Zobrazeno 1 - 10
of 34
pro vyhledávání: '"A N, Takacs"'
Autor:
Constantin N. Takacs, Jenny Wachter, Yingjie Xiang, Zhongqing Ren, Xheni Karaboja, Molly Scott, Matthew R. Stoner, Irnov Irnov, Nicholas Jannetty, Patricia A. Rosa, Xindan Wang, Christine Jacobs-Wagner
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-6 (2023)
Externí odkaz:
https://doaj.org/article/4e657e2901f5412fbb3f5104d4097e3f
Autor:
Constantin N. Takacs, Jenny Wachter, Yingjie Xiang, Zhongqing Ren, Xheni Karaboja, Molly Scott, Matthew R. Stoner, Irnov Irnov, Nicholas Jannetty, Patricia A. Rosa, Xindan Wang, Christine Jacobs-Wagner
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-22 (2022)
Abstract Borrelia burgdorferi, the tick-transmitted spirochete agent of Lyme disease, has a highly segmented genome with a linear chromosome and various linear or circular plasmids. Here, by imaging several chromosomal loci and 16 distinct plasmids,
Externí odkaz:
https://doaj.org/article/66f28c58de054aff8c081f7314216b73
Autor:
Viet Loan Dao Thi, Xianfang Wu, Rachel L. Belote, Ursula Andreo, Constantin N. Takacs, Joseph P. Fernandez, Luis Andre Vale-Silva, Sarah Prallet, Charlotte C. Decker, Rebecca M. Fu, Bingqian Qu, Kunihiro Uryu, Henrik Molina, Mohsan Saeed, Eike Steinmann, Stephan Urban, Roshni R. Singaraja, William M. Schneider, Sanford M. Simon, Charles M. Rice
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-13 (2020)
To model hepatocyte function accurately in vitro, it is necessary to generate and maintain a polarized epithelium. Here, the authors describe a protocol to generate polarized human pluripotent stem cell-derived hepatocyte-like cells (HLCs) to model e
Externí odkaz:
https://doaj.org/article/d2bbfc7838fb493fa97035285b6d1783
Publikováno v:
PLoS ONE, Vol 17, Iss 11, p e0278151 (2022)
The spirochete Borrelia burgdorferi, which causes Lyme disease, has the most segmented genome among known bacteria. In addition to a linear chromosome, the B. burgdorferi genome contains over 20 linear and circular endogenous plasmids. While many of
Externí odkaz:
https://doaj.org/article/b6171b2af37a4cf993e7a13c9d7d44a0
Autor:
Constantin N. Takacs, Ursula Andreo, Viet Loan Dao Thi, Xianfang Wu, Caroline E. Gleason, Michelle S. Itano, Gabriella S. Spitz-Becker, Rachel L. Belote, Brenna R. Hedin, Margaret A. Scull, Charles M. Rice, Sanford M. Simon
Publikováno v:
Cell Reports, Vol 21, Iss 2, Pp 431-441 (2017)
Summary: Secretory cells produce diverse cargoes, yet how they regulate concomitant secretory traffic remains insufficiently explored. Rab GTPases control intracellular vesicular transport. To map secretion pathways, we generated a library of lentivi
Externí odkaz:
https://doaj.org/article/fa22d4a9059a426fa651430a48004744
Borrelia burgdorferi, a causative agent of Lyme disease, contains the most segmented bacterial genome known to date, with one linear chromosome and over twenty plasmids. How this unusually complex genome is organized, and whether and how the differen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6f8cd568979b945ffdaea9f6944d014d
https://doi.org/10.1101/2023.03.19.532819
https://doi.org/10.1101/2023.03.19.532819
The spirochete Borrelia burgdorferi, which causes Lyme disease, has the most segmented genome among known bacteria. In addition to a linear chromosome, the B. burgdorferi genome contains over 20 linear and circular endogenous plasmids. While many of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc207bf9ff3fadfe4cff91e23fc15857
https://doi.org/10.1101/2022.09.22.509095
https://doi.org/10.1101/2022.09.22.509095
Autor:
Constantin N Takacs, Jason Hocking, Matthew T Cabeen, Nhat Khai Bui, Sebastian Poggio, Waldemar Vollmer, Christine Jacobs-Wagner
Publikováno v:
PLoS ONE, Vol 8, Iss 2, p e57579 (2013)
The peptidoglycan (PG) is a macromolecular component of the bacterial cell wall that maintains the shape and integrity of the cell. The PG of Caulobacter crescentus, unlike that of many other Gram-negative bacteria, has repeatedly been shown to conta
Externí odkaz:
https://doaj.org/article/3cb932c87e084ae68b480e76736cf82f
Autor:
Constantin N, Takacs, Molly, Scott, Yunjie, Chang, Zachary A, Kloos, Irnov, Irnov, Patricia A, Rosa, Jun, Liu, Christine, Jacobs-Wagner
Publikováno v:
Applied and Environmental Microbiology
Gene function studies are facilitated by the availability of rapid and easy-to-use genetic tools. Homologous recombination-based methods traditionally used to genetically investigate gene function remain cumbersome to perform in B. burgdorferi, as th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::3681dbc30e1e27db0cb2ca62158e85e2
https://pubmed.ncbi.nlm.nih.gov/33257311
https://pubmed.ncbi.nlm.nih.gov/33257311
Autor:
Constantin N. Takacs, Jun Liu, Zachary A. Kloos, Patricia A. Rosa, Christine Jacobs-Wagner, Yunjie Chang, Molly Scott, Irnov Irnov
The spirochete Borrelia burgdorferi causes Lyme disease, an increasingly prevalent infection. While previous studies have provided important insight into B. burgdorferi biology, many aspects, including basic cellular processes, remain underexplored.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d007a974a3fb17296d5c61806e07034
https://doi.org/10.1101/2020.10.12.335471
https://doi.org/10.1101/2020.10.12.335471