Zobrazeno 1 - 10
of 226
pro vyhledávání: '"A S, Bommarius"'
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 10 (2022)
Pharmaceutical production quality has recently been a focus for improvement through incorporation of end-to-end continuous processing. Enzymatic ß-lactam antibiotic synthesis has been one focus for continuous manufacturing, and α-amino ester hydrol
Externí odkaz:
https://doaj.org/article/ce436edc9f4b45b6a82a2194566d69e8
Autor:
Simone Lauterbach, Hannah Dienhart, Jan Range, Stephan Malzacher, Jan-Dirk Spöring, Dörte Rother, Maria Filipa Pinto, Pedro Martins, Colton E. Lagerman, Andreas S. Bommarius, Amalie Vang Høst, John M. Woodley, Sandile Ngubane, Tukayi Kudanga, Frank T. Bergmann, Johann M. Rohwer, Dorothea Iglezakis, Andreas Weidemann, Ulrike Wittig, Carsten Kettner, Neil Swainston, Santiago Schnell, Jürgen Pleiss
Publikováno v:
Nature Methods. 20:400-402
Autor:
Laura L. Silva, Michael J. Stellato, Mariana V. Rodrigues, Bryan J. Hare, Jeffrey C. Kenvin, Andreas S. Bommarius, Leandro Martins, Carsten Sievers
Publikováno v:
Journal of Catalysis. 411:187-192
Autor:
Dalton C. Yu, Andreas S. Bommarius, Ronald W. Rousseau, Martha A. Grover, Patrick R. Harris, Hossein Salami
Publikováno v:
Chemical Engineering Research and Design. 177:473-483
Combining the synthesis and crystallization of a compound into a single step may be beneficial for certain processes. Motivations range from process intensification to improving reaction network yield by shifting an equilibrium limited reaction or pr
Autor:
Colton E. Lagerman, Janna K. Blum, Thomas A. Rogers, Martha A. Grover, Ronald W. Rousseau, Andreas S. Bommarius
Publikováno v:
Chemical Engineering Science. 277:118804
Autor:
Ronald W. Rousseau, Andreas S. Bommarius, Hossein Salami, Matthew A. McDonald, Martha A. Grover
Publikováno v:
Organic Process Research & Development. 25:1670-1679
Publikováno v:
Biotechnology and bioengineeringREFERENCES. 119(11)
The kinetics of cephalexin synthesis and hydrolysis of the activated acyl-donor precursor phenylglycine methyl ester (PGME) were characterized under a broad range of substrate concentrations. A previously developed model by Youshko-Svedas involving t
Autor:
Matthew A. McDonald, Andreas S. Bommarius, Sven Holger Behrens, Aditi Sharma, Harrison B. Rose, Yury O. Chernoff
Publikováno v:
The Journal of Physical Chemistry B. 125:4955-4963
Understanding the aggregation mechanism of amyloid proteins, such as Sup35NM, is essential to understanding amyloid diseases. Significant recent work has focused on using the fluorescence of thioflavin T (ThT), which undergoes a red shift when bound
Autor:
Marta C. Hatzell, Megan A. Kelly, Jasmine L. Ramirez, Carsten Sievers, Jason X. Kang, Jimin Park, Siddarth S. Seemakurti, Andreas S. Bommarius
Publikováno v:
Green Chemistry. 23:7488-7498
Active pharmaceutical ingredients (APIs) constitute a significant and growing global market. In the past few decades, labor costs, concerns regarding chemical waste, and more stringent regulations in developed countries have shifted the production of
Autor:
Patrick R. Harris, Hossein Salami, Colton E. Lagerman, Andreas S. Bommarius, Martha A. Grover, Xiaochuan Yang, Matthew A. McDonald, Ronald W. Rousseau
Publikováno v:
Reaction Chemistry & Engineering. 6:364-400
Reactive crystallization is not new, but there has been recent growth in its use as a means of improving performance and sustainability of industrial processes. This review examines phenomena and processes in which reaction and crystallization are co