Zobrazeno 1 - 10
of 320
pro vyhledávání: '"A R Grayson"'
Autor:
Hooriyah S. Rizavi, Omar S. Khan, Hui Zhang, Runa Bhaumik, Dennis R. Grayson, Ghanshyam N. Pandey
Publikováno v:
Translational Psychiatry, Vol 13, Iss 1, Pp 1-9 (2023)
Abstract A dysregulated hypothalamic-pituitary-adrenal (HPA) axis has repeatedly been demonstrated to play a fundamental role in psychiatric disorders and suicide, yet the mechanisms underlying this dysregulation are not clear. Decreased expression o
Externí odkaz:
https://doaj.org/article/1c4c58eb83d04267a50d23e25a747acf
Autor:
Wei-Yang Chen, Hu Chen, Kana Hamada, Eleonora Gatta, Ying Chen, Huaibo Zhang, Jenny Drnevich, Harish R. Krishnan, Mark Maienschein-Cline, Dennis R. Grayson, Subhash C. Pandey, Amy W. Lasek
Publikováno v:
Translational Psychiatry, Vol 11, Iss 1, Pp 1-12 (2021)
Abstract Alcohol use disorder (AUD) is highly comorbid with depression. Withdrawal from chronic alcohol drinking results in depression and understanding brain molecular mechanisms that drive withdrawal-related depression is important for finding new
Externí odkaz:
https://doaj.org/article/4f01af3adbe34d83bd69eca16d8ef2c2
Autor:
Henry Sershen, Alessandro Guidotti, James Auta, Jenny Drnevich, Dennis R. Grayson, Marin Veldic, Jordan Meyers, Mary Youseff, Adrian Zhubi, Keturah Faurot, Renrong Wu, Jingping Zhao, Hua Jin, Abel Lajtha, John M. Davis, Robert C. Smith
Publikováno v:
Biomarkers in Neuropsychiatry, Vol 5, Iss , Pp 100038- (2021)
Some of the biochemical abnormalities underlying schizophrenia, involve differences in methylation and methylating enzymes, as well as other related target genes. We present results of a study of differences in mRNA expression in peripheral blood lym
Externí odkaz:
https://doaj.org/article/0bbbabdd6f1d471e9a975af204f3de47
Akademický článek
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Autor:
Francesco, Matrisciano, Valentina, Locci, Erbo, Dong, Ferdinando, Nicoletti, Alessandro, Guidotti, Dennis R, Grayson
Publikováno v:
Current Neuropharmacology. 20:2354-2368
Background: mGlu5 metabotropic glutamate receptors are considered as candidate drug targets in the treatment of “monogenic” forms of autism spectrum disorders (ASD), such as Fragile- X syndrome (FXS). However, despite promising preclinical data,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2808b03a658690a18dd768714b2d3f8d
https://doi.org/10.2174/1567202619999220209112609
https://doi.org/10.2174/1567202619999220209112609
Autor:
Michael F. Rayo, Chelsea R. Horwood, Morgan C. Fitzgerald, Marisa R. Grayson, Mahmoud Abdel-Rasoul, Susan D. Moffatt-Bruce
Publikováno v:
IEEE Transactions on Human-Machine Systems. 52:984-993
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::eff9c2d6564c4684af4776835eb2bd89
https://doi.org/10.1109/thms.2022.3155714
https://doi.org/10.1109/thms.2022.3155714
Autor:
Peter M. Howley, Paola Dal Cin, Rajkumar Venkatramani, Songlin Zhang, Cristina R. Antonescu, Brian P. Rubin, Noam Grunfeld, Madeleine E. Lemieux, Adlai R. Grayson, Simone Kühnle, Erica M. Walsh, Shaila Rahman, Christopher A. French
PDF file - 171KB, Supplementary Fig. S2. NUT is translocated to the NSD3 locus in 1221 cell line as demonstrated by FISH on metaphase spread.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a50302a93f2cd6ca6b28c05bf26d71f
https://doi.org/10.1158/2159-8290.22529804
https://doi.org/10.1158/2159-8290.22529804
Autor:
Peter M. Howley, Paola Dal Cin, Rajkumar Venkatramani, Songlin Zhang, Cristina R. Antonescu, Brian P. Rubin, Noam Grunfeld, Madeleine E. Lemieux, Adlai R. Grayson, Simone Kühnle, Erica M. Walsh, Shaila Rahman, Christopher A. French
PDF file - 304KB, Supplementary Fig. S4. Among several ET-interacting proteins, only NSD3 is required for the blockade of differentiation in NMC. (A) Quantitative RT-PCR of NSD3, JMJD6, GLTSCR1, and ATAD5 levels 24 h following transfection of siRNAs.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d4dd5584e51e32f0fb10b4f995aa11a6
https://doi.org/10.1158/2159-8290.22529798.v1
https://doi.org/10.1158/2159-8290.22529798.v1
Autor:
David J. VanderWeele, Kathleen Kelly, Brian Capaldo, Jose Antonio Rodriguez-Nieves, Supreet Agarwal, Michael L. Beshiri, Keith H. Jansson, Wardah Bajwa, Adlai R. Grayson, Aian Neil Alilin, Yen Thi Minh Nguyen, Berkley E. Gryder, Remi Adelaiye-Ogala
The PI3K–AKT pathway has pleiotropic effects and its inhibition has long been of interest in the management of prostate cancer, where a compensatory increase in PI3K signaling has been reported following androgen receptor (AR) blockade. Prostate ca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a46cecee709ae33154b3f4813804f90
https://doi.org/10.1158/1535-7163.c.6542743
https://doi.org/10.1158/1535-7163.c.6542743
Autor:
Peter M. Howley, Paola Dal Cin, Rajkumar Venkatramani, Songlin Zhang, Cristina R. Antonescu, Brian P. Rubin, Noam Grunfeld, Madeleine E. Lemieux, Adlai R. Grayson, Simone Kühnle, Erica M. Walsh, Shaila Rahman, Christopher A. French
PDF file - 213KB, Supplementary Fig. S3. Wild type NSD3 is required for the blockade of differentiation in BRD4-NUT-expressing NMC cells, 8645 and PER-403.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e4a8c38d6ba83b5f728c14def70ff02
https://doi.org/10.1158/2159-8290.22529801.v1
https://doi.org/10.1158/2159-8290.22529801.v1