Zobrazeno 1 - 10
of 815
pro vyhledávání: '"A S, Kibel"'
Autor:
Hui-Yi Lin, Harun Mazumder, Indrani Sarkar, Po-Yu Huang, Rosalind A. Eeles, Zsofia Kote-Jarai, Kenneth R. Muir, UKGPCS collaborators, Johanna Schleutker, Nora Pashayan, Jyotsna Batra, APCB (Australian Prostate Cancer BioResource), David E. Neal, Sune F. Nielsen, Børge G. Nordestgaard, Henrik Grönberg, Fredrik Wiklund, Robert J. MacInnis, Christopher A. Haiman, Ruth C. Travis, Janet L. Stanford, Adam S. Kibel, Cezary Cybulski, Kay-Tee Khaw, Christiane Maier, Stephen N. Thibodeau, Manuel R. Teixeira, Lisa Cannon-Albright, Hermann Brenner, Radka Kaneva, Hardev Pandha, The PRACTICAL consortium, Jong Y. Park
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-14 (2024)
Abstract Single nucleotide polymorphism (SNP) interactions are the key to improving polygenic risk scores. Previous studies reported several significant SNP–SNP interaction pairs that shared a common SNP to form a cluster, but some identified pairs
Externí odkaz:
https://doaj.org/article/f6d6e2ec91c84df5bee4f5f2c347d676
Autor:
Meghana S. Pagadala, Asona J. Lui, Allison Y. Zhong, Julie A. Lynch, Roshan Karunamuni, Kyung Min Lee, Anna Plym, Brent S. Rose, Hannah K. Carter, Adam S. Kibel, Scott L. DuVall, J. Michael Gaziano, Matthew S. Panizzon, Richard L. Hauger, Tyler M. Seibert
Publikováno v:
Acta Oncologica, Vol 63, Iss 1 (2024)
Background: The US government considers veterans to have been exposed to Agent Orange if they served in Vietnam while the carcinogen was in use, and these veterans are often deemed at high risk of prostate cancer (PCa). Here, we assess whether presum
Externí odkaz:
https://doaj.org/article/4271ec4c5c6742b9ac52d13f2ba0e5ce
Autor:
Andrés Camacho, Fatima Salah, Camden P. Bay, Jonathan Waring, Renato Umeton, Michelle S. Hirsch, Alexander P. Cole, Adam S. Kibel, Massimo Loda, Clare M. Tempany, Fiona M. Fennessy
Publikováno v:
BJUI Compass, Vol 4, Iss 4, Pp 473-481 (2023)
Abstract Rationale and objectives The study aims to propose an optimal workflow in patients with a PI‐RADS 3 (PR‐3) assessment category (AC) through determining the timing and type of pathology interrogation used for the detection of clinically s
Externí odkaz:
https://doaj.org/article/3b8230abaeff42dfbb3c80fcff5d522a
Autor:
James Yarmolinsky, Jamie W. Robinson, Daniela Mariosa, Ville Karhunen, Jian Huang, Niki Dimou, Neil Murphy, Kimberley Burrows, Emmanouil Bouras, Karl Smith-Byrne, Sarah J. Lewis, Tessel E. Galesloot, Lambertus A. Kiemeney, Sita Vermeulen, Paul Martin, Demetrius Albanes, Lifang Hou, Polly A. Newcomb, Emily White, Alicja Wolk, Anna H. Wu, Loïc Le Marchand, Amanda I. Phipps, Daniel D. Buchanan, Sizheng Steven Zhao, Dipender Gill, Stephen J. Chanock, Mark P. Purdue, George Davey Smith, Paul Brennan, Karl-Heinz Herzig, Marjo-Riitta Järvelin, Chris I. Amos, Rayjean J. Hung, Abbas Dehghan, Mattias Johansson, Marc J. Gunter, Kostas K. Tsilidis, Richard M. Martin, Maria Teresa Landi, Victoria Stevens, Ying Wang, Demetrios Albanes, Neil Caporaso, Christopher