Zobrazeno 1 - 10
of 511
pro vyhledávání: '"A R, Masters"'
Autor:
Cynthia D. Jesudason, Emily R. Mason, Shaoyou Chu, Adrian L. Oblak, June Javens‐Wolfe, Mustapha Moussaif, Greg Durst, Philip Hipskind, Daniel E. Beck, Jiajun Dong, Ovini Amarasinghe, Zhong‐Yin Zhang, Adam K. Hamdani, Kratika Singhal, Andrew D. Mesecar, Sarah Souza, Marlene Jacobson, Jerry Di Salvo, Disha M. Soni, Murugesh Kandasamy, Andrea R. Masters, Sara K Quinney, Suzanne Doolen, Hasi Huhe, Stacey J. Sukoff Rizzo, Bruce T. Lamb, Alan D. Palkowitz, Timothy I. Richardson
Publikováno v:
Alzheimer’s & Dementia: Translational Research & Clinical Interventions, Vol 9, Iss 4, Pp n/a-n/a (2023)
Abstract INTRODUCTION The risk of developing Alzheimer's disease is associated with genes involved in microglial function. Inositol polyphosphate‐5‐phosphatase (INPP5D), which encodes Src homology 2 (SH2) domain–containing inositol polyphosphat
Externí odkaz:
https://doaj.org/article/4d6f6a10135b4cdbb5e5fc4dd51947a7
Autor:
Yana Vorontsova, David M. Haas, Kathleen Flannery, Andrea R. Masters, Larissa L. Silva, Rebecca C. Pierson, Brittany Yeley, Graham Hogg, David Guise, Michael Heathman, Sara K. Quinney
Publikováno v:
Clinical and Translational Science, Vol 15, Iss 8, Pp 1937-1945 (2022)
Abstract The IMPROVE study (NCT02408315) compared the efficacy and safety of vaginal and buccal administration of misoprostol for full‐term, uncomplicated labor induction. This report compares the pharmacokinetics of misoprostol between vaginal and
Externí odkaz:
https://doaj.org/article/7c50265f0c84462491bd4ebd26d02f28
Autor:
Blessed W. Aruldhas, Sara K. Quinney, Brian R. Overholser, Michael A. Heathman, Andrea R. Masters, Reynold C. Ly, Hongyu Gao, Senthil Packiasabapathy, Senthilkumar Sadhasivam
Publikováno v:
CPT: Pharmacometrics & Systems Pharmacology, Vol 10, Iss 10, Pp 1183-1194 (2021)
Abstract Methadone is a synthetic opioid used as an analgesic and for the treatment of opioid abuse disorder. The analgesic dose in the pediatric population is not well‐defined. The pharmacokinetics (PKs) of methadone is highly variable due to the
Externí odkaz:
https://doaj.org/article/a2dc0c6bf16a46479c6de8ed638d0c6b
Autor:
Adrian L. Oblak, Zackary A. Cope, Sara K. Quinney, Ravi S. Pandey, Carla Biesdorf, Andi R. Masters, Kristen D. Onos, Leslie Haynes, Kelly J. Keezer, Jill A. Meyer, Jonathan S. Peters, Scott A. Persohn, Amanda A. Bedwell, Kierra Eldridge, Rachael Speedy, Gabriela Little, Sean‐Paul Williams, Brenda Noarbe, Andre Obenaus, Michael Sasner, Gareth R. Howell, Gregory W. Carter, Harriet Williams, Bruce T. Lamb, Paul R. Territo, Stacey J. Sukoff Rizzo
Publikováno v:
Alzheimer’s & Dementia: Translational Research & Clinical Interventions, Vol 8, Iss 1, Pp n/a-n/a (2022)
Abstract Introduction Alzheimer's disease (AD) is the most common form of dementia. Beta‐secretase (BACE) inhibitors have been proposed as potential therapeutic interventions; however, initiating treatment once disease has significantly progressed
Externí odkaz:
https://doaj.org/article/049b9fdfe3964b8f8a93c11191a73a7d
Autor:
Kristen D. Onos, Sara K. Quinney, David R. Jones, Andrea R. Masters, Ravi Pandey, Kelly J. Keezer, Carla Biesdorf, Ingrid F. Metzger, Jill A. Meyers, Johnathon Peters, Scott C. Persohn, Brian P. McCarthy, Amanda A. Bedwell, Lucas L. Figueiredo, Zackary A. Cope, Michael Sasner, Gareth R. Howell, Harriet M. Williams, Adrian L. Oblak, Bruce T. Lamb, Gregory W. Carter, Stacey J. Sukoff Rizzo, Paul R. Territo
Publikováno v:
Alzheimer’s & Dementia: Translational Research & Clinical Interventions, Vol 8, Iss 1, Pp n/a-n/a (2022)
Abstract Introduction Hyperexcitability and epileptiform activity are commonplace in Alzheimer's disease (AD) patients and associated with impaired cognitive function. The anti‐seizure drug levetiracetam (LEV) is currently being evaluated in clinic
Externí odkaz:
https://doaj.org/article/6aac82fc377b4d76a3023ef60872d04a
Publikováno v:
Journal of Chemical Information and Modeling. 63:1695-1707
Autor:
Chandrali S. Bhattacharya, Andrea R. Masters, Christine Bach, Anthony L. Sinn, Melissa A. Trowbridge, Robert E. Stratford
Publikováno v:
European Journal of Drug Metabolism and Pharmacokinetics. 48:171-187
Autor:
Gregory G Grecco, Briana E Mork, Jui-Yen Huang, Corinne E Metzger, David L Haggerty, Kaitlin C Reeves, Yong Gao, Hunter Hoffman, Simon N Katner, Andrea R Masters, Cameron W Morris, Erin A Newell, Eric A Engleman, Anthony J Baucum, Jiuen Kim, Bryan K Yamamoto, Matthew R Allen, Yu-Chien Wu, Hui-Chen Lu, Patrick L Sheets, Brady K Atwood
Publikováno v:
eLife, Vol 10 (2021)
Despite the rising prevalence of methadone treatment in pregnant women with opioid use disorder, the effects of methadone on neurobehavioral development remain unclear. We developed a translational mouse model of prenatal methadone exposure (PME) tha
Externí odkaz:
https://doaj.org/article/5a76cf5be8ef4e9aa4a2a863c7ea3745
Autor:
Brandon T. Gufford, Ingrid F. Metzger, Nadia O. Bamfo, Eric A. Benson, Andrea R. Masters, Jessica Bo Li Lu, Zeruesenay Desta
Publikováno v:
Journal of Pharmacology and Experimental Therapeutics. 382:313-326