The impact of preceding convection on the development of Medicane Ianos and the sensitivity to sea surface temperature

Autor: C. Sánchez, S. Gray, A. Volonté, F. Pantillon, S. Berthou, S. Davolio

Publikováno v: Weather and Climate Dynamics, Vol 5, Pp 1429-1455 (2024)

Medicane Ianos in September 2020 was one of the strongest medicanes observed in the last 25 years. It was, like other medicanes, a very intense cyclone evolving from a baroclinic mid-latitude low into a tropical-like cyclone with an axisymmetric warm

Externí odkaz: https://doaj.org/article/7e0a9469440643439fad3a6758e87ed4

Enhancing circulatory myokines and extracellular vesicle uptake with targeted exercise in patients with prostate cancer (the MYEX trial): a single-group crossover study

Autor: Jin-Soo Kim, Dennis R. Taaffe, Daniel A. Galvão, Timothy D. Clay, Andrew D. Redfern, Elin S. Gray, Robert U. Newton

Publikováno v: BMC Cancer, Vol 24, Iss 1, Pp 1-7 (2024)

Abstract Introduction Physical activity is associated with improved disease progression and cancer-specific survival in patients with prostate cancer (PCa). However, the mechanisms underlying these associations remain unclear, while the relative impa

Externí odkaz: https://doaj.org/article/6526fa2a1d1f48f19bb60a8a65bf2bbd

Discovery of Potent Degraders of the Dengue Virus Envelope Protein

Autor: Zhengnian Li, Han‐Yuan Liu, Zhixiang He, Antara Chakravarty, Ryan P. Golden, Zixuan Jiang, Inchul You, Hong Yue, Katherine A. Donovan, Guangyan Du, Jianwei Che, Jason Tse, Isaac Che, Wenchao Lu, Eric S. Fischer, Tinghu Zhang, Nathanael S. Gray, Priscilla L. Yang

Publikováno v: Advanced Science, Vol 11, Iss 40, Pp n/a-n/a (2024)

Abstract Targeted protein degradation has been widely adopted as a new approach to eliminate both established and previously recalcitrant therapeutic targets. Here, it is reported that the development of small molecule degraders of the envelope (E) p

Externí odkaz: https://doaj.org/article/d886eb34b9c74a7eabd320cf5081d214

Spatial transcriptomics reveals discrete tumour microenvironments and autocrine loops within ovarian cancer subclones

Autor: Elena Denisenko, Leanne de Kock, Adeline Tan, Aaron B. Beasley, Maria Beilin, Matthew E. Jones, Rui Hou, Dáithí Ó Muirí, Sanela Bilic, G. Raj K. A. Mohan, Stuart Salfinger, Simon Fox, Khaing P. W. Hmon, Yen Yeow, Youngmi Kim, Rhea John, Tami S. Gilderman, Emily Killingbeck, Elin S. Gray, Paul A. Cohen, Yu Yu, Alistair R. R. Forrest

Publikováno v: Nature Communications, Vol 15, Iss 1, Pp 1-15 (2024)

Abstract High-grade serous ovarian carcinoma (HGSOC) is genetically unstable and characterised by the presence of subclones with distinct genotypes. Intratumoural heterogeneity is linked to recurrence, chemotherapy resistance, and poor prognosis. Her

Externí odkaz: https://doaj.org/article/e74fdf5a18e94838a46beb1421419119

In situ estimation of ice crystal properties at the South Pole using LED calibration data from the IceCube Neutrino Observatory

