Zobrazeno 1 - 10
of 174
pro vyhledávání: '"A N, Van Den Pol"'
Autor:
Teddy E. Kim, Shelby Puckett, Kailong Zhang, Denise M. Herpai, David A. Ornelles, John N. Davis, Anthony N. van den Pol, Waldemar Debinski, Douglas S. Lyles
Publikováno v:
Molecular Therapy: Oncolytics, Vol 22, Iss , Pp 232-244 (2021)
The difficulty of glioblastoma treatment makes it a good candidate for novel therapies, such as oncolytic viruses. Vesicular stomatitis virus expressing Lassa virus glycoprotein (Lassa-VSV) showed significant promise in animal models using establishe
Externí odkaz:
https://doaj.org/article/2b342b9766dc49d78a5a680f8de8cf26
Autor:
Shelby Puckett, Douglas S. Lyles, Teddy E. Kim, Anthony N. van den Pol, David A. Ornelles, John N. Davis, Denise Herpai, Waldemar Debinski, Kailong Zhang
Publikováno v:
Molecular Therapy: Oncolytics, Vol 22, Iss, Pp 232-244 (2021)
Molecular Therapy Oncolytics
Molecular Therapy Oncolytics
The difficulty of glioblastoma treatment makes it a good candidate for novel therapies, such as oncolytic viruses. Vesicular stomatitis virus expressing Lassa virus glycoprotein (Lassa-VSV) showed significant promise in animal models using establishe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11c98392e0f636d8e890d1df993fa577
http://www.sciencedirect.com/science/article/pii/S2372770521000826
http://www.sciencedirect.com/science/article/pii/S2372770521000826
Publikováno v:
Developmental Neurobiology. 81:389-399
Zika virus (ZIKV) can generate a number of neurological dysfunctions in infected humans. Here, we tested the potential of human immune cells to protect against ZIKV infection in genetically humanized MISTRG mice. FACS analysis showed robust reconstit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc8efddc7f06742e61cc4c53e95867de
https://doi.org/10.1002/dneu.22820
https://doi.org/10.1002/dneu.22820
Publikováno v:
The Journal of Physiology. 597:1605-1625
Key points Excitatory glutamate neurons are sparse in the rostral hypothalamic arcuate nucleus (ARC), the subregion that has received the most attention in the past. In striking contrast, excitatory neurons are far more common (by a factor of 10) in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::78c8dc2c3665a922a51a31f956447fa2
https://doi.org/10.1113/jp277152
https://doi.org/10.1113/jp277152
Autor:
Michael D. Robek, John N. Davis, Xue Zhang, Tingting Zhang, Andrea Marzi, Anthony N. van den Pol, Anthony M. Marchese
Publikováno v:
J Virol
Given that the Ebola virus (EBOV) infects a wide array of organs and cells yet displays a relative lack of neurotropism, we asked whether a chimeric vesicular stomatitis virus (VSV) expressing the EBOV glycoprotein (GP) might selectively target brain
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c663b833f5148818eb7a06f1ceb4464
https://doi.org/10.1128/jvi.01967-19
https://doi.org/10.1128/jvi.01967-19
Autor:
Yehezkel eBen-Ari, Melanie A Woodin, Evelyne eSernagor, Laura eCancedda, Laurent eVinay, Claudio eRivera, Pascal eLegendre, Heiko J Luhmann, Angelique eBordey, Peter eWenner, Atsuo eFukuda, Anthony N van den Pol, Jean-Luc eGaiarsa, Enrico eCherubini
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 6 (2012)
Abstract During brain development, there is a progressive reduction of intracellular chloride associated with a shift in GABA polarity: GABA depolarizes and occasionally excites immature neurons, subsequently hyperpolarizing them at later stages of d
Externí odkaz:
https://doaj.org/article/f1df6e10f453451ba2757dd7233a6ac8
Autor:
Anthony N. van den Pol, Xiaobing Zhang
Publikováno v:
Science. 356:853-859
A neuronal circuit for overeating Recurrent binge eating is a common eating disorder. Zhang and van den Pol investigated an understudied brain region known as the zona incerta and found that it projects inhibitory inputs to the paraventricular thalam
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0dcaca8f0e80ef899c6a54fbc6c19053
https://doi.org/10.1126/science.aam7100
https://doi.org/10.1126/science.aam7100
Autor:
Sorinel A. Oprisan, Anthony N. van den Pol, Siwei Luo, Priyattam J. Shiromani, Aurelio Vidal-Ortiz, Meng Liu, Daniel J. Spergel, Carlos Blanco-Centurion
Publikováno v:
The Journal of neuroscience : the official journal of the Society for Neuroscience. 39(25)
Most brain neurons are active in waking, but hypothalamic neurons that synthesize the neuropeptide melanin-concentrating hormone (MCH) are claimed to be active only during sleep, particularly rapid eye movement (REM) sleep. Here we use deep-brain ima
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be85ea376e01062761ec16f3101195c2
https://pubmed.ncbi.nlm.nih.gov/31036764
https://pubmed.ncbi.nlm.nih.gov/31036764
Hypothalamic arcuate nucleus tyrosine hydroxylase neurons play orexigenic role in energy homeostasis
Autor:
Anthony N. van den Pol, Xiaobing Zhang
Publikováno v:
Nature Neuroscience. 19:1341-1347
Energy homeostasis, food intake, and body weight are regulated by specific brain circuits. Here we introduce an unexpected neuron, the tyrosine hydroxylase (TH) neuron of the arcuate nucleus (ARC), that we show makes an orexigenic contribution. Optog
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::35b49c0a8c22455611a277ab0cc4fd09
https://doi.org/10.1038/nn.4372
https://doi.org/10.1038/nn.4372
Autor:
Jiansheng Su, Jenny Tong, Wenfei Han, Luis A. Tellez, Anthony N. van den Pol, Jingjing Niu, Tatiana L. Ferreira, Gary J. Schwartz, Xiaobing Zhang, Sara Medina, Ivan E. de Araujo
Publikováno v:
Cell Metabolism
Reductions in calorie intake contribute significantly to the positive outcome of bariatric surgeries. However, the physiological mechanisms linking the rerouting of the gastrointestinal tract to reductions in sugar cravings remain uncertain. We show
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::24f4e2b5dd987168dd27de28c1c52969
https://doi.org/10.1016/j.cmet.2015.10.009
https://doi.org/10.1016/j.cmet.2015.10.009