Zobrazeno 1 - 10
of 109
pro vyhledávání: '"A R, Simoneau"'
Autor:
Camille R. Simoneau, Pei-Yi Chen, Galen K. Xing, Jennifer M. Hayashi, Irene P. Chen, Mir M. Khalid, Nathan L. Meyers, Taha Y. Taha, Kristoffer E. Leon, Rahul K. Suryawanshi, Maria McCavitt-Malvido, Tal Ashuach, Krystal A. Fontaine, Lauren Rodriguez, Bastian Joehnk, Keith Walcott, Sreelakshmi Vasudevan, Xiaohui Fang, Mazharul Maishan, Shawn Schultz, Jeroen P. Roose, Michael A. Matthay, Anita Sil, Mehrdad Arjomandi, Nir Yosef, Melanie Ott
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-14 (2024)
Abstract As SARS-CoV-2 continues to spread worldwide, tractable primary airway cell models that recapitulate the cell-intrinsic response to arising viral variants are needed. Here we describe an adult stem cell-derived human airway organoid model ove
Externí odkaz:
https://doaj.org/article/2b9300e935d0405aa6dbdcaf44fa0f99
Autor:
Nathan L. Meyers, Tal Ashuach, Danielle E. Lyons, Mir M. Khalid, Camille R. Simoneau, Ann L. Erickson, Mehdi Bouhaddou, Thong T. Nguyen, G. Renuka Kumar, Taha Y. Taha, Vaishaali Natarajan, Jody L. Baron, Norma Neff, Fabio Zanini, Tokameh Mahmoudi, Stephen R. Quake, Nevan J. Krogan, Stewart Cooper, Todd C. McDevitt, Nir Yosef, Melanie Ott
Publikováno v:
mBio, Vol 14, Iss 6 (2023)
ABSTRACTHepatitis C virus (HCV) is the leading cause of death from liver disease. How HCV infection causes lasting liver damage and increases cancer risk remains unclear. Here, we identify bipotent liver stem cells as novel targets for HCV infection,
Externí odkaz:
https://doaj.org/article/f695e534948b44848663e858cae4c61b
Autor:
Kristoffer E Leon, Mir M Khalid, Ryan A Flynn, Krystal A Fontaine, Thong T Nguyen, G Renuka Kumar, Camille R Simoneau, Sakshi Tomar, David Jimenez-Morales, Mariah Dunlap, Julia Kaye, Priya S Shah, Steven Finkbeiner, Nevan J Krogan, Carolyn Bertozzi, Jan E Carette, Melanie Ott
Publikováno v:
PLoS Pathogens, Vol 19, Iss 1, p e1011070 (2023)
Zika virus (ZIKV) infects fetal neural progenitor cells (NPCs) causing severe neurodevelopmental disorders in utero. Multiple pathways involved in normal brain development are dysfunctional in infected NPCs but how ZIKV centrally reprograms these pat
Externí odkaz:
https://doaj.org/article/0d1aead7ce6046199c47abc95df35a11
Autor:
Vaishaali Natarajan, Camille R. Simoneau, Ann L. Erickson, Nathan L. Meyers, Jody L. Baron, Stewart Cooper, Todd C. McDevitt, Melanie Ott
Publikováno v:
Open Biology, Vol 12, Iss 3 (2022)
Hepatitis C virus (HCV) remains a global public health challenge with an estimated 71 million people chronically infected, with surges in new cases and no effective vaccine. New methods are needed to study the human immune response to HCV since in vi
Externí odkaz:
https://doaj.org/article/78e457851ade49b89befa8fa99f0a24a
Publikováno v:
Pharmaceutics, Vol 14, Iss 3, p 496 (2022)
Non-muscle-invasive bladder cancer (NMIBC) has one of the highest recurrence rates among all solid cancers and the highest lifetime treatment cost per patient. Therefore, the development of chemoprevention strategies for reducing the occurrence and r
Externí odkaz:
https://doaj.org/article/0b4040b01e9045f58a54ab7098751bc0
Autor:
Louise E. Hogan, Christian Körner, Kristen Hobbs, Camille R. Simoneau, Cassandra Thanh, Erica A. Gibson, Christine D. Palmer, Alisha Pandit, Francisco M. Marty, Daniel R. Kuritzkes, Stephanie Jost, Jerome Ritz, Timothy J. Henrich
Publikováno v:
Blood Advances, Vol 2, Iss 12, Pp 1412-1416 (2018)
Externí odkaz:
https://doaj.org/article/3c78a9f8587040878048911813098779
Perspective on this Article from Effects of the Kava Chalcone Flavokawain A Differ in Bladder Cancer Cells with Wild-type versus Mutant p53
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::73197499cf0e733d931bf411f451b66b
https://doi.org/10.1158/1940-6207.22523449.v1
https://doi.org/10.1158/1940-6207.22523449.v1
PDF file - 63K, The majority of female UPII-SV40T mice survive beyond 318 days of age, and There is no significant difference in average food consumpation between vehicle control and FKA treatment groups.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::64569d46c0761fbd9e6f9768358a9421
https://doi.org/10.1158/1940-6207.22524197.v1
https://doi.org/10.1158/1940-6207.22524197.v1
Supplementary Figures S1 and S2 from Effects of the Kava Chalcone Flavokawain A Differ in Bladder Cancer Cells with Wild-type versus Mutant p53
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48a11f35df2e6e1158d9808369ef2ee6
https://doi.org/10.1158/1940-6207.22523446.v1
https://doi.org/10.1158/1940-6207.22523446.v1
Autor:
Rahul K. Suryawanshi, Irene P. Chen, Tongcui Ma, Abdullah M. Syed, Noah Brazer, Prachi Saldhi, Camille R. Simoneau, Alison Ciling, Mir M. Khalid, Bharath Sreekumar, Pei-Yi Chen, G. Renuka Kumar, Mauricio Montano, Ronne Gascon, Chia-Lin Tsou, Miguel A. Garcia-Knight, Alicia Sotomayor-Gonzalez, Venice Servellita, Amelia Gliwa, Jenny Nguyen, Ines Silva, Bilal Milbes, Noah Kojima, Victoria Hess, Maria Shacreaw, Lauren Lopez, Matthew Brobeck, Fred Turner, Frank W. Soveg, Ashley F. George, Xiaohui Fang, Mazharul Maishan, Michael Matthay, Mary Kate Morris, Debra Wadford, Carl Hanson, Warner C. Greene, Raul Andino, Lee Spraggon, Nadia R. Roan, Charles Y. Chiu, Jennifer A. Doudna, Melanie Ott
Publikováno v:
Nature, vol 607, iss 7918
SARS-CoV-2 Delta and Omicron are globally relevant variants of concern. Although individuals infected with Delta are at risk of developing severe lung disease, infection with Omicron often causes milder symptoms, especially in vaccinated individuals1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a457aae7118cf5f209aea878cc86dd9
https://doi.org/10.1038/s41586-022-04865-0
https://doi.org/10.1038/s41586-022-04865-0