Zobrazeno 1 - 10
of 2 981
pro vyhledávání: '"A P, Hoffer"'
Autor:
Mark F. Mabanglo, Brian Wilson, Mahmoud Noureldin, Serah W. Kimani, Ahmed Mamai, Chiara Krausser, Héctor González-Álvarez, Smriti Srivastava, Mohammed Mohammed, Laurent Hoffer, Manuel Chan, Jamie Avrumutsoae, Alice Shi Ming Li, Taraneh Hajian, Sarah Tucker, Stuart Green, Magdalena Szewczyk, Dalia Barsyte-Lovejoy, Vijayaratnam Santhakumar, Suzanne Ackloo, Peter Loppnau, Yanjun Li, Almagul Seitova, Taira Kiyota, Jue George Wang, Gilbert G. Privé, Douglas A. Kuntz, Bhashant Patel, Vaibhavi Rathod, Anand Vala, Bhimsen Rout, Ahmed Aman, Gennady Poda, David Uehling, Jailall Ramnauth, Levon Halabelian, Richard Marcellus, Rima Al-awar, Masoud Vedadi
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-17 (2024)
Abstract Proteolysis-targeting chimeras (PROTACs) have been explored for the degradation of drug targets for more than two decades. However, only a handful of E3 ligase substrate receptors have been efficiently used. Downregulation and mutation of th
Externí odkaz:
https://doaj.org/article/3472b510aaa44f048ba5f7afe215f30a
Autor:
Giladi, Niv, Gottlieb, Shahar, Shkolnik, Moran, Karnieli, Asaf, Banner, Ron, Hoffer, Elad, Levy, Kfir Yehuda, Soudry, Daniel
Publikováno v:
37th Conference on Neural Information Processing Systems (NeurIPS 2023)
Background: Distributed training is essential for large scale training of deep neural networks (DNNs). The dominant methods for large scale DNN training are synchronous (e.g. All-Reduce), but these require waiting for all workers in each step. Thus,
Externí odkaz:
http://arxiv.org/abs/2306.10598
Autor:
Man-Hau Ho, Yih-Jeng Tsai, Chia-Yen Chen, Anastasia Yang, Thierry Burnouf, Yun Wang, Yung-Hsiao Chiang, Barry J. Hoffer, Szu-Yi Chou
Publikováno v:
Journal of Biomedical Science, Vol 31, Iss 1, Pp 1-22 (2024)
Abstract Background Traumatic brain injury (TBI) causes axon tearing and synapse degradation, resulting in multiple neurological dysfunctions and exacerbation of early neurodegeneration; the repair of axonal and synaptic structures is critical for re
Externí odkaz:
https://doaj.org/article/a99233fd0b8446cc9e60cc3921f12614
Autor:
Khalifa, Marcel, Hoffer, Barak, Leitersdorf, Orian, Hanhan, Robert, Perach, Ben, Yavits, Leonid, Kvatinsky, Shahar
DNA sequence classification is a fundamental task in computational biology with vast implications for applications such as disease prevention and drug design. Therefore, fast high-quality sequence classifiers are significantly important. This paper i
Externí odkaz:
http://arxiv.org/abs/2302.08284
Autor:
Eric K. Hoffer, Mary C. Drinane, Vikrant Bhatnagar, Riya Mehta, David P. Munger, Andrea Borsic
Publikováno v:
International Journal of Hyperthermia, Vol 41, Iss 1 (2024)
AbstractObjectives To assess the safety and efficacy of radiofrequency ablation (RFA) guidance software that incorporated patient-specific physics-based simulation of each ablation volume.Materials and methods Patients referred for curative ablation
Externí odkaz:
https://doaj.org/article/d7e9453baaa54622a0820bfcda2a946b
Autor:
Patrick A. H. Ehm, Stefan Horn, Konstantin Hoffer, Malte Kriegs, Michael Horn, Susanne Giehler, Marcus Nalaskowski, Christoph Rehbach, Martin A. Horstmann, Manfred Jücker
Publikováno v:
Cell Communication and Signaling, Vol 22, Iss 1, Pp 1-23 (2024)
Abstract Inhibitory phosphatases, such as the inositol-5-phosphatase SHIP1 could potentially contribute to B-cell acute lymphoblastic leukemia (B-ALL) by raising the threshold for activation of the autoimmunity checkpoint, allowing malignant cells wi
Externí odkaz:
https://doaj.org/article/0e544bc1fd344d7d8ce0baab81ce998e
Autor:
Sergey A. Dyshlovoy, Wael Y. Mansour, Natalia A. Ramm, Jessica Hauschild, Maxim E. Zhidkov, Malte Kriegs, Alexandra Zielinski, Konstantin Hoffer, Tobias Busenbender, Ksenia A. Glumakova, Pavel V. Spirin, Vladimir S. Prassolov, Derya Tilki, Markus Graefen, Carsten Bokemeyer, Gunhild von Amsberg
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-17 (2024)
Abstract Fascaplysin is a red cytotoxic pigment with anticancer properties isolated from the marine sponge Fascaplysinopsis sp. Recently, structure–activity relationship analysis reported by our group suggested that selective cytotoxicity of fascap
Externí odkaz:
https://doaj.org/article/df82a4dc141245f18a09fe909aa98ef5
Autor:
Daniel J. Smit, Konstantin Hoffer, Bettina Bettin, Malte Kriegs, Laure Cayrefourcq, Udo Schumacher, Klaus Pantel, Catherine Alix‐Panabières, Manfred Jücker
Publikováno v:
Cancer Medicine, Vol 13, Iss 20, Pp n/a-n/a (2024)
ABSTRACT Background Research on circulating tumor cells (CTCs) offers the opportunity to better understand the initial steps of blood‐borne metastasis as main cause of cancer‐related deaths. Here, we have used the colon cancer CTC‐MCC‐41 and
Externí odkaz:
https://doaj.org/article/01c855f9ce71411bbeb5e216d4700d46
Autor:
Megan Hoffer, Keith Boniface
Publikováno v:
Journal of the American College of Emergency Physicians Open, Vol 5, Iss 5, Pp n/a-n/a (2024)
Externí odkaz:
https://doaj.org/article/50f7f60f24da4875b4bb4a47f8aa191f
Publikováno v:
Arthroscopy Techniques, Vol 13, Iss 10, Pp 103079- (2024)
The long head of the biceps brachii is a common pain generator in the shoulder that is often managed surgically with tenotomy or tenodesis. The clinical outcomes after tenotomy and tenodesis are comparable. However, tenodesis is preferred in the acti
Externí odkaz:
https://doaj.org/article/ee2ccebb21dd444da2833f55c8394117