Zobrazeno 1 - 10
of 22
pro vyhledávání: '"A R, Kuchumov"'
Autor:
Anton V. Malyshev, Iuliia A. Sukhanova, Alexander S. Zlobin, Vasilina R. Gedzun, Vsevolod V. Pavshintsev, Ekaterina V. Vasileva, Arthur O. Zalevsky, Igor I. Doronin, Nikita A. Mitkin, Andrey V. Golovin, Maxim L. Lovat, Georgy I. Kovalev, Yurii A. Zolotarev, Askar R. Kuchumov, Gennady A. Babkin, Bernhard Luscher
Publikováno v:
Frontiers in Neuroscience, Vol 15 (2021)
The aim of the study was to develop better anxiolytics and antidepressants. We focused on GABAA receptors and the α2δ auxiliary subunit of V-gated Ca2+ channels as putative targets because they are established as mediators of efficacious anxiolytic
Externí odkaz:
https://doaj.org/article/744533a44c374b5489533f40fc433b89
Autor:
V. Korkhov, R. Kuchumov
Publikováno v:
9th International Conference "Distributed Computing and Grid Technologies in Science and Education".
The goal of this research work is to reduce wait time of HPC (high performance computing) applications in schedulers queue by applying a co-scheduling strategy. This strategy allows the execution of more than one task with different non-overlapping r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3ae59f24eeba78ac934ba502eac047cd
https://doi.org/10.54546/mlit.2021.21.34.001
https://doi.org/10.54546/mlit.2021.21.34.001
Publikováno v:
Journal of Protein Chemistry. 19:139-149
The giant, approximately 3.6-MDa hexagonal bilayer hemoglobin (Hb) of Lumbricus terrestris consist of twelve 213-kDa globin subassemblies, each comprised of three disulfide-bonded trimers and three monomer globin chains, tethered to a central scaffol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0641281bd4cc63257ef21c8b0fb42e99
https://doi.org/10.1023/a:1007086717412
https://doi.org/10.1023/a:1007086717412
Autor:
Jean-Christophe Taveau, Roy E. Weber, Joseph S. Wall, Jean N. Lamy, Askar R. Kuchumov, Serge N. Vinogradov
Publikováno v:
Journal of Molecular Biology. 289:1361-1374
The extent and kinetics of reassembly of the four groups of linkers L1-L4 with 213 kDa subassemblies of twelve globin chains D, (bac)3(d)3, isolated from the approximately 3.6 MDa hexagonal bilayer (HBL) hemoglobin (Hb) of Lumbricus terrestris, was i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e440f188af0cccc67d6b92bcc031d60e
https://doi.org/10.1006/jmbi.1999.2825
https://doi.org/10.1006/jmbi.1999.2825
Publikováno v:
International Journal of Mass Spectrometry. 188:105-112
The complex, multiply charged electrospray ionization mass spectra of the extracellular, ∼3500 kDa, hexagonal bilayer hemoglobin from the leech Haemopis grandis and its carbamidomethylated, reduced and reduced/carbamidomethylated forms were deconvo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1c9283a96106f0b4ffdefc76547e2656
https://doi.org/10.1016/s1387-3806(98)14285-9
https://doi.org/10.1016/s1387-3806(98)14285-9
Publikováno v:
Biophysical Chemistry. 77:27-35
The giant approximately 3.6 MDa hexagonal bilayer hemoglobin (HBL Hb) from Lumbricus terrestris consists of 12 213-kDa dodecamers of four globin chains ([b + a + c]3[d]3) tethered to a central scaffold of approximately 36 non-globin, linker subunits
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e5786197d686992a212ebb221beb6c3
https://doi.org/10.1016/s0301-4622(99)00006-x
https://doi.org/10.1016/s0301-4622(99)00006-x
Publikováno v:
Biochemistry
The quaternary structure of the cysteine-rich, approximately 3500-kDa chlorocruorin (Chl) from the marine polychaete Eudistylia vancouverii was investigated using maximum entropy deconvolution of the electrospray ionization mass spectra (ESIMS). The
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1594aeae959f81780ac5edc7cb4c00b1
https://doi.org/10.1021/bi972644y
https://doi.org/10.1021/bi972644y
Autor:
Serge N. Vinogradov, Askar R. Kuchumov, Roy E. Weber, Geneviève Chottard, Pawan K. Sharma, Peter Zipper, Angelica Krebs, Emory H. Braswell
Publikováno v:
Journal of Biological Chemistry. 271:18695-18704
Small angle x-ray scattering of the 213-kDa dodecamer of Lumbricus terrestris Hb yielded radius of gyration = 3.74 +/- 0.01 nm, maximum diameter = 10.59 +/- 0.01 nm, and volume = 255 +/- 10 nm3, with no difference between the oxy and deoxy states. Se
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df60746ec8f2a0ec908ec1fdad2535c9
https://doi.org/10.1074/jbc.271.31.18695
https://doi.org/10.1074/jbc.271.31.18695
Publikováno v:
Archives of Biochemistry and Biophysics. 330:281-284
The giant hemoglobin, which occurs in free solution in the blood of earthworms, contains copper and zinc and exhibits superoxide dismutase activity as assessed by competition assays using cytochrome c or nitroblue tetrazolium. On a molar basis, the a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1be26d19ceed2e785b5025451f910798
https://doi.org/10.1006/abbi.1996.0254
https://doi.org/10.1006/abbi.1996.0254
Autor:
Philip D. Martin, Joseph S. Wall, Serge N. Vinogradov, Askar R. Kuchumov, Geneviève Chottard, Pawan K. Sharma
Publikováno v:
Journal of Biological Chemistry. 271:8754-8762
The dissociation of the approximately 3500-kDa hexagonal bilayer (HBL) hemoglobin (Hb) of Lumbricus terrestris upon exposure to Gdm salts, urea and the heteropolytungstates [SiW11O39]8- (SiW), [NaSb9W21O86]18- (SbW) and [BaAs4W40O140]27- (AsW) at neu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::44f56ce0d40b665dd5ff87bba9168448
https://doi.org/10.1074/jbc.271.15.8754
https://doi.org/10.1074/jbc.271.15.8754