marja W. Wessels, Emmanuel Messas, Guillaume Goudot, Michaela Nemcikova, Alice Krebsova, Marlies Kempers, Simone Salemink, Toon Duijnhouwer, Xavier Jeunemaitre, Juliette Albuisson, Per Eriksson, Gregor Andelfinger, Harry C. Dietz, Aline Verstraeten, Bart L. Loeys, Mibava Leducq Consortium
Publikováno v:
Frontiers in Physiology, Vol 8 (2017)
Externí odkaz:
https://doaj.org/article/00bba679614b4010927e1186b126fa61
Autor:
Elisabeth Gillis, Ajay A. Kumar, Ilse Luyckx, Christoph Preuss, Elyssa Cannaerts, Gerarda van de Beek, Björn Wieschendorf, Maaike Alaerts, Nikhita Bolar, Geert Vandeweyer, Josephina Meester, Florian Wünnemann, Russell A. Gould, Rustam Zhurayev, Dmytro Zerbino, Salah A. Mohamed, Seema Mital, Luc Mertens, Hanna M. Björck, Anders Franco-Cereceda, Andrew S. McCallion, Lut Van Laer, Judith M. A. Verhagen, Ingrid M. B. H. van de Laar, Marja W. Wessels, Emmanuel Messas, Guillaume Goudot, Michaela Nemcikova, Alice Krebsova, Marlies Kempers, Simone Salemink, Toon Duijnhouwer, Xavier Jeunemaitre, Juliette Albuisson, Per Eriksson, Gregor Andelfinger, Harry C. Dietz, Aline Verstraeten, Bart L. Loeys, Mibava Leducq Consortium
Publikováno v:
Frontiers in Physiology, Vol 8 (2017)
Bicuspid aortic valve (BAV) is the most common congenital heart defect. Although many BAV patients remain asymptomatic, at least 20% develop thoracic aortic aneurysm (TAA). Historically, BAV-related TAA was considered as a hemodynamic consequence of
Externí odkaz:
https://doaj.org/article/eaa6fdcd9b7a4bbd9409b17748a5090d
Autor:
Nicole Eckart, Qifeng Song, Rebecca Yang, Ruihua Wang, Heng Zhu, Andrew S McCallion, Dimitrios Avramopoulos
Publikováno v:
PLoS ONE, Vol 11, Iss 6, p e0157086 (2016)
Calcium channel subunits, including CACNA1C, have been associated with multiple psychiatric disorders. Specifically, genome wide association studies (GWAS) have repeatedly identified the single nucleotide polymorphism (SNP) rs1006737 in intron 3 of C
Externí odkaz:
https://doaj.org/article/84af6b43c1ef4dceb38218a169536433
Autor:
Pamela J. McLean, Paul W. Hook, Loyal A. Goff, Wolfdieter Springer, Zbigniew K. Wszolek, Rebecca R. Valentino, Catherine Labbé, Patrick W. Johnson, Andrew S. McCallion, Ryan J. Uitti, Michael G. Heckman, Alexandra I. Soto-Beasley, Ronald L. Walton, Owen A. Ross
Publikováno v:
Parkinsonism Relat Disord
Introduction The microtubule-associated protein tau (MAPT) gene is considered a strong genetic risk factor for Parkinson's disease (PD) in Caucasians. MAPT is located within an inversion region of high linkage disequilibrium designated as H1 and H2 h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01273b693e4214678025b945c50f38c1
https://doi.org/10.1016/j.parkreldis.2020.07.022
https://doi.org/10.1016/j.parkreldis.2020.07.022