Autor: R. Abbasi, M. Ackermann, J. Adams, N. Aggarwal, J. Aguilar, M. Ahlers, M. Ahrens, J.-M. Alameddine, A. A. Alves Junior, N. M. B. Amin, K. Andeen, T. Anderson, G. Anton, C. Argüelles, Y. Ashida, S. Athanasiadou, S. Axani, X. Bai, A. Balagopal V, M. Baricevic, S. Barwick, V. Basu, R. Bay, J. Beatty, K. H. Becker, J. Becker Tjus, J. Beise, C. Bellenghi, S. Benda, S. BenZvi, D. Berley, E. Bernardini, D. Besson, G. Binder, D. Bindig, E. Blaufuss, S. Blot, F. Bontempo, J. Book, J. Borowka, C. Boscolo Meneguolo, S. Böser, O. Botner, J. Böttcher, E. Bourbeau, J. Braun, B. Brinson, J. Brostean-Kaiser, R. Burley, R. Busse, M. Campana, E. Carnie-Bronca, C. Chen, Z. Chen, D. Chirkin, K. Choi, B. Clark, L. Classen, A. Coleman, G. Collin, A. Connolly, J. Conrad, P. Coppin, P. Correa, S. Countryman, D. Cowen, R. Cross, C. Dappen, P. Dave, C. De Clercq, J. DeLaunay, D. Delgado López, H. Dembinski, K. Deoskar, A. Desai, P. Desiati, K. de Vries, G. de Wasseige, T. DeYoung, A. Diaz, J. C. Díaz-Vélez, M. Dittmer, H. Dujmovic, M. DuVernois, T. Ehrhardt, P. Eller, R. Engel, H. Erpenbeck, J. Evans, P. Evenson, K. L. Fan, A. Fazely, A. Fedynitch, N. Feigl, S. Fiedlschuster, A. Fienberg, C. Finley, L. Fischer, D. Fox, A. Franckowiak, E. Friedman, A. Fritz, P. Fürst, T. Gaisser, J. Gallagher, E. Ganster, A. Garcia, S. Garrappa, L. Gerhardt, A. Ghadimi, C. Glaser, T. Glüsenkamp, T. Glauch, N. Goehlke, J. Gonzalez, S. Goswami, D. Grant, S. Gray, T. Grégoire, S. Griswold, C. Günther, P. Gutjahr, C. Haack, A. Hallgren, R. Halliday, L. Halve, F. Halzen, H. Hamdaoui, M. Ha Minh, K. Hanson, J. Hardin, A. Harnisch, P. Hatch, A. Haungs, K. Helbing, J. Hellrung, F. Henningsen, L. Heuermann, S. Hickford, C. Hill, G. Hill, K. Hoffman, K. Hoshina, W. Hou, T. Huber, K. Hultqvist, M. Hünnefeld, R. Hussain, K. Hymon, S. In, N. Iovine, A. Ishihara, M. Jansson, G. Japaridze, M. Jeong, M. Jin, B. Jones, D. Kang, W. Kang, X. Kang, A. Kappes, D. Kappesser, L. Kardum, T. Karg, M. Karl, A. Karle, U. Katz, M. Kauer, J. Kelley, A. Kheirandish, K. Kin, J. Kiryluk, S. Klein, A. Kochocki, R. Koirala, H. Kolanoski, T. Kontrimas, L. Köpke, C. Kopper, J. Koskinen, P. Koundal, M. Kovacevich, M. Kowalski, T. Kozynets, E. Krupczak, E. Kun, N. Kurahashi, N. Lad, C. Lagunas Gualda, M. Larson, F. Lauber, J. Lazar, J. Lee, K. Leonard, A. Leszczyńska, M. Lincetto, Q. Liu, M. Liubarska, E. Lohfink, C. Love, C. J. Lozano Mariscal, L. Lu, F. Lucarelli, A. Ludwig, W. Luszczak, Y. Lyu, W. Y. Ma, J. Madsen, K. Mahn, Y. Makino, S. Mancina, W. Marie Sainte, I. Mariş, S. Marka, Z. Marka, M. Marsee, I. Martinez-Soler, R. Maruyama, T. McElroy, F. McNally, J. V. Mead, K. Meagher, S. Mechbal, A. Medina, M. Meier, S. Meighen-Berger, Y. Merckx, J. Micallef, D. Mockler, T. Montaruli, R. Moore, B. Morse, M. Moulai, T. Mukherjee, R. Naab, R. Nagai, U. Naumann, A. Nayerhoda, J. Necker, M. Neumann, H. Niederhausen, M. Nisa, S. Nowicki, A. Obertacke Pollmann, M. Oehler, B. Oeyen, A. Olivas, R. Orsoe, J. Osborn, E. O'Sullivan, H. Pandya, D. Pankova, N. Park, G. Parker, E. N. Paudel, L. Paul, C. Pérez de los Heros, L. Peters, J. Peterson, S. Philippen, S. Pieper, A. Pizzuto, M. Plum, Y. Popovych, A. Porcelli, M. Prado Rodriguez, B. Pries, R. Procter-Murphy, G. Przybylski, C. Raab, J. Rack-Helleis, M. Rameez, K. Rawlins, Z. Rechav, A. Rehman, P. Reichherzer, G. Renzi, E. Resconi, S. Reusch, W. Rhode, M. Richman, B. Riedel, E. Roberts, S. Robertson, S. Rodan, G. Roellinghoff, M. Rongen, C. Rott, T. Ruhe, L. Ruohan, D. Ryckbosch, D. Rysewyk Cantu, I. Safa, J. Saffer, D. Salazar-Gallegos, P. Sampathkumar, S. Sanchez Herrera, A. Sandrock, M. Santander, S. Sarkar, M. Schaufel, H. Schieler, S. Schindler, B. Schlüter, T. Schmidt, J. Schneider, F. Schröder, L. Schumacher, G. Schwefer, S. Sclafani, D. Seckel, S. Seunarine, A. Sharma, S. Shefali, N. Shimizu, M. Silva, B. Skrzypek, B. Smithers, R. Snihur, J. Soedingrekso, A. Søgaard, D. Soldin, C. Spannfellner, G. Spiczak, C. Spiering, M. Stamatikos, T. Stanev, R. Stein, T. Stezelberger, T. Stürwald, T. Stuttard, G. Sullivan, I. Taboada, S. Ter-Antonyan, W. Thompson, J. Thwaites, S. Tilav, K. Tollefson, C. Tönnis, S. Toscano, D. Tosi, A. Trettin, C. F. Tung, R. Turcotte, J. P. Twagirayezu, B. Ty, M. Unland Elorrieta, K. Upshaw, N. Valtonen-Mattila, J. Vandenbroucke, N. van Eijndhoven, D. Vannerom, J. van Santen, J. Vara, J. Veitch-Michaelis, S. Verpoest, D. Veske, C. Walck, W. Wang, T. B. Watson, C. Weaver, P. Weigel, A. Weindl, J. Weldert, C. Wendt, J. Werthebach, M. Weyrauch, N. Whitehorn, C. Wiebusch, N. Willey, D. Williams, M. Wolf, G. Wrede, J. Wulff, X. Xu, J. P. Yanez, E. Yildizci, S. Yoshida, S. Yu, T. Yuan, Z. Zhang, P. Zhelnin

Publikováno v: The Cryosphere, Vol 18, Pp 75-102 (2024)

The IceCube Neutrino Observatory instruments about 1 km3 of deep, glacial ice at the geographic South Pole. It uses 5160 photomultipliers to detect Cherenkov light emitted by charged relativistic particles. An unexpected light propagation effect obse

Externí odkaz: https://doaj.org/article/26f630cffc47491ebaac7cf7801c70c5