Zobrazeno 1 - 10
of 45
pro vyhledávání: '"A R, Mazloom"'
Autor:
Amin R. Mazloom, Huilei Xu, Jaume Reig-Palou, Ana Vasileva, Angel-Carlos Román, Sonia Mulero-Navarro, Ihor R. Lemischka, Ana Sevilla
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 10 (2022)
Characterization of pluripotent states, in which cells can both self-renew or differentiate, with the irreversible loss of pluripotency, are important research areas in developmental biology. Although microRNAs (miRNAs) have been shown to play a rele
Externí odkaz:
https://doaj.org/article/9157c4114685456a9a9eefd77bed681f
Autor:
Ana Sevilla, Dimitri Papatsenko, Amin R. Mazloom, Huilei Xu, Ana Vasileva, Richard D. Unwin, Gary LeRoy, Edward Y. Chen, Francine E. Garrett-Bakelman, Dung-Fang Lee, Benjamin Trinite, Ryan L. Webb, Zichen Wang, Jie Su, Julian Gingold, Ari Melnick, Benjamin A. Garcia, Anthony D. Whetton, Ben D. MacArthur, Avi Ma’ayan, Ihor R. Lemischka
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
Cell fate decisions during development are governed by multi-factorial regulatory mechanisms including chromatin remodeling, DNA methylation, binding of transcription factors to specific loci, RNA transcription and protein synthesis. However, the mec
Externí odkaz:
https://doaj.org/article/67b02d769bf444e29916c542735c28dd
Autor:
Razelle Kurzrock, Mathias Ehrich, Daniel S. Grosu, Graham McLennan, Amin R. Mazloom, Erin McCarthy, Prachi Nakashe, Lisa Kim, Gregory A. Daniels, Christopher K. Ellison, Shumei Kato, Aaron M. Goodman, Taylor J. Jensen
Supplementary Table 1. Patient clinical characteristics (N=44 patients). *PFS values with a (+) indicate response is ongoing at time of data censoring Abbreviations: cfDNA = cell-free DNA; CR = complete response; GE = gene equivalents per mL; GE junc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c6f6fe87d54e7b101f7d0bd5f70e485f
https://doi.org/10.1158/1535-7163.22507854.v1
https://doi.org/10.1158/1535-7163.22507854.v1
Autor:
Razelle Kurzrock, Mathias Ehrich, Daniel S. Grosu, Graham McLennan, Amin R. Mazloom, Erin McCarthy, Prachi Nakashe, Lisa Kim, Gregory A. Daniels, Christopher K. Ellison, Shumei Kato, Aaron M. Goodman, Taylor J. Jensen
Inhibitors of the PD-1/PD-L1/CTLA-4 immune checkpoint pathway have revolutionized cancer treatment. Indeed, some patients with advanced, refractory malignancies achieve durable responses; however, only a subset of patients benefit, necessitating new
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f10a1990e404d66946996eef099fec7
https://doi.org/10.1158/1535-7163.c.6538806
https://doi.org/10.1158/1535-7163.c.6538806
Autor:
Amin R. Mazloom, Mohammad Abbasi, Steven Lockton, Sharat Singh, Richard Del Mastro, Christopher Robinson, Michael J Paglia, Philip Uren, Jenna Hendershot, Pankaj Oberoi, Matthew Cooper
Background Preeclampsia is a common cause of maternal and neonatal mortality, and to date there is no definitive, diagnostic test available. We aimed to develop a test to detect preeclampsia using biomarkers representing different pathogenic pathways
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9529c965e5acf7a0e5534cb72505c3bb
https://doi.org/10.21203/rs.3.rs-2196679/v1
https://doi.org/10.21203/rs.3.rs-2196679/v1
Autor:
Jenna M. Hendershot, Mohammad Abbasi, Laura Fortier, Maleah Benn, Camille Giacobone, Richard Del Mastro, Emad Bahrami-Samani, Amin R. Mazloom, Pankaj Oberoi
Publikováno v:
Journal of pharmaceutical and biomedical analysis. 214
Preeclampsia is a serious condition responsible for much pregnancy-related morbidity and mortality. Diagnosis of preeclampsia is difficult due to the non-specific and subjective nature of symptoms of the disease. To reduce the subjective decision mak
Autor:
Amin R. Mazloom, Huilei Xu, Jaume Reig-Palou, Ana Vasileva, Angel-Carlos Román, Sonia Mulero-Navarro, Ihor R. Lemischka, Ana Sevilla
Publikováno v:
Frontiers in cell and developmental biology. 10
Characterization of pluripotent states, in which cells can both self-renew or differentiate, with the irreversible loss of pluripotency, are important research areas in developmental biology. Although microRNAs (miRNAs) have been shown to play a rele
Non-invasive prenatal chromosomal aneuploidy testing--clinical experience: 100,000 clinical samples.
Autor:
Ron M McCullough, Eyad A Almasri, Xiaojun Guan, Jennifer A Geis, Susan C Hicks, Amin R Mazloom, Cosmin Deciu, Paul Oeth, Allan T Bombard, Bill Paxton, Nilesh Dharajiya, Juan-Sebastian Saldivar
Publikováno v:
PLoS ONE, Vol 9, Iss 10, p e109173 (2014)
OBJECTIVE: As the first laboratory to offer massively parallel sequencing-based noninvasive prenatal testing (NIPT) for fetal aneuploidies, Sequenom Laboratories has been able to collect the largest clinical population experience data to date, includ
Externí odkaz:
https://doaj.org/article/111113173d1246f08e586fb0b3a90399
Autor:
Taylor J Jensen, Tricia Zwiefelhofer, Roger C Tim, Željko Džakula, Sung K Kim, Amin R Mazloom, Zhanyang Zhu, John Tynan, Tim Lu, Graham McLennan, Glenn E Palomaki, Jacob A Canick, Paul Oeth, Cosmin Deciu, Dirk van den Boom, Mathias Ehrich
Publikováno v:
PLoS ONE, Vol 8, Iss 3, p e57381 (2013)
Circulating cell-free (ccf) fetal DNA comprises 3-20% of all the cell-free DNA present in maternal plasma. Numerous research and clinical studies have described the analysis of ccf DNA using next generation sequencing for the detection of fetal aneup
Externí odkaz:
https://doaj.org/article/78d3d7087d2344168e14150bfa8beb58
Autor:
Amin R Mazloom, Ruth Dannenfelser, Neil R Clark, Arsen V Grigoryan, Kathryn M Linder, Timothy J Cardozo, Julia C Bond, Aislyn D W Boran, Ravi Iyengar, Anna Malovannaya, Rainer B Lanz, Avi Ma'ayan
Publikováno v:
PLoS Computational Biology, Vol 7, Iss 12, p e1002319 (2011)
Coregulator proteins (CoRegs) are part of multi-protein complexes that transiently assemble with transcription factors and chromatin modifiers to regulate gene expression. In this study we analyzed data from 3,290 immuno-precipitations (IP) followed
Externí odkaz:
https://doaj.org/article/0cee1b71d698463991acce0891a5005a