Zobrazeno 1 - 10
of 66
pro vyhledávání: '"A S, Estrera"'
Erythropoietin inhalation enhances adult canine alveolar-capillary formation following pneumonectomy
Autor:
Priya Ravikumar, Connie C.W. Hsia, Kytai T. Nguyen, Roshni Iyer, Dipendra Gyawali, Jyothi U. Menon, D. Merrill Dane, Cuneyt Yilmaz, Aaron S. Estrera
Publikováno v:
Am J Physiol Lung Cell Mol Physiol
Paracrine erythropoietin (EPO) signaling in the lung recruits endothelial progenitor cells, promotes cell maturation and angiogenesis, and is upregulated during canine postpneumonectomy (PNX) compensatory lung growth. To determine whether inhalationa
Autor:
Aaron S. Estrera, Connie C. W. Hsia, Cuneyt Yilmaz, Dipendra Gyawali, D. Merrill Dane, Roshni Iyer, Priya Ravikumar
Publikováno v:
Journal of Applied Physiology. 121:312-323
Following pneumonectomy (PNX), two separate mechanical forces act on the remaining lung: parenchymal stress caused by lung expansion, and microvascular distension and shear caused by increased perfusion. We previously showed that parenchymal stress a
Autor:
Cuneyt Yilmaz, Priya Ravikumar, D. Merrill Dane, Connie C. W. Hsia, Dennis J. Bellotto, Aaron S. Estrera
Publikováno v:
Journal of Applied Physiology. 116:816-824
Major lung resection is a robust model that mimics the consequences of loss-of-functioning lung units. We previously observed in adult canines, following 42% and 58% lung resection, a critical threshold of stimuli intensity for the initiation of comp
Autor:
D. Merrill Dane, Connie C. W. Hsia, Cuneyt Yilmaz, Priya Ravikumar, Aaron S. Estrera, Dennis J. Bellotto
Publikováno v:
Journal of Applied Physiology. 114:961-970
Following right pneumonectomy (PNX), the remaining lung expands and its perfusion more than doubles. Tissue and microvascular mechanical stresses are putative stimuli for compensatory lung growth and remodeling, but their relative contribution remain
Publikováno v:
Journal of Applied Physiology. 114:99-106
Following right pneumonectomy (PNX), the remaining lung expands and its perfusion doubles. Tissue and microvascular mechanical stresses are putative stimuli for initiating compensatory lung growth and remodeling, but their relative contributions to o
Autor:
Aaron S. Estrera, Connie C. W. Hsia, D. Merrill Dane, Harrieth Wagner, Robert L. Johnson, Peter D. Wagner
Publikováno v:
Journal of Applied Physiology. 104:1069-1079
We previously found that, following surgical resection of ∼58% of lung units by right pneumonectomy (PNX) in adult canines, oxygen-diffusing capacity (DlO2) fell sufficiently to become a major factor limiting exercise capacity, although the decline
Autor:
Connie C.W. Hsia, D. Merrill Dane, Harrieth Wagner, Eugene Y. Wu, Robert L. Johnson, Peter D. Wagner, Aaron S. Estrera
Publikováno v:
Journal of Applied Physiology. 103:1496-1505
In athletic animals the spleen induces acute polycythemia by dynamic contraction that releases red blood cells into the circulation in response to increased O2 demand and metabolic stress; when energy demand is relieved, the polycythemia is rapidly r
Autor:
Richard T. Hogg, D. Merrill Dane, Aaron S. Estrera, Deborah C. Hogg, Robert L. Johnson, Eugene Y. Wu, Connie C.W. Hsia
Publikováno v:
Journal of Applied Physiology. 101:289-297
The spleen acts as an erythrocyte reservoir in highly aerobic species such as the dog and horse. Sympathetic-mediated splenic contraction during exercise reversibly enhances convective O2 transport by increasing hematocrit, blood volume, and O2-carry
Autor:
Michelle C. Paul, David H. Rosenbaum, Aaron S. Estrera, Michael A. Wait, Shamsuddin Khwaja, J. Michael DiMaio, Rehal A. Bhojani
Publikováno v:
Chest. 128:246-249
Objectives Patients infected with HIV have an increased propensity for developing thoracic empyemas secondary to their susceptibility to polymicrobial pulmonary infections. We performed an assessment of the clinical outcomes of HIV patients undergoin
Autor:
Connie C.W. Hsia, Richard T. Hogg, Xiao Yan, Deborah C. Hogg, Robert L. Johnson, Aaron S. Estrera, Rahul M. Tamhane, D. Merrill Dane
Publikováno v:
Journal of Applied Physiology. 96:1090-1096
To determine whether all- trans retinoic acid (RA) treatment enhances lung function during compensatory lung growth in fully mature animals, adult male dogs ( n = 4) received 2 mg·kg-1·day-1po RA 4 days/wk beginning the day after right pneumonectom