Persistent inflammation and endothelial dysfunction in patients with treated acromegaly

Autor: T L C Wolters, C D C C van der Heijden, N van Leeuwen, B T P Hijmans-Kersten, M G Netea, J W A Smit, D H J Thijssen, A R M M Hermus, N P Riksen, R T Netea-Maier

Publikováno v: Endocrine Connections, Vol 8, Iss 12, Pp 1553-1567 (2019)

Objective: Acromegaly is characterized by an excess of growth hormone (GH) and insulin-like growth factor 1 (IGF1). Cardiovascular disease (CVD) risk factors are common in acromegaly and often persist after treatment. Both acute and long-lasting pro-

Externí odkaz: https://doaj.org/article/cee77be78a1f49389b248fc341f78de2

Conditioning cortisol in humans: design and pilot study of a randomized controlled trial

Autor: J. Tekampe, H. van Middendorp, F. C. G. J. Sweep, S. H. P. P. Roerink, A. R. M. M. Hermus, A. W. M. Evers

Publikováno v: Pilot and Feasibility Studies, Vol 5, Iss 1, Pp 1-10 (2019)

Abstract Background Conditioning of physiological responses can be achieved by repeatedly pairing a previously neutral conditioned stimulus with the administration of a pharmacologically salient unconditioned stimulus. This type of conditioning has b

Externí odkaz: https://doaj.org/article/678b710f11424630ad91bd21ef6093d8

Eight‐week exercise training in humans with obesity: Marked improvements in insulin sensitivity and modest changes in gut microbiome

Autor: Hauke Smidt, Prokopis Konstanti, Ad R. M. M. Hermus, Dick H. J. Thijssen, Rebecca J. H. M. Verheggen, Maria T. E. Hopman

Publikováno v: Obesity, 29, 10, pp. 1615-1624
Obesity, 29(10), 1615-1624
Obesity 29 (2021) 10
Obesity, 29, 1615-1624

Contains fulltext : 237734.pdf (Publisher’s version ) (Open Access) OBJECTIVE: Obesity is associated with impaired gut microbiota diversity, which has been linked to the development of type 2 diabetes. This study aims to examine the effects of an 8

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fe1d3fee3f9f097fa2f69f221bb32fb5
https://doi.org/10.1002/oby.23252

A disease-specific Quality of Life questionnaire for primary aldosteronism

Autor: Aline H. de Nooijer, Henri J L M Timmers, Marieke Velema, Jacques W.M. Lenders, Olga Husson, Ad R. M. M. Hermus, Jaap Deinum

Publikováno v: Endocrine Connections, Vol 8, Iss 4, Pp 389-397 (2019)
Endocrine Connections, 8, 4, pp. 389-397
Endocrine Connections, 8, 389-397
Endocrine Connections

Objective To develop a primary aldosteronism (PA) disease-specific Health-Related Quality of Life (HRQoL) questionnaire. Methods We included newly diagnosed patients with PA (n = 26), and patients with PA after adrenalectomy (n = 25) or treated with

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed3b7eb84f3e904f8222040630656641
https://ec.bioscientifica.com/view/journals/ec/8/4/EC-19-0026.xml

Cytokine responses to repeated, prolonged walking in lean versus overweight/obese individuals

Autor: Maria T. E. Hopman, Thijs M. H. Eijsvogels, Rob Ramakers, Coen C. W. G. Bongers, Rebecca J. H. M. Verheggen, Dick H. J. Thijssen, Marco Mensink, Rieneke Terink, Ad R. M. M. Hermus, Milène Catoire

Publikováno v: 2, 22, 196-200
Journal of Science and Medicine in Sport, 22, 2, pp. 196-200
Journal of Science and Medicine in Sport, 22, 196-200
Journal of Science and Medicine in Sport 22 (2019) 2
Journal of Science and Medicine in Sport, 22(2), 196-200

Item does not contain fulltext OBJECTIVES: Obesity is characterized by a pro-inflammatory state, which plays a role in the pathogenesis of metabolic and cardiovascular disease. An exercise bout causes a transient increase in pro-inflammatory cytokine

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6de6074336c68c31c1953fb9114db2a5
https://doi.org/10.1016/j.jsams.2018.07.019