Zobrazeno 1 - 10
of 922
pro vyhledávání: '"A S, Dimitrov"'
Autor:
Guillem Pascual-Pasto, Brendan McIntyre, Margaret G. Hines, Anna M. Giudice, Laura Garcia-Gerique, Jennifer Hoffmann, Pamela Mishra, Stephanie Matlaga, Simona Lombardi, Rawan Shraim, Patrick M. Schürch, Mark Yarmarkovich, Ted J. Hofmann, Fatemeh Alikarami, Daniel Martinez, Matthew Tsang, Luis Gil-de-Gómez, Timothy T. Spear, Kathrin M. Bernt, Adam J. Wolpaw, Dimiter S. Dimitrov, Wei Li, Kristopher R. Bosse
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-19 (2024)
Abstract Novel chimeric antigen receptor (CAR) T-cell approaches are needed to improve therapeutic efficacy in solid tumors. High-risk neuroblastoma is an aggressive pediatric solid tumor that expresses cell-surface GPC2 and GD2 with a tumor microenv
Externí odkaz:
https://doaj.org/article/b2ad4e5f753a46548b7df6730192b457
Autor:
Yulu Wang, Yifang Sun, Zhaoling Shen, Cong Wang, Jun Qian, Qiyu Mao, Yajie Wang, Wenping Song, Yu Kong, Changyou Zhan, Zhenguo Chen, Dimiter S. Dimitrov, Zhenlin Yang, Shibo Jiang, Fan Wu, Lu Lu, Tianlei Ying, Lei Sun, Yanling Wu
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-13 (2024)
Abstract Nipah virus infection, one of the top priority diseases recognized by the World Health Organization, underscores the urgent need to develop effective countermeasures against potential epidemics and pandemics. Here, we identify a fully human
Externí odkaz:
https://doaj.org/article/46eb885c817a4c7290a486dfc966cb8f
Autor:
Jiawei Zhang, Junjun Liu, Yali Yue, Lei Wang, Qunye He, Shuyi Xu, Junyan Li, Yunji Liao, Yu Chen, Shusheng Wang, Yueqing Xie, Baohong Zhang, Yanlin Bian, Dimiter S. Dimitrov, Yunsheng Yuan, Jianwei Zhu
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 43, Iss 1, Pp 1-18 (2024)
Abstract Background Though tamoxifen achieves success in treating estrogen receptor α (ERα)-positive breast cancer, the followed development of tamoxifen resistance is a common challenge in clinic. Signals downstream of prolactin receptor (PRLR) co
Externí odkaz:
https://doaj.org/article/c25ae8cc70c544b79719f5ae53eeff5a
Autor:
Xiaojie Chu, Seungmin Shin, Du-San Baek, Liyong Zhang, Alex Conard, Megan Shi, Ye-Jin Kim, Cynthia Adams, Maggie Hines, Xianglei Liu, Chuan Chen, Zehua Sun, Dontcho V. Jelev, John W. Mellors, Dimiter S. Dimitrov, Wei Li
Publikováno v:
mAbs, Vol 16, Iss 1 (2024)
Prostate stem cell antigen (PSCA) is expressed in all stages of prostate cancer, including in advanced androgen-independent tumors and bone metastasis. PSCA may associate with prostate carcinogenesis and lineage plasticity in prostate cancer. PSCA is
Externí odkaz:
https://doaj.org/article/1f085d6811ce4dcda8bde14f50a5302f
Autor:
R. S. Dimitrov
Publikováno v:
Bulgarian Journal of Veterinary Medicine, Vol 26, Iss 4, Pp 483-495 (2023)
The aim of the study was to provide diagnostic imaging data on rabbit prostate complex by means of magnetic resonance imaging (MRI) with regard to their use in morphological investigations of the gland. Six anaesthetised sexually mature clinically he
Externí odkaz:
https://doaj.org/article/4d2749dd5e3b47dca9365263234a8a44
Assessment of Novel Mesothelin-Specific Human Antibody Domain VH-Fc Fusion Proteins-Based PET Agents
Autor:
Zehua Sun, Ambika P. Jaswal, Xiaojie Chu, Harikrishnan Rajkumar, Angel G. Cortez, Robert Edinger, Max Rose, Anders Josefsson, Abhinav Bhise, Ziyu Huang, Rieko Ishima, John W Mellors, Dimiter S. Dimitrov, Wei Li, Jessie R. Nedrow
Publikováno v:
ACS Omega, Vol 8, Iss 46, Pp 43586-43595 (2023)
Externí odkaz:
https://doaj.org/article/60e4da078bb04806b5cc89b96027a3cd
Autor:
Yang Feng, Jaewon Lee, Liping Yang, Mary Beth Hilton, Karen Morris, Steven Seaman, Veera V. Shivaji R. Edupuganti, Kuo-Sheng Hsu, Christopher Dower, Guojun Yu, Daeho So, Pradip Bajgain, Zhongyu Zhu, Dimiter S. Dimitrov, Nimit L. Patel, Christina M. Robinson, Simone Difilippantonio, Marzena Dyba, Amanda Corbel, Falguni Basuli, Rolf E. Swenson, Joseph D. Kalen, Sreedhar Reddy Suthe, Myer Hussain, James S. Italia, Colby A. Souders, Ling Gao, Martin J. Schnermann, Brad St. Croix
Publikováno v:
Cell Reports, Vol 42, Iss 12, Pp 113503- (2023)
Summary: CD276/B7-H3 represents a promising target for cancer therapy based on widespread overexpression in both cancer cells and tumor-associated stroma. In previous preclinical studies, CD276 antibody-drug conjugates (ADCs) exploiting a talirine-ty
Externí odkaz:
https://doaj.org/article/01cdeaeafb064caf9db89ad85217f450
Autor:
Zehua Sun, Xiaojie Chu, Cynthia Adams, Tatiana V. Ilina, Michel Guerrero, Guowu Lin, Chuan Chen, Dontcho Jelev, Rieko Ishima, Wei Li, John W. Mellors, Guillermo Calero, Dimiter S. Dimitrov
Publikováno v:
Molecular Therapy: Oncolytics, Vol 31, Iss , Pp 100726- (2023)
Mesothelin (MSLN) has been a validated tumor-associated antigen target for several solid tumors for over a decade, making it an attractive option for therapeutic interventions. Novel antibodies with high affinity and better therapeutic properties are
Externí odkaz:
https://doaj.org/article/e3ac5eca01cc47a6b9a22161f0b5c4b7
Autor:
Chuan Chen, Zehua Sun, Zening Wang, Seungmin Shin, Abigail Berrios, John W. Mellors, Dimiter S. Dimitrov, Wei Li
Publikováno v:
Antibodies, Vol 13, Iss 2, p 39 (2024)
The anaplastic lymphoma kinase (ALK, CD247) is a potential target for antibody-based therapy. However, no antibody-based therapeutics targeting ALK have entered clinical trials, necessitating the development of novel antibodies with unique therapeuti
Externí odkaz:
https://doaj.org/article/1841d17e6802452dac45208d88414a5b
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
The high expression of uPAR has been linked to tumor progression, invasion, and metastasis in several types of cancer. Such overexpression of uPAR makes it a potential target for immunotherapies across common cancers such as breast, colorectal, lung,
Externí odkaz:
https://doaj.org/article/125c75797b304e3b90966c066708f5ad