Zobrazeno 1 - 10
of 173
pro vyhledávání: '"A N Fonteh"'
Autor:
K J Castor, S Shenoi, S P Edminster, T Tran, K S King, H Chui, J M Pogoda, A N Fonteh, M G Harrington
Publikováno v:
PLoS ONE, Vol 15, Iss 4, p e0231765 (2020)
Non-invasive biomarkers will enable widespread screening and early diagnosis of Alzheimer's disease (AD). We hypothesized that the considerable loss of brain tissue in AD will result in detection of brain lipid components in urine, and that these wil
Externí odkaz:
https://doaj.org/article/b61adc514e9b421e860379cd94a46677
Autor:
Chenchen Xia, Wangde Dai, Juan Carreno, Andrea Rogando, Xiaomeng Wu, Darren Simmons, Natalie Astraea, Nathan F. Dalleska, Alfred N. Fonteh, Anju Vasudevan, Xianghong Arakaki, Robert A. Kloner
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-11 (2024)
Abstract Sodium serves as one of the primary cations in the central nervous system, playing a crucial role in maintaining normal brain function. In this study, we investigated alterations in sodium concentrations in the brain and/or cerebrospinal flu
Externí odkaz:
https://doaj.org/article/8d8e175ec78e4df0a8880be01cb9bd82
Autor:
Abdulhakim Al-Ezzi, Rebecca J. Arechavala, Ryan Butler, Anne Nolty, Jimmy J. Kang, Shinsuke Shimojo, Daw-An Wu, Alfred N. Fonteh, Michael T. Kleinman, Robert A. Kloner, Xianghong Arakaki
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-15 (2024)
Abstract Alterations in functional connectivity (FC) have been observed in individuals with Alzheimer’s disease (AD) with elevated amyloid (A β) and tau. However, it is not yet known whether directed FC is already influenced by Aβ and tau load in
Externí odkaz:
https://doaj.org/article/56580c88c64742c49271041a060aa424
Autor:
Cheryl N. Fonteh, Marc T. Mathias, Naresh Mandava, Niranjan Manoharan, Anne M. Lynch, Roxanne Navo, Jennifer L. Patnaik, The University of Colorado Retina Research Group
Publikováno v:
BMC Ophthalmology, Vol 22, Iss 1, Pp 1-11 (2022)
Abstract Background Visual acuity (VA) loss has been associated with depression in patients with age-related macular degeneration (AMD). However, previous studies did not incorporate subgroups of AMD when correlating VA and mental health. The goal of
Externí odkaz:
https://doaj.org/article/a4098784a31b4f06847e50e5e78d043d
Autor:
Hussein N. Yassine, Wade Self, Bilal E. Kerman, Giulia Santoni, NandaKumar Navalpur Shanmugam, Laila Abdullah, Lesley R. Golden, Alfred N. Fonteh, Michael G. Harrington, Johannes Gräff, Gary E. Gibson, Raj Kalaria, Jose A. Luchsinger, Howard H. Feldman, Russell H. Swerdlow, Lance A. Johnson, Benedict C. Albensi, Berislav V. Zlokovic, Rudolph Tanzi, Stephen Cunnane, Cécilia Samieri, Nikolaos Scarmeas, Gene L. Bowman
Publikováno v:
Alzheimer's & Dementia. 19:1041-1066
Disturbances in the brain's capacity to meet its energy demand increase the risk of synaptic loss, neurodegeneration, and cognitive decline. Nutritional and metabolic interventions that target metabolic pathways combined with diagnostics to identify
Publikováno v:
Frontiers in Aging Neuroscience, Vol 12 (2020)
Research shows that gamma activity changes in Alzheimer’s disease (AD), revealing synaptic pathology and potential therapeutic applications. We aim to explore whether cognitive challenge combined with quantitative EEG (qEEG) can unmask abnormal gam
Externí odkaz:
https://doaj.org/article/afe7780ec0de46c59458904ce00edd1e
Publikováno v:
Frontiers in Physiology, Vol 11 (2020)
Lipids constitute the bulk of the dry mass of the brain and have been associated with healthy function as well as the most common pathological conditions of the brain. Demographic factors, genetics, and lifestyles are the major factors that influence
Externí odkaz:
https://doaj.org/article/7127c9c125c74917a62e2795f19e1c44
Autor:
Alfred N. Fonteh, Matthew Cipolla, Abby J. Chiang, Sarah P. Edminster, Xianghong Arakaki, Michael G. Harrington
Publikováno v:
Frontiers in Physiology, Vol 11 (2020)
Alzheimer’s disease (AD) pathology is characterized by an early and prolonged decrease in the amyloid peptide (Aβ) levels concomitant with a later increase in phospho-tau concentrations in cerebrospinal fluid (CSF). We propose that changes in lipi
Externí odkaz:
https://doaj.org/article/18165002730e41698947882191259244
Autor:
Lauren P. Klosinski, Jia Yao, Fei Yin, Alfred N. Fonteh, Michael G. Harrington, Trace A. Christensen, Eugenia Trushina, Roberta Diaz Brinton
Publikováno v:
EBioMedicine, Vol 2, Iss 12, Pp 1888-1904 (2015)
White matter degeneration is a pathological hallmark of neurodegenerative diseases including Alzheimer's. Age remains the greatest risk factor for Alzheimer's and the prevalence of age-related late onset Alzheimer's is greatest in females. We investi
Externí odkaz:
https://doaj.org/article/779ad5d7d6f24aa987ee0eb993c59c99
Autor:
Xianghong Arakaki, Elizabeth Hok Yee Choy, Rebecca Johnson Arechavala, Anne Nolty, Mitchell Spezzaferri, Caleb Sin, Shant Rising, David P Buennagel, Cathleen Molloy, Alfred N. Fonteh, Robert A Kloner, Michael T. Kleinman
Publikováno v:
Alzheimer's & Dementia. 18