I. Amos, Sanjay Shete, Heike Bickeböller, Angela Risch, Richard Houlston, Stephen Lam, Adonina Tardon, Chu Chen, Stig E. Bojesen, H-Erich Wichmann, David Christiani, Gadi Rennert, Susanne Arnold, John K. Field, Loic Le Marchand, Olle Melander, Hans Brunnström, Geoffrey Liu, Angeline Andrew, Hongbing Shen, Shan Zienolddiny, Kjell Grankvist, Mikael Johansson, M. Dawn Teare, Yun-Chul Hong, Jian-Min Yuan, Philip Lazarus, Matthew B. Schabath, Melinda C. Aldrich, Rosalind A. Eeles, Christopher A. Haiman, Zsofia Kote-Jarai, Fredrick R. Schumacher, Sara Benlloch, Ali Amin Al Olama, Kenneth R. Muir, Sonja I. Berndt, David V. Conti, Fredrik Wiklund, Stephen Chanock, Catherine M. Tangen, Jyotsna Batra, Judith A. Clements, Henrik Grönberg, Nora Pashayan, Johanna Schleutker, Stephanie J. Weinstein, Catharine M.L. West, Lorelei A. Mucci, Géraldine Cancel-Tassin, Stella Koutros, Karina Dalsgaard Sørensen, Eli Marie Grindedal, David E. Neal, Freddie C. Hamdy, Jenny L. Donovan, Ruth C. Travis, Robert J. Hamilton, Sue Ann Ingles, Barry S. Rosenstein, Yong-Jie Lu, Graham G. Giles, Robert J. MacInnis, Adam S. Kibel, Ana Vega, Manolis Kogevinas, Kathryn L. Penney, Jong Y. Park, Janet L. Stanfrod, Cezary Cybulski, Børge G. Nordestgaard, Sune F. Nielsen, Hermann Brenner, Christiane Maier, Christopher J. Logothetis, Esther M. John, Manuel R. Teixeira, Susan L. Neuhausen, Kim De Ruyck, Azad Razack, Lisa F. Newcomb, Davor Lessel, Radka Kaneva, Nawaid Usmani, Frank Claessens, Paul A. Townsend, Jose Esteban Castelao, Monique J. Roobol, Florence Menegaux, Kay-Tee Khaw, Lisa Cannon-Albright, Hardev Pandha, Stephen N. Thibodeau, David J. Hunter, Peter Kraft, William J. Blot, Elio Riboli
Publikováno v:
EBioMedicine, Vol 100, Iss , Pp 104991- (2024)
Summary: Background: Tumour-promoting inflammation is a “hallmark” of cancer and conventional epidemiological studies have reported links between various inflammatory markers and cancer risk. The causal nature of these relationships and, thus, th
Externí odkaz:
https://doaj.org/article/76559893532a492cbb3d1275b22f7ce4
Autor:
Thomas Seisen, Muhieddine Labban, Stuart R. Lipsitz, Mark A. Preston, Matthew Mossanen, Joaquim Bellmunt, Morgan Rouprêt, Toni K. Choueiri, Adam S. Kibel, Maxine Sun, Quoc-Dien Trinh
Publikováno v:
Current Oncology, Vol 30, Iss 2, Pp 1986-1998 (2023)
Background: Since tobacco smoking represents the most established risk factor for bladder cancer, we sought to assess the ecological association between tobacco smoking prevalence and bladder cancer incidence and to contrast it with lung cancer. Meth
Externí odkaz:
https://doaj.org/article/62ed46b107c647228bb289ab9ab020ba
Autor:
Takuya Tsujino, Tomoaki Takai, Kunihiko Hinohara, Fu Gui, Takeshi Tsutsumi, Xiao Bai, Chenkui Miao, Chao Feng, Bin Gui, Zsofia Sztupinszki, Antoine Simoneau, Ning Xie, Ladan Fazli, Xuesen Dong, Haruhito Azuma, Atish D. Choudhury, Kent W. Mouw, Zoltan Szallasi, Lee Zou, Adam S. Kibel, Li Jia
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-19 (2023)
