Genetic Analysis of mcr-1-Carrying Plasmids From Gram-Negative Bacteria in a Dutch Tertiary Care Hospital: Evidence for Intrapatient and Interspecies Transmission Events

Autor: Nikolaos Strepis, Anne F. Voor in ’t holt, Margreet C. Vos, Willemien H. A. Zandijk, Astrid P. Heikema, John P. Hays, Juliëtte A. Severin, Corné H. W. Klaassen

Publikováno v: Frontiers in Microbiology, Vol 12 (2021)

The role of plasmids in the complex pandemic of antimicrobial resistance is increasingly being recognized. In this respect, multiple mobile colistin resistance (mcr) gene-carrying plasmids have been described. However, the characteristics and epidemi

Externí odkaz: https://doaj.org/article/3172cafd8d0e439c9c5a6807983e8cc6

Biomolecule sulphation and novel methylations related to Guillain-Barré syndrome-associated

Autor: Astrid P, Heikema, Nikolaos, Strepis, Deborah, Horst-Kreft, Steven, Huynh, Aldert, Zomer, David J, Kelly, Kerry K, Cooper, Craig T, Parker

Publikováno v: Microbial Genomics

Campylobacter jejuni strains that produce sialylated lipooligosaccharides (LOS) can cause the immune-mediated disease Guillain-Barré syndrome (GBS). The risk of GBS after infection with C. jejuni Penner serotype HS:19 is estimated to be at least six

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::37520924f20b17f1956e3cda79c2a444
https://pubmed.ncbi.nlm.nih.gov/34723785

The Role of the Respiratory Microbiome and Viral Presence in Lower Respiratory Tract Infection Severity in the First Five Years of Life

Autor: Astrid P. Heikema, Janine Punt, John P. Hays, Gerdien A. Tramper-Stranders, Frank J Smit, Anne-Marie van Wermerskerken, Willem de Koning, Ivo Hoefnagels, Annemarie M. C. van Rossum, Rianne Oostenbrink, Charlie C. Obihara, Andrew P. Stubbs, Josephine van de Maat, Deborah Horst-Kreft, Jeroen J. A. van Kampen, GJ Driessen, Jeroen G. Noordzij

Publikováno v: Microorganisms, Vol 9, Iss 1446, p 1446 (2021)
Microorganisms, 9(7). Multidisciplinary Digital Publishing Institute (MDPI)
Microorganisms, 9(7):1446. Multidisciplinary Digital Publishing Institute (MDPI)
Microorganisms
Volume 9
Issue 7

Lower respiratory tract infections (LRTIs) in children are common and, although often mild, a major cause of mortality and hospitalization. Recently, the respiratory microbiome has been associated with both susceptibility and severity of LRTI. In thi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f59311a48c2a3bcbfd5f79015063fd70
https://www.mdpi.com/2076-2607/9/7/1446

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NanoGalaxy: Nanopore long-read sequencing data analysis in Galaxy

Autor: Willem de Koning, Björn Grüning, Andrew P. Stubbs, Stephan Flemming, Dana A M Mustafa, John P. Hays, Rolf Backofen, Milad Miladi, Marius van den Beek, Astrid P. Heikema, Saskia Hiltemann

Publikováno v: GigaScience, 9(10). Oxford University Press
GigaScience

Background Long-read sequencing can be applied to generate very long contigs and even completely assembled genomes at relatively low cost and with minimal sample preparation. As a result, long-read sequencing platforms are becoming more popular. In t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa50885bae78c9c1b3b05d26dfa6db2b
https://hdl.handle.net/1765/133555