Zobrazeno 1 - 10
of 157
pro vyhledávání: '"A R, MONACO"'
Autor:
William R. Morgenlander, Wan Ni Chia, Beatriz Parra, Daniel R. Monaco, Izabela Ragan, Carlos A. Pardo, Richard Bowen, Diana Zhong, Douglas E. Norris, Ingo Ruczinski, Anna Durbin, Lin-Fa Wang, H. Benjamin Larman, Matthew L. Robinson
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-12 (2024)
Abstract Arthropod-borne viruses represent a crucial public health threat. Current arboviral serology assays are either labor intensive or incapable of distinguishing closely related viruses, and many zoonotic arboviruses that may transition to human
Externí odkaz:
https://doaj.org/article/d16881e0128e4a6db54144ff029cf0b7
Autor:
Daniel R. Monaco, Brandon M. Sie, Thomas R. Nirschl, Audrey C. Knight, Hugh A. Sampson, Anna Nowak-Wegrzyn, Robert A. Wood, Robert G. Hamilton, Pamela A. Frischmeyer-Guerrerio, H. Benjamin Larman
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-10 (2021)
A diverse array of antigens can trigger allergic reactions. Here the authors present the ‘AllerScan’ programmable phage display library, which is an efficient and unbiased approach for profiling anti-allergen antibody reactivities at cohort scale
Externí odkaz:
https://doaj.org/article/b8e61b941a1b437c95176c991f1acd7e
Autor:
Daniel R. Monaco, Sanjay V. Kottapalli, Florian P. Breitwieser, Danielle E. Anderson, Limin Wijaya, Kevin Tan, Wan Ni Chia, Kai Kammers, Patrizio Caturegli, Kathleen Waugh, Mario Roederer, Michelle Petri, Daniel W. Goldman, Marian Rewers, Lin-Fa Wang, H. Benjamin Larman
Publikováno v:
EBioMedicine, Vol 75, Iss , Pp 103747- (2022)
Summary: Background: Comprehensive characterization of exposures and immune responses to viral infections is critical to a basic understanding of human health and disease. We previously developed the VirScan system, a programmable phage-display techn
Externí odkaz:
https://doaj.org/article/2cc445a3d2704ef8b00c16df22299c39
Autor:
Gabriel D. Román-Meléndez, Daniel R. Monaco, Janelle M. Montagne, Rachel S. Quizon, Maximilian F. Konig, Mekbib Astatke, Erika Darrah, H. Benjamin Larman
Publikováno v:
EBioMedicine, Vol 71, Iss , Pp 103506- (2021)
Background: Post-translational modifications (PTMs) on proteins can be targeted by antibodies associated with autoimmunity. Despite a growing appreciation for their intrinsic role in disease, there is a lack of highly multiplexed serological assays t
Externí odkaz:
https://doaj.org/article/82af569aa0244ab8905c2ce7c8ac7508
Autor:
Kai Kammers, Athena Chen, Daniel R. Monaco, Sarah E. Hudelson, Wendy Grant-McAuley, Richard D. Moore, Galit Alter, Steven G. Deeks, Charles S. Morrison, Leigh A. Eller, Joel N. Blankson, Oliver Laeyendecker, Ingo Ruczinski, Susan H. Eshleman, H. Benjamin Larman
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
IntroductionLow HIV viral load is associated with delayed disease progression and reduced HIV transmission. HIV controllers suppress viral load to low levels in the absence of antiretroviral treatment (ART). We used an antibody profiling system, VirS
Externí odkaz:
https://doaj.org/article/e4d57189af8a484ba845d1a29bae07de
Autor:
Rachel M. Wise, Sara Al-Ghadban, Mark A. A. Harrison, Brianne N. Sullivan, Emily R. Monaco, Sarah J. Aleman, Umberto M. Donato, Bruce A. Bunnell
Publikováno v:
Cells, Vol 11, Iss 9, p 1376 (2022)
Human adipose-derived stem cells (hASCs) are potent modulators of inflammation and promising candidates for the treatment of inflammatory and autoimmune diseases. Strategies to improve hASC survival and immunoregulation are active areas of investigat
Externí odkaz:
https://doaj.org/article/59f60adad476491292818439fabdac2e
Autor:
Joel J. Credle, Jonathan Gunn, Puwanat Sangkhapreecha, Daniel R. Monaco, Xuwen Alice Zheng, Hung-Ji Tsai, Azaan Wilbon, William R. Morgenlander, Andre Rastegar, Yi Dong, Sahana Jayaraman, Lorenzo Tosi, Biju Parekkadan, Alan N. Baer, Mario Roederer, Evan M. Bloch, Aaron A. R. Tobian, Israel Zyskind, Jonathan I. Silverberg, Avi Z. Rosenberg, Andrea L. Cox, Tom Lloyd, Andrew L. Mammen, H. Benjamin Larman
Publikováno v:
Nat Biomed Eng
Pathogenic autoreactive antibodies that may be associated with life-threatening Coronavirus disease 2019 (COVID-19) remain to be identified. Here we show that self-assembled genome-scale libraries of full-length proteins covalently coupled to unique
Autor:
Susan H. Eshleman, Oliver Laeyendecker, Kai Kammers, Athena Chen, Mariya V. Sivay, Sanjay Kottapalli, Brandon M. Sie, Tiezheng Yuan, Daniel R. Monaco, Divya Mohan, Daniel Wansley, Tomasz Kula, Charles Morrison, Stephen J. Elledge, Ron Brookmeyer, Ingo Ruczinski, H. Benjamin Larman
Publikováno v:
Cell Reports, Vol 27, Iss 5, Pp 1422-1433.e4 (2019)
Summary: This study evaluates HIV antibody responses and their evolution during the course of HIV infection. A phage display system is used to characterize antibody binding to >3,300 HIV peptides in 57 adults with early- to late-stage infection. We f
Externí odkaz:
https://doaj.org/article/8c14e7e5d4564c0c94e406008899f3db
Autor:
Rachel M. Wise, Mark A. A. Harrison, Brianne N. Sullivan, Sara Al-Ghadban, Sarah J. Aleman, Amber T. Vinluan, Emily R. Monaco, Umberto M. Donato, India A. Pursell, Bruce A. Bunnell
Publikováno v:
Cells, Vol 9, Iss 10, p 2218 (2020)
Human adipose-derived stem cells (ASCs) show immense promise for treating inflammatory diseases, attributed primarily to their potent paracrine signaling. Previous investigations demonstrated that short-term Rapamycin preconditioning of bone marrow-d
Externí odkaz:
https://doaj.org/article/53527e44eca64861bedf6b667e8a2aa7
Autor:
Pamela A. Frischmeyer-Guerrerio, Anna Nowak-Wegrzyn, Audrey C. Knight, Daniel R. Monaco, Thomas R. Nirschl, Brandon M. Sie, Robert A. Wood, H. Benjamin Larman, Robert G. Hamilton, Hugh A. Sampson
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-10 (2021)
Nature Communications
Nature Communications
Allergic reactions occur when IgE molecules become crosslinked by antigens such as food proteins. Here we create the ‘AllerScan’ programmable phage display system to characterize the binding specificities of anti-allergen IgG and IgE antibodies i