Identifying prostate cancer patients who may respond well to PARP inhibitors is important for their success in the clinic. Here, using a genome-wide CRISPR-Cas9 knockout screen, the authors identify MMS22L as a biomarker for sensitivity to PARP inhib
Externí odkaz:
https://doaj.org/article/ae5f553e58e5416b821643fde0923364
Autor:
Milena Braga-Basaria, Thomas G Travison, Mary-Ellen Taplin, Alexander Lin, Alyssa B Dufour, Daniel Habtemariam, Paul L Nguyen, Adam S Kibel, Praful Ravi, Richelle Bearup, Hannah Kackley, Hussein Kafel, Kieran Reid, Thomas Storer, Donald C Simonson, Marie McDonnell, Shehzad Basaria
Publikováno v:
PLoS ONE, Vol 18, Iss 2, p e0281508 (2023)
Androgen deprivation therapy (ADT), a cornerstone of treatment for patients with locally advanced and metastatic prostate cancer, is associated with many adverse effects, including osteoporosis, sexual dysfunction, fatigue, and vasomotor symptoms. It
Externí odkaz:
https://doaj.org/article/4cf46102272e4122abe95a4588531750
Autor:
Fei Chen, Burcu F Darst, Ravi K Madduri, Alex A Rodriguez, Xin Sheng, Christopher T Rentsch, Caroline Andrews, Wei Tang, Adam S Kibel, Anna Plym, Kelly Cho, Mohamed Jalloh, Serigne Magueye Gueye, Lamine Niang, Olufemi J Ogunbiyi, Olufemi Popoola, Akindele O Adebiyi, Oseremen I Aisuodionoe-Shadrach, Hafees O Ajibola, Mustapha A Jamda, Olabode P Oluwole, Maxwell Nwegbu, Ben Adusei, Sunny Mante, Afua Darkwa-Abrahams, James E Mensah, Andrew Anthony Adjei, Halimatou Diop, Joseph Lachance, Timothy R Rebbeck, Stefan Ambs, J Michael Gaziano, Amy C Justice, David V Conti, Christopher A Haiman
Publikováno v:
eLife, Vol 11 (2022)
Background: We recently developed a multi-ancestry polygenic risk score (PRS) that effectively stratifies prostate cancer risk across populations. In this study, we validated the performance of the PRS in the multi-ancestry Million Veteran Program an
Externí odkaz:
https://doaj.org/article/357704951c834856af7fc63a759e4c2d
Autor:
Anneke Meyer, Alireza Mehrtash, Marko Rak, Oleksii Bashkanov, Bjoern Langbein, Alireza Ziaei, Adam S. Kibel, Clare M. Tempany, Christian Hansen, Junichi Tokuda
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-14 (2021)
Abstract Preoperative assessment of the proximity of critical structures to the tumors is crucial in avoiding unnecessary damage during prostate cancer treatment. A patient-specific 3D anatomical model of those structures, namely the neurovascular bu
Externí odkaz:
https://doaj.org/article/0b307645ba7c4525a5208fe3cfd85cda
Autor:
Lin Yang, Jung Ae Lee, Emily Heer, Claire Pernar, Graham A. Colditz, Ratna Pakpahan, Kellie R. Imm, Eric H. Kim, Robert L. Grubb, Kathleen Y. Wolin, Adam S. Kibel, Siobhan Sutcliffe
Publikováno v:
BMC Urology, Vol 21, Iss 1, Pp 1-14 (2021)
Abstract Background To examine one-year trajectories of urinary and sexual outcomes, and correlates of these trajectories, among prostate cancer patients treated by radical prostatectomy (RP). Methods Study participants were recruited from 2011 to 20
Externí odkaz:
https://doaj.org/article/4981a01b2b614bee9cbac26a114eec38