Zobrazeno 1 - 10
of 111
pro vyhledávání: '"A Pyesmany"'
Autor:
Seibel, Nita L., Steinherz, Peter G., Sather, Harland N., Nachman, James B., DeLaat, Cynthia, Ettinger, Lawrence J., Freyer, David R., Mattano, Leonard A., Jr, Hastings, Caroline A., Rubin, Charles M., Bertolone, Kathy, Franklin, Janet L., Heerema, Nyla A., Mitchell, Torrey L., Pyesmany, Allan F., La, Mei K., Edens, Cheryl, Gaynon, Paul S.
Publikováno v:
In Blood 1 March 2008 111(5):2548-2555
Publikováno v:
Tissue Antigens. 16:70-72
HLA antigens of the A and B loci were determined on the lymphocytes of 30 patients with acute lymphocytic leukemia (A.L.L.), as well as all of their mothers and 26 of the fathers. Seven of the 26 parents shared a common haplotype. This incidence of 2
Publikováno v:
Medical and Pediatric Oncology. 28:65-68
We report a case of congenital retroperitoneal fibrosarcoma presenting in a 17-day-old male in which surgical tumor debulking was followed by chemotherapy. His clinical course was complicated. Intraoperatively, 80% of the tumor was removed and he exp
Autor:
Neil J. Grossman, W A Bleyer, Gregory H. Reaman, A R Ablin, Louis Novak, Allan F. Pyesmany, Paul S. Gaynon, J Z Finklestein, V C Albo, Peter G. Steinherz
Publikováno v:
Journal of Clinical Oncology. 11:2234-2242
PURPOSE On past Childrens Cancer Group (CCG) trials, children with acute lymphoblastic leukemia and unfavorable presenting features had obtained an event-free survival (EFS) rate of no better than 50%. Following promising pilot experience, this study
Autor:
G. Denman Hammond, Linda P. Miller, Allan F. Pyesmany, Paul Rogers, Stuart E. Siegel, Robert J. Wells, Lawrence J. Wolff, Jonathan D. Buckley
Publikováno v:
Cancer. 67:2235-2240
Amsacrine (AMSA) and cyclocytidine were studied as retrieval therapy in 122 pediatric patients with acute nonlymphoblastic leukemia (ANLL). Patients either failed to achieve sustained initial remissions or were in relapse. Induction therapy consisted
Autor:
Torrey L. Mitchell, Janet Franklin, Peter G. Steinherz, Nyla A. Heerema, Leonard A. Mattano, Caroline Hastings, Mei K. La, Cheryl Edens, Kathy Bertolone, Cynthia DeLaat, Lawrence J. Ettinger, Nita L. Seibel, Harland Sather, James B. Nachman, Charles M. Rubin, Paul S. Gaynon, Allan F. Pyesmany, David R. Freyer
Publikováno v:
Blood. 111(5)
Longer and more intensive postinduction intensification (PII) improved the outcome of children and adolescents with “higher risk” acute lymphoblastic leukemia (ALL) and a slow marrow response to induction therapy. In the Children's Cancer Group s
Publikováno v:
Advances in experimental medicine and biology. 457
New analogues of DNA directed chemotherapy moieties are available for comparative efficacy testing in human neoplastic disease. In addition to MTT testing direct assessment of DNA excision repair activity after direct exposure of marrow cells may pro
Publikováno v:
Advances in experimental medicine and biology. 457
Genomic instability may, especially with DNA directed treatment, be associated with increased therapeutic response; absence may be associated with drug resistance. In childhood MNHL, drug response is variable. At present the degree of presence of mic
Autor:
L M, Ball, C L, Lannon, M, Yhap, A F, Pyesmany, M, Henry, K, Laybolt, D C, Riddell, D, van Velzen
Publikováno v:
Advances in experimental medicine and biology. 457
Drug resistance to DNA directed therapy may depend on proliferative as well as apoptotic cell fraction. PCNA/Ki67 ratio excess, possibly reflecting DNA excision repair, is of additional interest to drug resistance in MTT testing. The cell cycle phase
Publikováno v:
Advances in experimental medicine and biology. 457
Apoptotic cell fraction and presence or degree of aneuploidy may both affect treatment outcome in childhood acute lymphoblastic leukaemia (ALL), which is largely defined by drug resistance. Independence of the variables is at present not established.