Increased AID results in mutations at the CRLF2 locus implicated in Latin American ALL health disparities

Autor: Valeria Rangel, Jason N. Sterrenberg, Aya Garawi, Vyanka Mezcord, Melissa L. Folkerts, Sabrina E. Calderon, Yadhira E. Garcia, Jinglong Wang, Eli M. Soyfer, Oliver S. Eng, Jennifer B. Valerin, Sora Park Tanjasiri, Fabiola Quintero-Rivera, Marcus M. Seldin, Selma Masri, Richard L. Frock, Angela G. Fleischman, Nicholas R. Pannunzio

Publikováno v: Nature Communications, Vol 15, Iss 1, Pp 1-15 (2024)

Abstract Activation-induced cytidine deaminase (AID) is a B cell-specific mutator required for antibody diversification. However, it is also implicated in the etiology of several B cell malignancies. Evaluating the AID-induced mutation load in patien

Externí odkaz: https://doaj.org/article/7199da5c9dc04e879f3964f64ebafee3

The Quality characteristics of haylage from forage grasses of tropical pastures: losses, gas production, nutritional value, microbial population and organic acids

Autor: Ricardo Loiola Edvan, Romilda Rodrigues do Nascimento, Daniel Biagiotti, Luan Felipe Reis Camboim, Lucas de Souza Barros, Tairon Pannunzio Dias e Silva, Marcos Jacome de Araújo, Leilson Rocha Bezerra

Publikováno v: Semina: Ciências Agrárias, Vol 45, Iss 6 (2024)

Tropical pastures have been little explored for haylage, due to the lack of information on nutritional quality. This study aimed to evaluate the fermentation quality of different genotypes of forage grasses from tropical pastures in the form of hayla

Externí odkaz: https://doaj.org/article/90a84012cb0740b194d0d19e5e406e93

Carcass and meat characteristics of Nellore young bulls fed diet using cottonseed cake as a replacer of the forage fiber source

Autor: Angelo Herbet Moreira Arcanjo, Luís Carlos Vinhas Ítavo, Camila Celeste Brandão Ferreira Ítavo, Marina Nadai de Bonin Gomes, Carlos Eduardo Domingues Nazário, Antonio Leandro Chaves Gurgel, Tairon Pannunzio Dias-Silva, Juliana Caroline Santos Santana, Manoel Gustavo Paranhos da Silva, Flávio de Aguiar Coelho, Estevão Lopes Miranda, Évelyn Silva de Melo Soares, Ana Hellen da Silva, Laura Beatriz Perez da Silva, Rafael Goes Cardoso Paro

Publikováno v: Scientific Reports, Vol 14, Iss 1, Pp 1-10 (2024)

Abstract The aim of this study was to assess the effects of substituting traditional forage fiber sources with cottonseed cake in the diet on both the quantitative and qualitative characteristics of carcass and meat in Nelore young bulls. Twenty-four

Externí odkaz: https://doaj.org/article/b590b28e956b42819cfd0325881f25f8

SARS-CoV-2 seroprevalence and mental health of school staff: a cross-sectional study of schools from four areas of Montreal, Quebec in 2021

Autor: Jesse Papenburg, Gaston De Serres, Guy Boivin, Caroline Quach, Kate Zinszer, Katia Charland, Marie-Ève Hamelin, Adrien Saucier, Laura Pierce, Julie Carbonneau, Cat Tuong Nguyen, Matteo Pannunzio, Eleanor Greenspan-Ardman, Margot Barbosa Da Torre

Publikováno v: BMJ Open, Vol 14, Iss 8 (2024)

Objectives To assess the seroprevalence of infection-acquired SARS-CoV-2 and the mental health of school/daycare staff in the months after reopening of schools in Montreal, Quebec (Canada) in the Fall of 2020 and whether these varied by school and pa

Externí odkaz: https://doaj.org/article/f7001470fbe34752896d3039c3484a8d

The Proton Spin Structure Function $g_2$ and Generalized Polarizabilities in the Strong QCD Regime

Autor: Ruth, D., Zielinski, R., Gu, C., Allada, M., Badman, T., Huang, M., Liu, J., Zhu, P., Allada, K., Zhang, J., Camsonne, A., Chen, J. P., Slifer, K., Aniol, K., Annand, J., Arrington, J., Averett, T., Baghdasaryan, H., Bellini, V., Boeglin, W., Brock, J., Carlin, C., Chen, C., Cisbani, E., Crabb, D., Daniel, A., Day, D., Duve, R., Fassi, L. El, Friedman, M., Fuchey, E., Gao, H., Gilman, R., Glamazdin, S., Gueye, P., Hafez, M., Han, Y., Hansen, O., Shabestari, M. Hashemi, Hen, O., Higinbotham, D., Horn, T., Iqbal, S., Jensen, E., Kang, H., Keith, C. D., Kelleher, A., Keller, D., Khanal, H., Korover, I., Kumbartzki, G., Li, W., Lichtenstadt, J., Lindgren, R., Long, E., Malace, S., Markowitz, P., Maxwell, J., Meekins, D. M., Meziani, Z. E., McLean, C., Michaels, R., Mihovilovic, M., Muangma, N., Camacho, C. Munoz, Musson, J., Myers, K., Oh, Y., Carmignotto, M. Pannunzio, Perdrisat, C., Phillips, S., Piasetzky, E., Pierce, J., Punjabi, V., Qiang, Y., Reimer, P. E., Roblin, Y., Ron, G., Rondon, O., Russo, G., Saenboonruang, K., Sawatzky, B., Shahinyan, A., Shneor, R., Sjoegren, J., Solvignon-Slifer, P., Sparveris, N., Sulkosky, V., Wesselmann, F., Yan, W., Yang, H., Yao, H., Ye, Z., Yurov, M., Zhang, Y., Zhao, Y. X., Zheng, X.

The strong interaction is not well understood at low energy, or for interactions with low momentum transfer $Q^2$, but one of the clearest insights we have comes from Chiral Perturbation Theory ($\chi$PT). This effective treatment gives testable pred

Externí odkaz: http://arxiv.org/abs/2204.10224