Zobrazeno 1 - 10
of 215
pro vyhledávání: '"A Richard, Kitching"'
Autor:
Joshua D. Ooi, Jhih-Hang Jiang, Peter J. Eggenhuizen, Ling L. Chua, Mirjan van Timmeren, Khai L. Loh, Kim M. O’Sullivan, Poh Y. Gan, Yong Zhong, Kirill Tsyganov, Lani R. Shochet, Jessica Ryan, Coen A. Stegeman, Lars Fugger, Hugh H. Reid, Jamie Rossjohn, Peter Heeringa, Stephen R. Holdsworth, Anton Y. Peleg, A. Richard Kitching
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-14 (2019)
Autoreactivity to myeloperoxidase (MPO) causes autoimmune vasculitis and severe glomerulonephritis. Here, Ooi et al. show that a Staphylococcus aureus plasmid encodes a peptide that is homologous to an immunodominant MPO epitope and induces anti-MPO
Externí odkaz:
https://doaj.org/article/ec5422e66a47466790d6d136a48ebe74
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Anti-neutrophil cytoplasmic antibody (ANCA) associated vasculitis (AAV) is a rare and severe autoimmune multisystemic disease. Its pathogenesis involves multiple arms of the immune system, as well as complex interactions between immune cells and targ
Externí odkaz:
https://doaj.org/article/c23ab9ad09c14ae89b1195fea3dd9ceb
Autor:
Clare L. V. Westhorpe, M. Ursula Norman, Pam Hall, Sarah L. Snelgrove, Michaela Finsterbusch, Anqi Li, Camden Lo, Zhe Hao Tan, Songhui Li, Susan K. Nilsson, A. Richard Kitching, Michael J. Hickey
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-14 (2018)
Monocytes constitutively adhere and crawl along the glomerular endothelium and are thought to contribute to glomerulonephritis. Here the authors use multiphoton microscopy to show local antigen presentation by MHCII+ monocytes to T cells in glomerula
Externí odkaz:
https://doaj.org/article/22e1efaabd3040d59c9272c8e00fd9af
Autor:
Sarah L Snelgrove, Olivia Susanto, Louisa Yeung, Pamela Hall, M Ursula Norman, Alexandra J Corbett, A Richard Kitching, Michael J Hickey
Publikováno v:
Immunology & Cell Biology. 101:49-64
Autor:
Paul E. Gray, Hugh McCarthy, Owen M. Siggs, Moin A. Saleem, Tracy O' Brien, Katie Frith, John B. Ziegler, A. Richard Kitching, Agnes B. Fogo, Billy G. Hudson, Vadim Pedchenko
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Background: Goodpasture's disease (GP) is mediated by autoantibodies that bind the glomerular and alveolar basement membrane, causing rapidly progressive glomerulonephritis with or without pulmonary hemorrhage. The autoantibodies bind neoepitopes for
Externí odkaz:
https://doaj.org/article/a59d80731a224833ac98015c5a2fc9ab
Publikováno v:
Nephrology Dialysis Transplantation.
Glomerulonephritis (GN) is a diverse group of immune-mediated disorders. Currently, GN is classified largely by histological patterns that are difficult to understand and teach and most importantly, do not indicate treatment choices. Indeed, altered
Autor:
Ajinkya Bhonsle, Tim Coughlan, Rachel Graven, Paula Bussa, Michael Gingold, Kevan Polkinghorne, Jessica Ryan, A Richard Kitching
Publikováno v:
Rheumatology. 62
Background/Aims Patients with anti-neutrophil cytoplasmic antibody associated vasculitis (AAV) often have reduced health-related quality of life (HRQoL) as assessed by the SF-36 questionnaire. Global assessment provides a patient and physician’s vi
Autor:
Masaomi Nangaku, A. Richard Kitching, Peter Boor, Alessia Fornoni, Jürgen Floege, P. Toby Coates, Jonathan Himmelfarb, Rachel Lennon, Hans-Joachim Anders, Benjamin D. Humphreys, Fergus J. Caskey, Agnes B. Fogo, Andrea Angeletti, Patricia W. Bedard, Ariela Benigni, Anna Björnson Granqvist, Vera Certikova Chabova, Christos Chatziantoniou, Jennifer Cross, Sandrine Damster, Jo-Ann Donner, Frank Eitner, Stanislas Faguer, Antonio Fontanella, Yuri Fujimoto, Joseph Gaut, Leslie Gewin, Pernille B.L. Hansen, John Cijiang He, Jeremy Hughes, Reiko Inagi, Celia Jenkinson, Vivekanand Jha, Mikio Kato, Darren Kelly, Jeffrey Kopp, Ron Korstanje, Romaldas Mačiulaitis, Patrick B. Mark, Hans-Peter Marti, Stephen P. McAdoo, Jeffrey H. Miner, Alberto Ortiz, Samir M. Parikh, Ambra Pozzi, Paola Romagnani, Pierre Ronco, Brad H. Rovin, Julio Saez-Rodriguez, Moin A. Saleem, John A. Sayer, Stuart Shankland, Andrey S. Shaw, Yusuke Suzuki, Tomoko Takano, Sydney Tang, Rene Tolba, John Viel, Yoshihisa Yamada, Motoko Yanagita, Takashi Yokoo, Nobuya Yoshida, Darren Yuen, Roy Zent, Aihua Zhang
Publikováno v:
Kidney International.
Autor:
Olinski, Lauren, Wisheart, Danielle, Oka, Daisuke, Perreault, Lisa, Ramakrishnan, Boopathy, Richard Kitching, A., Babcock, Gregory, Shriver, Zachary, Viswanathan, Karthik
Publikováno v:
In Immunobiology September 2023 228(5)
Autor:
A. Richard Kitching, Lani Shochet
Publikováno v:
Current Opinion in Rheumatology. 34:10-17
PURPOSE OF REVIEW Vasculitis describes a wide spectrum of rare, inflammatory, multisystem disorders. These heterogenous diseases all have inflammation of blood vessels as a central feature. However, they differ in terms of their genetic and environme